Detailed information NTG0025436

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SAOUHSC_01221
• Genome accession: NC_007795
• Coordinates: 1171904..1172644 (+)
• Length: 246 a.a.
• NCBI ID: YP_499757.1
• Uniprot ID: Q2FZ33
• Organism: Staphylococcus aureus subsp. aureus NCTC 8325
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1166904..1177644

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAOUHSC_01218	-	1168074..1168982 (+)	909	YP_499754.1	succinyl-CoA synthetase subunit alpha	-
SAOUHSC_01219	-	1169209..1170327 (+)	1119	YP_499755.1	cell wall hydrolase	-
SAOUHSC_01220	-	1170355..1171599 (+)	1245	YP_499756.1	hypothetical protein	-
SAOUHSC_01221	dprA	1171904..1172644 (+)	741	YP_499757.1	hypothetical protein	Machinery gene
SAOUHSC_01222	-	1172818..1174893 (+)	2076	YP_499758.1	DNA topoisomerase I	-
SAOUHSC_01223	-	1175049..1176356 (+)	1308	YP_499759.1	tRNA (uracil-5-)-methyltransferase Gid	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28166.57 Da
• Isoelectric Point: 9.3425

>NTDB_id=25436 SAOUHSC_01221 YP_499757.1 1171904..1172644(+) (dprA) [Staphylococcus aureus subsp. aureus NCTC 8325]
MNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDS
TSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQIALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPP
HTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDI
FEDYYI

Nucleotide

• Length: 741 bp

>NTDB_id=25436 SAOUHSC_01221 YP_499757.1 1171904..1172644(+) (dprA) [Staphylococcus aureus subsp. aureus NCTC 8325]
GTGAATAGGGAAGAAAATGTTCATTTATTACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGA
ACTGCAGAAATTAAAAGTAAGTTACATTACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTC
CATTACTTCTTTTCTATAAAGGGAACATCAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCT
ACAAGTTATACCCAACAGTCTTTAGAATTTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGC
TCAAGGAGCTGATGCAATGGCACATCAAATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATC
AAACACATTATCCCAAAAGTACATTAGCATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCTGAATATCCACCA
CATACACCAATCGCTAAATATAGATTTCCTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGA
GGCTAAGGAACAAAGTGGCAGTCACATCACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGAT
CTATGTTTAATCCTATGACAAAAGGTAATTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATA
TTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (28-235)

3D structure

• AlphaFold DB: Q2FZ33

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Staphylococcus aureus MW2	99.593	100	0.996
dprA	Staphylococcus aureus N315	99.187	100	0.992
dprA	Legionella pneumophila strain ERS1305867	42.06	94.715	0.398
dprA	Lactococcus lactis subsp. cremoris KW2	41.126	93.902	0.386
dprA	Latilactobacillus sakei subsp. sakei 23K	44.393	86.992	0.386
dprA/cilB/dalA	Streptococcus pneumoniae R6	40.611	93.089	0.378
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	40.611	93.089	0.378
dprA/cilB/dalA	Streptococcus pneumoniae D39	40.611	93.089	0.378
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	40.611	93.089	0.378
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	40.611	93.089	0.378
dprA	Streptococcus mutans UA159	41.15	91.87	0.378
dprA/cilB/dalA	Streptococcus mitis SK321	40.175	93.089	0.374
dprA	Acinetobacter baylyi ADP1	37.097	100	0.374
dprA	Glaesserella parasuis strain SC1401	38.983	95.935	0.374
dprA	Haemophilus influenzae Rd KW20	42.453	86.179	0.366
dprA	Bacillus subtilis subsp. subtilis str. 168	42.654	85.772	0.366