Detailed information NTG0261984

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: CAB17_RS03715
• Genome accession: NZ_CP025491
• Coordinates: 847739..850474 (-)
• Length: 911 a.a.
• NCBI ID: WP_101900044.1
• Uniprot ID: -
• Organism: Legionella sainthelensi strain LA01-117
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 842739..855474

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CAB17_RS03685 (CAB17_10310)	tsaB	842756..843406 (+)	651	WP_101900041.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	-
CAB17_RS03690 (CAB17_10315)	-	843416..843595 (+)	180	WP_027270259.1	Trm112 family protein	-
CAB17_RS03695 (CAB17_10320)	-	843760..845160 (-)	1401	WP_027270258.1	APC family permease	-
CAB17_RS03700 (CAB17_10325)	-	845325..845648 (-)	324	WP_101900042.1	BolA family protein	-
CAB17_RS03705 (CAB17_10330)	pilA2	845735..846166 (-)	432	WP_058513121.1	pilin	Machinery gene
CAB17_RS03710 (CAB17_10335)	-	846454..847698 (-)	1245	WP_101900043.1	6-phosphofructokinase	-
CAB17_RS03715 (CAB17_10340)	letS	847739..850474 (-)	2736	WP_101900044.1	two-component system sensor histidine kinase LetS	Regulator
CAB17_RS03720 (CAB17_10345)	gltX	850603..852018 (+)	1416	WP_101900045.1	glutamate--tRNA ligase	-
CAB17_RS03725 (CAB17_10350)	-	852015..853289 (+)	1275	WP_101900046.1	serine hydrolase domain-containing protein	-
CAB17_RS03730 (CAB17_10355)	-	853430..854407 (+)	978	WP_101900047.1	hypothetical protein	-
CAB17_RS03735 (CAB17_10360)	gstA	854466..855068 (+)	603	WP_101900048.1	glutathione transferase GstA	-

Sequence

Protein

• Length: 911 a.a.
• Molecular weight: 102656.30 Da
• Isoelectric Point: 8.1133

>NTDB_id=261984 CAB17_RS03715 WP_101900044.1 847739..850474(-) (letS) [Legionella sainthelensi strain LA01-117]
MLKSIGIKYQLRITTLIPVFLVALLLAIFYNGLFGNDLKQHMSRLGEAYIRQLLPAAQYAMLRGDDRTLQGLINASTINP
EVKALAFYSSDGQLLAYRGGKHSLSKPFTAPKFTGDYIKSKQINPFTINFIAPVTIPKFNLYSNSSFKNILSPMASRADD
ILGWLSIDIDTRSMIIKRYQMLIVTIFITLFGLLVGLTIHYFLSKQIYLPISRLRRSMKQILRNEFETEIKTTSSGELGI
IEQGCSHLQKKHLETIRDLNHHIEVATADLQQSLELLEEKNIELSLEKKKIEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLALAAPNAHKKGIDLIPITE
LNVPKIVLGDPFRVKQFISNLVTNAVKFTDHGYVLIRTKVEQETDRDYTLCITITDTGLGISPEDQNKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMKGRITFASELNKGSVFTAYIKVEKLVAYEVEKNQVHPFAHFKMLCFDDNPMQLEALCNG
LGYWGIKCIAVPSLNQLANKLKNNKDCNIAFLNINKGYEQQITKLIAEHNYFPYVLTSKWLINDYTALGAQGFLYKPISI
QKLQDIIESLTNQENIEKSVNHELEGLREQLRFLHPDLLIAEDNPVNKMLLDSLLGTRANIVAVDNGEMAVSVCNEKKYS
LILLDLHMPKINGLEAARLIRQKSEFNRHTPIVLISANGRDVNDIDLKKSGVNFCLQKPIDEKQLLIQILRIADKAKHSA
IDWQLCVQKASGNQSLAEEFLARFVEELIKNREELIQLMHEKNVKQLGEAAHKLHGACCFSGVPTLQKKVVQVEKLAAHA
ASIAELATPFAELIQSIDAVISEYENQKIKT

