NTDB

Overview

Name	comX/comX2	Type	Regulator
Locus tag	SP70585_RS00105	Genome accession	NC_012468
Coordinates	15872..16351 (+)	Length	159 a.a.
NCBI ID	WP_000588873.1	Uniprot ID	-
Organism	Streptococcus pneumoniae 70585
Function	activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 10872..21351

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP70585_RS00090 (SP70585_0012)	hpt	11812..12354 (+)	543	WP_000892184.1	hypoxanthine phosphoribosyltransferase	-
SP70585_RS00095 (SP70585_0013)	ftsH	12370..14328 (+)	1959	WP_000744551.1	ATP-dependent zinc metalloprotease FtsH	-
SP70585_RS00100 (SP70585_0014)	-	14392..15648 (-)	1257	WP_000436399.1	ISL3 family transposase	-
SP70585_RS00105 (SP70585_0015)	comX/comX2	15872..16351 (+)	480	WP_000588873.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

Download Length: 159 a.a. Molecular weight: 19845.50 Da Isoelectric Point: 7.3795

                                >NTDB_id=29968 SP70585_RS00105 WP_000588873.1 15872..16351(+) (comX/comX2) [Streptococcus pneumoniae 70585]

MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRK

YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide

Download Length: 480 bp

                                >NTDB_id=29968 SP70585_RS00105 WP_000588873.1 15872..16351(+) (comX/comX2) [Streptococcus pneumoniae 70585]

ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTTTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT

GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC

GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAAA

TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA

TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA

ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains

No domain identified.

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comX/comX2	Streptococcus pneumoniae Rx1	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae Rx1	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae D39	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae D39	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae R6	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae R6	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae TIGR4	98.742	100	0.987
comX/comX1	Streptococcus pneumoniae TIGR4	98.742	100	0.987
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	91.824	100	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	91.824	100	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	89.937	100	0.899
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	88.608	99.371	0.881
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	49.359	98.113	0.484
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	49.359	98.113	0.484
comX/sigX	Streptococcus suis D9	46.358	94.969	0.44
comX/sigX	Streptococcus suis isolate S10	46.358	94.969	0.44
comX/sigX	Streptococcus suis P1/7	46.358	94.969	0.44
comX/sigX	Streptococcus mutans UA159	45.333	94.34	0.428
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40	94.34	0.377

Detailed information NTG0029968