Detailed information    

insolico Bioinformatically predicted

Overview


Name   pilA2   Type   Machinery gene
Locus tag   CAB17_RS03705 Genome accession   NZ_CP025491
Coordinates   845735..846166 (-) Length   143 a.a.
NCBI ID   WP_058513121.1    Uniprot ID   A0A2H5FLJ7
Organism   Legionella sainthelensi strain LA01-117     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 840735..851166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAB17_RS03680 (CAB17_10305) - 840820..842775 (+) 1956 WP_101900040.1 ATP-dependent DNA helicase -
  CAB17_RS03685 (CAB17_10310) tsaB 842756..843406 (+) 651 WP_101900041.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB -
  CAB17_RS03690 (CAB17_10315) - 843416..843595 (+) 180 WP_027270259.1 Trm112 family protein -
  CAB17_RS03695 (CAB17_10320) - 843760..845160 (-) 1401 WP_027270258.1 APC family permease -
  CAB17_RS03700 (CAB17_10325) - 845325..845648 (-) 324 WP_101900042.1 BolA family protein -
  CAB17_RS03705 (CAB17_10330) pilA2 845735..846166 (-) 432 WP_058513121.1 pilin Machinery gene
  CAB17_RS03710 (CAB17_10335) - 846454..847698 (-) 1245 WP_101900043.1 6-phosphofructokinase -
  CAB17_RS03715 (CAB17_10340) letS 847739..850474 (-) 2736 WP_101900044.1 two-component system sensor histidine kinase LetS Regulator

Sequence


Protein


Download         Length: 143 a.a.        Molecular weight: 14706.91 Da        Isoelectric Point: 7.7799

>NTDB_id=261983 CAB17_RS03705 WP_058513121.1 845735..846166(-) (pilA2) [Legionella sainthelensi strain LA01-117]
MKQKGFTLIELMIVVAIIGILAAIAIPAYQDYVVRARVTEGLSLASAAKTTVSENASSGAAKLSQGWVAPTATANVKSVA
VDDNTGKITITYDAPAKSIVITLTPQSGGAALVAGTPPTDAITWTCAVDQAANDRYVPSNCRI

Nucleotide


Download         Length: 432 bp        

>NTDB_id=261983 CAB17_RS03705 WP_058513121.1 845735..846166(-) (pilA2) [Legionella sainthelensi strain LA01-117]
ATGAAGCAAAAGGGTTTTACTTTAATTGAATTGATGATAGTAGTGGCAATCATTGGAATTCTCGCCGCAATCGCTATTCC
TGCATATCAAGACTATGTCGTTAGAGCTCGTGTTACGGAAGGATTAAGCCTTGCCTCTGCAGCAAAAACGACAGTTTCTG
AGAACGCATCAAGTGGCGCTGCGAAATTAAGTCAGGGCTGGGTTGCCCCTACAGCAACTGCTAATGTGAAAAGCGTTGCT
GTTGATGATAATACGGGAAAAATCACTATCACTTATGATGCGCCGGCAAAAAGCATTGTTATTACTTTAACCCCACAATC
TGGTGGTGCAGCTCTTGTTGCTGGTACCCCGCCAACAGATGCTATTACCTGGACTTGTGCGGTTGATCAGGCTGCAAACG
ACCGATATGTTCCGTCCAATTGCCGTATTTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A2H5FLJ7

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA2 Legionella pneumophila strain ERS1305867

53.378

100

0.552

  pilA2 Legionella pneumophila str. Paris

53.378

100

0.552

  pilA Ralstonia pseudosolanacearum GMI1000

49.682

100

0.545

  comP Acinetobacter baylyi ADP1

47.742

100

0.517

  pilA/pilA1 Eikenella corrodens VA1

42.138

100

0.469

  pilA Pseudomonas aeruginosa PAK

39.355

100

0.427

  pilA Acinetobacter baumannii strain A118

41.216

100

0.427

  pilE Neisseria gonorrhoeae MS11

35.976

100

0.413

  pilE Neisseria gonorrhoeae strain FA1090

35.065

100

0.378

  pilA/pilAII Pseudomonas stutzeri DSM 10701

37.324

99.301

0.371

  pilA/pilAI Pseudomonas stutzeri DSM 10701

36.364

100

0.364


Multiple sequence alignment