Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SPCG_RS10615 Genome accession   NC_010582
Coordinates   1998396..1998698 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae CGSP14     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1993396..2003698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPCG_RS10580 (SPCG_2008) rnpA 1994076..1994447 (-) 372 WP_000739246.1 ribonuclease P protein component -
  SPCG_RS14075 (SPCG_2009) - 1994464..1994595 (-) 132 WP_000768904.1 hypothetical protein -
  SPCG_RS10585 (SPCG_2010) - 1994596..1995786 (-) 1191 WP_000167766.1 acetate kinase -
  SPCG_RS10590 (SPCG_2011) comYH 1995837..1996790 (-) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  SPCG_RS12795 - 1996851..1997445 (-) 595 Protein_1978 class I SAM-dependent methyltransferase -
  SPCG_RS10605 (SPCG_2014) comGG/cglG 1997548..1997994 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPCG_RS10610 (SPCG_2015) comGF/cglF 1997972..1998433 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPCG_RS10615 (SPCG_2016) comGE/cglE 1998396..1998698 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPCG_RS10620 (SPCG_2017) comGD/cglD 1998661..1999065 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPCG_RS10625 (SPCG_2018) comGC/cglC 1999058..1999384 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  SPCG_RS10630 (SPCG_2019) comGB/cglB 1999386..2000402 (-) 1017 WP_078134418.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPCG_RS10635 (SPCG_2020) comGA/cglA/cilD 2000350..2001291 (-) 942 WP_000249573.1 competence type IV pilus ATPase ComGA Machinery gene
  SPCG_RS10640 (SPCG_2021) - 2001367..2001732 (-) 366 WP_000286415.1 DUF1033 family protein -
  SPCG_RS10645 (SPCG_2022) - 2001883..2002941 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=30646 SPCG_RS10615 WP_000413382.1 1998396..1998698(-) (comGE/cglE) [Streptococcus pneumoniae CGSP14]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=30646 SPCG_RS10615 WP_000413382.1 1998396..1998698(-) (comGE/cglE) [Streptococcus pneumoniae CGSP14]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment