Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   CWI26_RS00815 Genome accession   NZ_CP025043
Coordinates   134369..135406 (+) Length   345 a.a.
NCBI ID   WP_233486262.1    Uniprot ID   -
Organism   Streptococcus suis strain AH681     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 129369..140406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWI26_RS00795 (CWI26_00795) - 130432..131688 (-) 1257 WP_100881034.1 ISL3 family transposase -
  CWI26_RS00800 (CWI26_00800) - 131967..132326 (+) 360 WP_044776736.1 DUF1033 family protein -
  CWI26_RS00805 (CWI26_00805) - 132471..133421 (-) 951 WP_100881035.1 S66 family peptidase -
  CWI26_RS00810 (CWI26_00810) comYA 133507..134457 (+) 951 WP_044760311.1 competence type IV pilus ATPase ComGA Machinery gene
  CWI26_RS00815 (CWI26_00815) comYB 134369..135406 (+) 1038 WP_233486262.1 competence type IV pilus assembly protein ComGB Machinery gene
  CWI26_RS00820 (CWI26_00820) comYC 135408..135689 (+) 282 WP_044760307.1 competence type IV pilus major pilin ComGC Machinery gene
  CWI26_RS00825 (CWI26_00825) comGD 135670..136077 (+) 408 WP_100881037.1 competence type IV pilus minor pilin ComGD -
  CWI26_RS00830 (CWI26_00830) comYE 136049..136342 (+) 294 WP_100881038.1 competence type IV pilus minor pilin ComGE Machinery gene
  CWI26_RS00835 (CWI26_00835) comGF/cglF 136329..136763 (+) 435 WP_100881039.1 competence type IV pilus minor pilin ComGF Machinery gene
  CWI26_RS00840 (CWI26_00840) comGG 136741..137268 (+) 528 WP_029180264.1 competence type IV pilus minor pilin ComGG -
  CWI26_RS00845 (CWI26_00845) comYH 137325..138278 (+) 954 WP_100881040.1 class I SAM-dependent methyltransferase Machinery gene
  CWI26_RS00850 (CWI26_00850) - 138328..139515 (+) 1188 WP_100881041.1 acetate kinase -
  CWI26_RS00860 (CWI26_00860) - 139829..140380 (+) 552 WP_100881043.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 39015.02 Da        Isoelectric Point: 9.6164

>NTDB_id=257590 CWI26_RS00815 WP_233486262.1 134369..135406(+) (comYB) [Streptococcus suis strain AH681]
MRKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVAVLAGMVWFRKTNKIKVFSRLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQS
QQSQLFREIGQDLEQSLSNGQSFHEHIKNYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=257590 CWI26_RS00815 WP_233486262.1 134369..135406(+) (comYB) [Streptococcus suis strain AH681]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCGCG
CCAGCGTAAGGTCATTGAACTGTTTAACAATCTCTTTGCCAGTGGCTTTCATCTGGGAGAGATTGTTGATTTCCTCAAAC
GTAGTCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGCTGTTAGCAGGCAAACCCTTTTCAAGTTTGCTG
GCGGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAGGTTCATGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCAACCTATCCGATAATCTTGC
TTGGTTTTCTGCTCTTGATTATGCTAGGCTTGAAAAACTATCTTTTGCCCCAGTTGGAGGAAGGTAATGCAGCGACTATG
CTGATAAATCATCTGCCGACTATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGAAAAACCAACAAAATTAAGGTATTTTCCCGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGTTTGGACCTGCCGCAGATTGTGGGCTTGATGCAATCG
CAGCAATCGCAACTCTTTCGGGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGCTTTCACGAACACAT
TAAGAATTACGCTTTTTTTAAGCGAGAGTTGAGTTTGATTGTCGAGTACGGTCAGGTCAAGTCCAAGTTGGGGAGCGAGT
TGACGGTTTATGCGGCTGAATGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTTATCTACGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.45

99.13

0.629
  comGB/cglB Streptococcus mitis NCTC 12261

60.299

97.101

0.586
  comGB/cglB Streptococcus mitis SK321

60

97.101

0.583
  comYB Streptococcus mutans UA140

58.944

98.841

0.583
  comYB Streptococcus mutans UA159

58.944

98.841

0.583
  comGB/cglB Streptococcus pneumoniae Rx1

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae D39

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae R6

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae TIGR4

59.701

97.101

0.58
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493

Multiple sequence alignment