Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   CWI26_RS00830 Genome accession   NZ_CP025043
Coordinates   136049..136342 (+) Length   97 a.a.
NCBI ID   WP_100881038.1    Uniprot ID   A0A2I5KLD0
Organism   Streptococcus suis strain AH681     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 131049..141342
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS00800 (CWI26_00800) - 131967..132326 (+) 360 WP_044776736.1 DUF1033 family protein -
  CWI26_RS00805 (CWI26_00805) - 132471..133421 (-) 951 WP_100881035.1 S66 family peptidase -
  CWI26_RS00810 (CWI26_00810) comYA 133507..134457 (+) 951 WP_044760311.1 competence type IV pilus ATPase ComGA Machinery gene
  CWI26_RS00815 (CWI26_00815) comYB 134369..135406 (+) 1038 WP_233486262.1 competence type IV pilus assembly protein ComGB Machinery gene
  CWI26_RS00820 (CWI26_00820) comYC 135408..135689 (+) 282 WP_044760307.1 competence type IV pilus major pilin ComGC Machinery gene
  CWI26_RS00825 (CWI26_00825) comGD 135670..136077 (+) 408 WP_100881037.1 competence type IV pilus minor pilin ComGD -
  CWI26_RS00830 (CWI26_00830) comYE 136049..136342 (+) 294 WP_100881038.1 competence type IV pilus minor pilin ComGE Machinery gene
  CWI26_RS00835 (CWI26_00835) comGF/cglF 136329..136763 (+) 435 WP_100881039.1 competence type IV pilus minor pilin ComGF Machinery gene
  CWI26_RS00840 (CWI26_00840) comGG 136741..137268 (+) 528 WP_029180264.1 competence type IV pilus minor pilin ComGG -
  CWI26_RS00845 (CWI26_00845) comYH 137325..138278 (+) 954 WP_100881040.1 class I SAM-dependent methyltransferase Machinery gene
  CWI26_RS00850 (CWI26_00850) - 138328..139515 (+) 1188 WP_100881041.1 acetate kinase -
  CWI26_RS00860 (CWI26_00860) - 139829..140380 (+) 552 WP_100881043.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10876.81 Da        Isoelectric Point: 9.0152

>NTDB_id=257592 CWI26_RS00830 WP_100881038.1 136049..136342(+) (comYE) [Streptococcus suis strain AH681]
MVVIRKQKNKAYILLESLVALATLVTICSLILSAVDAGRRRQAWELEQQEVLNLAQMAVQTKQDYLALNGVTVQVQRTAD
EIIVFHEGKEVLSVVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=257592 CWI26_RS00830 WP_100881038.1 136049..136342(+) (comYE) [Streptococcus suis strain AH681]
GTGGTCGTTATAAGAAAACAGAAGAATAAGGCTTATATTTTGCTAGAAAGTCTGGTTGCCCTTGCGACCTTAGTGACTAT
TTGCAGCTTGATTTTATCAGCTGTGGATGCAGGTCGTAGGCGACAGGCTTGGGAATTGGAACAACAGGAGGTTCTCAATC
TAGCACAGATGGCTGTCCAGACCAAACAAGATTATTTAGCCTTAAACGGTGTTACAGTTCAGGTTCAACGAACTGCGGAT
GAGATTATTGTTTTCCACGAGGGAAAGGAGGTTCTATCAGTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2I5KLD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

55.67

100

0.557
  comYE Streptococcus mutans UA159

55.67

100

0.557
  comGE/cglE Streptococcus pneumoniae Rx1

39.56

93.814

0.371
  comGE/cglE Streptococcus pneumoniae D39

39.56

93.814

0.371
  comGE/cglE Streptococcus pneumoniae R6

39.56

93.814

0.371
  comGE/cglE Streptococcus pneumoniae TIGR4

39.56

93.814

0.371
  comGE/cglE Streptococcus mitis SK321

38.462

93.814

0.361
  comGE/cglE Streptococcus mitis NCTC 12261

38.462

93.814

0.361

Multiple sequence alignment