Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   CO204_RS01200 Genome accession   NZ_CP023477
Coordinates   231341..231634 (+) Length   97 a.a.
NCBI ID   WP_002263439.1    Uniprot ID   -
Organism   Streptococcus mutans strain LAR01     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 226341..236634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO204_RS01175 (CO204_01175) - 228243..228626 (+) 384 WP_002269807.1 DUF1033 family protein -
  CO204_RS01180 (CO204_01180) comYA 228756..229697 (+) 942 WP_002264247.1 competence type IV pilus ATPase ComGA Machinery gene
  CO204_RS01185 (CO204_01185) comYB 229633..230664 (+) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  CO204_RS01190 (CO204_01190) comYC 230664..230978 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  CO204_RS01195 (CO204_01195) comYD 230965..231369 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  CO204_RS01200 (CO204_01200) comYE 231341..231634 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  CO204_RS01205 (CO204_01205) comYF 231621..232055 (+) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  CO204_RS01210 (CO204_01210) comYG 232033..232422 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  CO204_RS01215 (CO204_01215) comYH 232477..233430 (+) 954 WP_002269808.1 class I SAM-dependent methyltransferase Machinery gene
  CO204_RS01220 (CO204_01220) - 233489..234688 (+) 1200 WP_002263443.1 acetate kinase -
  CO204_RS01225 (CO204_01225) tnpA 234901..235364 (+) 464 Protein_206 IS200/IS605 family transposase -
  CO204_RS01235 (CO204_01235) - 235992..236237 (+) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11001.91 Da        Isoelectric Point: 9.4908

>NTDB_id=247398 CO204_RS01200 WP_002263439.1 231341..231634(+) (comYE) [Streptococcus mutans strain LAR01]
MVSIKKQKVKAYILLESLVALGLFVTITTLILTQLSHYQERTAKNLQKQEILNLAIMALQTQQDHLSFNGVSVTVVKNQG
ETIVYHDHEEVINLVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=247398 CO204_RS01200 WP_002263439.1 231341..231634(+) (comYE) [Streptococcus mutans strain LAR01]
GTGGTCAGTATAAAAAAACAGAAAGTTAAAGCTTATATTCTTCTAGAAAGTTTAGTTGCTTTGGGGCTTTTCGTAACCAT
CACAACTTTAATTCTTACTCAGTTGAGTCATTATCAGGAAAGAACAGCTAAAAATTTACAAAAACAAGAAATATTGAATT
TAGCAATAATGGCTCTTCAAACTCAGCAAGATCATTTAAGCTTCAACGGCGTCAGTGTTACGGTTGTTAAAAATCAAGGG
GAAACTATAGTTTATCATGATCATGAGGAGGTTATCAATCTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

100

100

1
  comYE Streptococcus mutans UA159

100

100

1
  comGE/cglE Streptococcus pneumoniae Rx1

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae D39

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae R6

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae TIGR4

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis NCTC 12261

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis SK321

44.444

92.784

0.412

Multiple sequence alignment