Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYD   Type   Machinery gene
Locus tag   CO204_RS01195 Genome accession   NZ_CP023477
Coordinates   230965..231369 (+) Length   134 a.a.
NCBI ID   WP_002263438.1    Uniprot ID   -
Organism   Streptococcus mutans strain LAR01     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 225965..236369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO204_RS01175 (CO204_01175) - 228243..228626 (+) 384 WP_002269807.1 DUF1033 family protein -
  CO204_RS01180 (CO204_01180) comYA 228756..229697 (+) 942 WP_002264247.1 competence type IV pilus ATPase ComGA Machinery gene
  CO204_RS01185 (CO204_01185) comYB 229633..230664 (+) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  CO204_RS01190 (CO204_01190) comYC 230664..230978 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  CO204_RS01195 (CO204_01195) comYD 230965..231369 (+) 405 WP_002263438.1 competence type IV pilus minor pilin ComGD Machinery gene
  CO204_RS01200 (CO204_01200) comYE 231341..231634 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  CO204_RS01205 (CO204_01205) comYF 231621..232055 (+) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  CO204_RS01210 (CO204_01210) comYG 232033..232422 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  CO204_RS01215 (CO204_01215) comYH 232477..233430 (+) 954 WP_002269808.1 class I SAM-dependent methyltransferase Machinery gene
  CO204_RS01220 (CO204_01220) - 233489..234688 (+) 1200 WP_002263443.1 acetate kinase -
  CO204_RS01225 (CO204_01225) tnpA 234901..235364 (+) 464 Protein_206 IS200/IS605 family transposase -
  CO204_RS01235 (CO204_01235) - 235992..236237 (+) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -

Sequence


Protein


Download         Length: 134 a.a.        Molecular weight: 15444.77 Da        Isoelectric Point: 9.5619

>NTDB_id=247397 CO204_RS01195 WP_002263438.1 230965..231369(+) (comYD) [Streptococcus mutans strain LAR01]
MSRIKAFTLIESLVTLAITSFLILSFSGSITQTFAKVEERLFFLSFEHLYRDTQKLSVYQRQDMTLILKSEYISNGVEVL
KIPKDVKLERNKTLHFDQAGGNSSLEKLVFQTSDEKRVTYQLYIGSGQYKKTES

Nucleotide


Download         Length: 405 bp        

>NTDB_id=247397 CO204_RS01195 WP_002263438.1 230965..231369(+) (comYD) [Streptococcus mutans strain LAR01]
ATGTCGCGAATTAAAGCTTTTACGCTTATAGAAAGTTTAGTGACTTTGGCAATTACTAGTTTTTTGATTTTAAGCTTTTC
AGGTAGTATAACTCAAACGTTTGCCAAAGTAGAAGAGCGTCTCTTTTTTCTTTCTTTTGAACATCTTTACCGTGACACGC
AAAAACTTAGTGTTTATCAAAGACAAGATATGACTTTAATATTAAAAAGCGAATATATATCAAATGGTGTTGAAGTACTT
AAAATCCCTAAGGATGTCAAACTAGAGAGGAATAAAACTTTGCACTTTGATCAGGCAGGAGGAAATTCTTCTTTAGAAAA
ACTTGTTTTTCAAACATCTGATGAAAAAAGAGTTACTTATCAATTATATATAGGAAGTGGTCAGTATAAAAAAACAGAAA
GTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYD Streptococcus mutans UA140

100

100

1

  comYD Streptococcus mutans UA159

100

100

1

  comYD Streptococcus gordonii str. Challis substr. CH1

50.388

96.269

0.485

  comGD/cglD Streptococcus mitis NCTC 12261

49.612

96.269

0.478

  comGD/cglD Streptococcus pneumoniae Rx1

49.219

95.522

0.47

  comGD/cglD Streptococcus pneumoniae D39

49.219

95.522

0.47

  comGD/cglD Streptococcus pneumoniae R6

49.219

95.522

0.47

  comGD/cglD Streptococcus pneumoniae TIGR4

48.438

95.522

0.463

  comGD/cglD Streptococcus mitis SK321

48.438

95.522

0.463

  comGD Lactococcus lactis subsp. cremoris KW2

39.394

98.507

0.388


Multiple sequence alignment