Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DEH83_RS05575 Genome accession   NZ_CP029207
Coordinates   1089277..1090218 (+) Length   313 a.a.
NCBI ID   WP_219123646.1    Uniprot ID   -
Organism   Streptococcus constellatus strain TCV107     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1084277..1095218
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DEH83_RS05545 (DEH83_05530) - 1085671..1085877 (+) 207 WP_006268044.1 hypothetical protein -
  DEH83_RS05550 (DEH83_05535) - 1085880..1086164 (+) 285 WP_006269982.1 2'-5' RNA ligase family protein -
  DEH83_RS05555 (DEH83_05540) - 1086303..1086833 (+) 531 WP_003027011.1 aromatic acid exporter family protein -
  DEH83_RS05560 (DEH83_05545) - 1086910..1087269 (+) 360 WP_003070793.1 MerR family transcriptional regulator -
  DEH83_RS05565 (DEH83_05550) glnA 1087308..1088654 (+) 1347 WP_006269977.1 type I glutamate--ammonia ligase -
  DEH83_RS05570 (DEH83_05555) - 1088842..1089207 (+) 366 WP_255776366.1 DUF1033 family protein -
  DEH83_RS05575 (DEH83_05560) comYA 1089277..1090218 (+) 942 WP_219123646.1 competence type IV pilus ATPase ComGA Machinery gene
  DEH83_RS05580 (DEH83_05565) comYB 1090160..1091182 (+) 1023 WP_255777234.1 competence type IV pilus assembly protein ComGB Machinery gene
  DEH83_RS05585 (DEH83_05570) comYC 1091179..1091496 (+) 318 WP_006269985.1 competence type IV pilus major pilin ComGC Machinery gene
  DEH83_RS05590 (DEH83_05575) comYD 1091456..1091884 (+) 429 WP_255776367.1 competence type IV pilus minor pilin ComGD Machinery gene
  DEH83_RS05595 (DEH83_05580) comGE/cglE 1091856..1092149 (+) 294 WP_006269989.1 competence type IV pilus minor pilin ComGE Machinery gene
  DEH83_RS05600 (DEH83_05585) comGF/cglF 1092133..1092570 (+) 438 WP_049476068.1 competence type IV pilus minor pilin ComGF Machinery gene
  DEH83_RS05605 (DEH83_05590) comGG 1092551..1092877 (+) 327 WP_003070783.1 competence type IV pilus minor pilin ComGG -
  DEH83_RS05610 (DEH83_05595) comYH 1092962..1093915 (+) 954 WP_255776368.1 class I SAM-dependent methyltransferase Machinery gene
  DEH83_RS05615 (DEH83_05600) - 1093962..1095161 (+) 1200 WP_255776369.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35974.13 Da        Isoelectric Point: 6.1148

>NTDB_id=291186 DEH83_RS05575 WP_219123646.1 1089277..1090218(+) (comYA) [Streptococcus constellatus strain TCV107]
MVQNIAQAIICQAKEERAQDIYFVPKENVYELYMRIGDERRFIRNYEFEELAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YSDKKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFADQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSERYQEHEPSDWNKQIDQLYAAGHITFEQAETEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=291186 DEH83_RS05575 WP_219123646.1 1089277..1090218(+) (comYA) [Streptococcus constellatus strain TCV107]
ATGGTTCAAAACATTGCACAGGCTATTATTTGTCAGGCTAAGGAAGAACGAGCACAGGACATTTATTTTGTTCCGAAGGA
AAATGTTTACGAGTTGTATATGCGAATTGGAGATGAACGCCGTTTTATACGCAATTATGAATTTGAAGAGCTAGCTGCTG
TAATCAGTCATTTCAAGTTTACTGCTGGGATGAATGTGGGAGAAAAACGTCGCAGTCAGCTGGGCTCTTGCGATTATCAA
TATAGTGACAAGAAAACGTCGCTACGGTTATCAACAGTGGGGGATTATCGCGGATATGAAAGTCTAGTGATTCGTCTATT
GCATGATGAAGAAGCAGAGCTGAAGTTTTGGTTTGCTCAAATTCCGGAGTTGAAAGAACGTTTCAAACAGCGAGGGCTTT
ACCTTTTTTCAGGACCGGTAGGAAGTGGTAAAACTACTCTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCGATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATAAAACTTTCTCTTCGGCATCGACCGGATTTATTGATTATCGGAGAGATTCGTGATGCGGAGACAG
CACGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCAGAGCTGAAAATTGTTTTGCAAGGAATTTGCTACCAACGGTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAGGTATCAAGAGCATGAGCCAAGTGACTGGAATAAGCAGATTGATCAGC
TTTATGCAGCAGGACATATCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

83.226

99.042

0.824
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

76.038

100

0.76
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.719

100

0.757
  comYA Streptococcus mutans UA159

64.63

99.361

0.642
  comYA Streptococcus mutans UA140

64.63

99.361

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.361

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

42.657

91.374

0.39

Multiple sequence alignment