Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   CWI26_RS00810 Genome accession   NZ_CP025043
Coordinates   133507..134457 (+) Length   316 a.a.
NCBI ID   WP_044760311.1    Uniprot ID   -
Organism   Streptococcus suis strain AH681     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 128507..139457
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS00795 (CWI26_00795) - 130432..131688 (-) 1257 WP_100881034.1 ISL3 family transposase -
  CWI26_RS00800 (CWI26_00800) - 131967..132326 (+) 360 WP_044776736.1 DUF1033 family protein -
  CWI26_RS00805 (CWI26_00805) - 132471..133421 (-) 951 WP_100881035.1 S66 family peptidase -
  CWI26_RS00810 (CWI26_00810) comYA 133507..134457 (+) 951 WP_044760311.1 competence type IV pilus ATPase ComGA Machinery gene
  CWI26_RS00815 (CWI26_00815) comYB 134369..135406 (+) 1038 WP_233486262.1 competence type IV pilus assembly protein ComGB Machinery gene
  CWI26_RS00820 (CWI26_00820) comYC 135408..135689 (+) 282 WP_044760307.1 competence type IV pilus major pilin ComGC Machinery gene
  CWI26_RS00825 (CWI26_00825) comGD 135670..136077 (+) 408 WP_100881037.1 competence type IV pilus minor pilin ComGD -
  CWI26_RS00830 (CWI26_00830) comYE 136049..136342 (+) 294 WP_100881038.1 competence type IV pilus minor pilin ComGE Machinery gene
  CWI26_RS00835 (CWI26_00835) comGF/cglF 136329..136763 (+) 435 WP_100881039.1 competence type IV pilus minor pilin ComGF Machinery gene
  CWI26_RS00840 (CWI26_00840) comGG 136741..137268 (+) 528 WP_029180264.1 competence type IV pilus minor pilin ComGG -
  CWI26_RS00845 (CWI26_00845) comYH 137325..138278 (+) 954 WP_100881040.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35410.29 Da        Isoelectric Point: 5.4744

>NTDB_id=257589 CWI26_RS00810 WP_044760311.1 133507..134457(+) (comYA) [Streptococcus suis strain AH681]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGAPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=257589 CWI26_RS00810 WP_044760311.1 133507..134457(+) (comYA) [Streptococcus suis strain AH681]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTATCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGTCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACGCTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTTGAAATCAAGCAGGAGGATATGCTACAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATTAAACTGTCTCTCCGTCATCGGCCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGTCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
GCCCGTATGTTGGAATTGGGGGTCAGTCCTGAAGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGCTTAATCGG
AGGAGGAGGTGTAGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCGCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

69.032

98.101

0.677
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

98.418

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.312

100

0.535
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361

Multiple sequence alignment