Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   CO204_RS01180 Genome accession   NZ_CP023477
Coordinates   228756..229697 (+) Length   313 a.a.
NCBI ID   WP_002264247.1    Uniprot ID   -
Organism   Streptococcus mutans strain LAR01     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 223756..234697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO204_RS01170 (CO204_01170) rpoC 224486..228115 (+) 3630 WP_002263433.1 DNA-directed RNA polymerase subunit beta' -
  CO204_RS01175 (CO204_01175) - 228243..228626 (+) 384 WP_002269807.1 DUF1033 family protein -
  CO204_RS01180 (CO204_01180) comYA 228756..229697 (+) 942 WP_002264247.1 competence type IV pilus ATPase ComGA Machinery gene
  CO204_RS01185 (CO204_01185) comYB 229633..230664 (+) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  CO204_RS01190 (CO204_01190) comYC 230664..230978 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  CO204_RS01195 (CO204_01195) comYD 230965..231369 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  CO204_RS01200 (CO204_01200) comYE 231341..231634 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  CO204_RS01205 (CO204_01205) comYF 231621..232055 (+) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  CO204_RS01210 (CO204_01210) comYG 232033..232422 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  CO204_RS01215 (CO204_01215) comYH 232477..233430 (+) 954 WP_002269808.1 class I SAM-dependent methyltransferase Machinery gene
  CO204_RS01220 (CO204_01220) - 233489..234688 (+) 1200 WP_002263443.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35667.03 Da        Isoelectric Point: 8.5765

>NTDB_id=247394 CO204_RS01180 WP_002264247.1 228756..229697(+) (comYA) [Streptococcus mutans strain LAR01]
MVQKLGRKIIAEAVQNKAQDIYIIPKKESYELYMRIGNERRFIDVYDHHFMANLISHFKFVAGMNVGEKRRSQLGSCDYS
YDEGKVISLRLSSVGDYRGYESLVIRLLFSGRHDLKFWFNSMDLILNEIKGRGLYLFSGPVGSGKTSLMYQLVKLRFGTK
QVITIEDPVEIKQDNMLQLQLNESIDMTYDNLIKLSLRHRPDILIIGEIRDKETARAVIRASLTGAMVFSTIHAKSIPGV
YARMLELGTSSEELQNALRGIVYQRLIGGGGIIDFAKGDYQNHSAKKWNKQIYDLFTAGYITEGEAQAEEIED

Nucleotide


Download         Length: 942 bp        

>NTDB_id=247394 CO204_RS01180 WP_002264247.1 228756..229697(+) (comYA) [Streptococcus mutans strain LAR01]
ATGGTTCAAAAATTAGGTAGAAAAATCATTGCCGAAGCTGTTCAAAATAAAGCACAAGATATCTATATTATTCCTAAAAA
AGAATCTTATGAGCTTTATATGAGAATAGGGAATGAAAGGAGGTTCATTGATGTTTATGACCATCATTTCATGGCTAATC
TTATTAGTCACTTTAAATTTGTTGCAGGAATGAATGTTGGTGAGAAAAGACGAAGTCAGCTGGGCTCTTGTGATTATTCT
TATGATGAAGGGAAAGTTATTTCATTAAGGTTATCAAGTGTAGGAGATTATCGTGGTTATGAAAGTTTGGTTATTCGCTT
ACTTTTTTCTGGACGTCACGATTTAAAATTCTGGTTTAACAGTATGGATTTGATTTTAAATGAAATCAAGGGGCGAGGGC
TTTATCTTTTTTCAGGTCCAGTTGGAAGTGGCAAAACAAGTTTGATGTATCAATTGGTAAAACTAAGATTTGGGACCAAA
CAGGTAATTACCATTGAAGATCCTGTGGAAATTAAGCAAGATAATATGTTACAACTGCAGCTTAATGAAAGCATTGATAT
GACTTATGATAATTTAATTAAATTATCTCTGAGGCATCGTCCGGATATTTTAATTATTGGAGAAATTCGAGATAAAGAAA
CCGCCAGAGCTGTTATTAGAGCAAGTCTTACAGGGGCAATGGTATTCTCAACTATCCATGCTAAAAGCATTCCAGGTGTT
TATGCTAGGATGTTAGAATTGGGTACTAGTTCAGAAGAATTACAAAATGCTTTGCGTGGTATTGTTTATCAACGTTTAAT
AGGGGGAGGAGGGATTATTGACTTTGCCAAAGGGGATTATCAAAACCACTCAGCAAAAAAGTGGAACAAACAAATTTATG
ACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

99.681

100

0.997
  comYA Streptococcus mutans UA140

99.361

100

0.994
  comYA Streptococcus gordonii str. Challis substr. CH1

67.093

100

0.671
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.026

99.681

0.658
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.916

99.361

0.655
  comGA Lactococcus lactis subsp. cremoris KW2

52.412

99.361

0.521

Multiple sequence alignment