Nucleotide

• Length: 2736 bp

>NTDB_id=261984 CAB17_RS03715 WP_101900044.1 847739..850474(-) (letS) [Legionella sainthelensi strain LA01-117]
ATCTTGAAAAGCATTGGTATTAAGTATCAACTAAGAATTACTACTTTAATCCCTGTTTTTCTGGTCGCCCTACTCCTTGC
CATTTTTTATAATGGATTGTTTGGTAATGACTTAAAACAACACATGTCTCGCCTAGGTGAAGCATATATTCGACAATTAC
TACCAGCCGCCCAGTATGCTATGCTGCGTGGGGACGATCGAACCTTACAAGGTCTTATCAATGCATCAACAATTAATCCT
GAAGTCAAAGCACTCGCTTTTTACAGTAGCGATGGCCAACTCCTTGCTTATCGTGGGGGCAAACATTCACTAAGCAAACC
ATTTACTGCACCTAAATTCACTGGGGATTACATTAAAAGTAAACAAATTAATCCCTTTACTATCAACTTTATCGCCCCTG
TCACAATTCCAAAATTTAATTTGTATTCCAACTCTTCTTTTAAAAATATTTTAAGCCCGATGGCATCTCGAGCTGATGAT
ATTCTTGGTTGGTTGTCTATTGATATCGATACTCGCTCAATGATAATCAAACGTTATCAGATGCTTATTGTCACTATTTT
CATTACTTTATTCGGGTTATTAGTAGGATTAACCATTCACTACTTTCTCTCGAAACAAATTTATTTACCTATTTCTCGTT
TGCGAAGGAGCATGAAGCAAATTTTACGAAACGAGTTTGAAACAGAGATAAAAACAACCAGCTCTGGAGAATTAGGAATA
ATTGAACAAGGTTGCTCGCATTTGCAAAAAAAACACCTTGAAACGATACGCGATCTAAACCACCACATTGAAGTAGCAAC
GGCTGATTTACAACAAAGTTTAGAGCTTTTAGAGGAAAAAAATATTGAACTTTCCCTTGAAAAGAAAAAAATAGAAGAAA
AAAGCCGGCAAAAGTCTGAATTTATCGCCAATATGAGTCATGAAATTCGTACTCCGATGAATGGAGTTATTGGTTTTACT
AATGTTTTACTTGAAAGTAAACTTGATCCTTTGCAATTAGATTATGTAAAAACAATTAAGTCATCAGCACAAGACTTATT
GGGGATCATCAATGACATTCTCGATTTCTCAAAAATTGATGCGGGAAAACTTCATCTCGATTGTATTCCATTAAATATTC
GCCACTGTATTGATGAAGTACTCGCTCTCGCAGCACCTAATGCCCATAAAAAAGGAATCGACTTAATTCCTATAACCGAA
CTAAACGTACCTAAGATTGTTTTAGGAGATCCCTTTAGAGTAAAACAGTTTATTAGCAACCTGGTTACTAATGCAGTTAA
ATTTACTGATCATGGATATGTATTAATCCGTACTAAAGTAGAGCAGGAAACAGATAGAGATTACACTTTATGCATTACAA
TTACGGATACAGGCTTAGGTATTTCTCCTGAAGATCAGAACAAGTTGTTTACCGCCTTTAATCAGGCAGATACCAGTATT
ACCCGTCGTTATGGCGGCTCAGGACTTGGTTTGGTAATCTGTAAAAAACTCTGTGAAGAAATGAAAGGCCGTATTACTTT
TGCCAGTGAACTCAACAAAGGTTCTGTTTTTACTGCTTATATCAAGGTTGAAAAATTAGTTGCCTATGAAGTTGAGAAAA
ATCAAGTTCATCCTTTTGCTCATTTTAAAATGCTTTGTTTTGACGATAACCCCATGCAGCTGGAGGCCTTGTGTAATGGA
TTAGGGTATTGGGGAATCAAATGTATCGCTGTACCTTCACTAAATCAACTCGCGAATAAGCTGAAAAATAATAAAGATTG
CAACATCGCTTTTCTTAATATCAATAAAGGTTACGAACAACAAATTACTAAGCTAATAGCCGAGCATAATTATTTTCCTT
ATGTGTTGACCTCTAAATGGCTTATTAATGATTATACAGCACTTGGAGCCCAAGGATTTTTATATAAACCCATTAGTATC
CAAAAACTCCAAGATATTATTGAATCATTAACAAACCAAGAAAATATTGAAAAGTCAGTTAATCATGAATTAGAAGGTTT
AAGAGAACAATTACGTTTCCTACATCCAGATCTTCTTATAGCTGAAGATAATCCAGTGAATAAAATGCTTCTTGACTCTT
TATTAGGTACTCGTGCCAATATTGTAGCGGTTGATAATGGAGAAATGGCTGTATCGGTGTGTAATGAAAAGAAATACAGT
CTTATCTTACTTGACCTGCATATGCCTAAAATAAATGGCTTAGAAGCCGCTCGACTTATCCGTCAAAAATCAGAATTTAA
TCGTCATACACCCATAGTATTAATTAGTGCAAATGGTAGAGATGTAAATGATATTGATTTAAAAAAATCAGGGGTAAATT
TTTGTTTGCAAAAACCCATAGATGAAAAACAATTATTGATCCAAATTTTACGTATTGCAGATAAAGCAAAGCACTCTGCA
ATAGATTGGCAATTGTGTGTTCAAAAAGCCTCTGGAAATCAATCACTAGCCGAGGAGTTCCTTGCTCGATTTGTAGAAGA
ATTGATTAAAAACCGTGAAGAACTCATCCAATTAATGCATGAAAAAAATGTGAAACAATTGGGGGAAGCAGCACATAAAC
TTCATGGAGCATGTTGTTTTAGTGGTGTCCCCACGTTACAAAAAAAGGTAGTTCAAGTAGAAAAACTTGCTGCTCATGCT
GCTTCAATCGCAGAATTAGCTACTCCTTTTGCAGAATTAATTCAAAGCATCGACGCAGTAATTAGTGAATACGAAAATCA
AAAAATAAAAACGTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (679-787)

• Hpt domain (Hpt) (819-900)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Single cache domain 4 (sCache_4) (36-180)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	78.39	99.561	0.78