Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   CO204_RS01185 Genome accession   NZ_CP023477
Coordinates   229633..230664 (+) Length   343 a.a.
NCBI ID   WP_255262721.1    Uniprot ID   -
Organism   Streptococcus mutans strain LAR01     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 224633..235664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO204_RS01175 (CO204_01175) - 228243..228626 (+) 384 WP_002269807.1 DUF1033 family protein -
  CO204_RS01180 (CO204_01180) comYA 228756..229697 (+) 942 WP_002264247.1 competence type IV pilus ATPase ComGA Machinery gene
  CO204_RS01185 (CO204_01185) comYB 229633..230664 (+) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  CO204_RS01190 (CO204_01190) comYC 230664..230978 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  CO204_RS01195 (CO204_01195) comYD 230965..231369 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  CO204_RS01200 (CO204_01200) comYE 231341..231634 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  CO204_RS01205 (CO204_01205) comYF 231621..232055 (+) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  CO204_RS01210 (CO204_01210) comYG 232033..232422 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  CO204_RS01215 (CO204_01215) comYH 232477..233430 (+) 954 WP_002269808.1 class I SAM-dependent methyltransferase Machinery gene
  CO204_RS01220 (CO204_01220) - 233489..234688 (+) 1200 WP_002263443.1 acetate kinase -
  CO204_RS01225 (CO204_01225) tnpA 234901..235364 (+) 464 Protein_206 IS200/IS605 family transposase -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39844.46 Da        Isoelectric Point: 9.5151

>NTDB_id=247395 CO204_RS01185 WP_255262721.1 229633..230664(+) (comYB) [Streptococcus mutans strain LAR01]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQLERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=247395 CO204_RS01185 WP_255262721.1 229633..230664(+) (comYB) [Streptococcus mutans strain LAR01]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGCATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

100

100

1
  comYB Streptococcus mutans UA140

99.417

100

0.994
  comYB Streptococcus gordonii str. Challis substr. CH1

60.058

100

0.601
  comGB/cglB Streptococcus mitis NCTC 12261

58.407

98.834

0.577
  comGB/cglB Streptococcus mitis SK321

56.548

97.959

0.554
  comGB/cglB Streptococcus pneumoniae Rx1

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae D39

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae R6

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae TIGR4

55.952

97.959

0.548
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

98.251

0.507

Multiple sequence alignment