Detailed information NTG0241029

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: Sp14A_RS00750
• Genome accession: NZ_CP022601
• Coordinates: 124222..124515 (+)
• Length: 97 a.a.
• NCBI ID: WP_115129539.1
• Uniprot ID: A0A345VHA6
• Organism: Streptococcus pluranimalium strain 14A0014
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 119222..129515

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Sp14A_RS00735 (Sp14A_01490)	-	121873..122253 (+)	381	WP_205407082.1	DUF1033 family protein	-
Sp14A_RS00740 (Sp14A_01500)	comYA	122316..123269 (+)	954	WP_115129537.1	competence type IV pilus ATPase ComGA	Machinery gene
Sp14A_RS00745 (Sp14A_01510)	comYB	123193..124221 (+)	1029	WP_115129538.1	competence type IV pilus assembly protein ComGB	Machinery gene
Sp14A_RS00750 (Sp14A_01520)	comYC	124222..124515 (+)	294	WP_115129539.1	competence type IV pilus major pilin ComGC	Machinery gene
Sp14A_RS00755 (Sp14A_01530)	comGD	124496..124912 (+)	417	WP_104967107.1	competence type IV pilus minor pilin ComGD	-
Sp14A_RS00760	comGE	124884..125183 (+)	300	WP_115129540.1	competence type IV pilus minor pilin ComGE	-
Sp14A_RS00765 (Sp14A_01540)	comYF	125161..125598 (+)	438	WP_115129541.1	competence type IV pilus minor pilin ComGF	Machinery gene
Sp14A_RS00770 (Sp14A_01550)	comGG	125582..125977 (+)	396	WP_205407083.1	competence type IV pilus minor pilin ComGG	-
Sp14A_RS00775 (Sp14A_01560)	comYH	126020..126973 (+)	954	WP_115129542.1	class I SAM-dependent methyltransferase	Machinery gene
Sp14A_RS00780 (Sp14A_01570)	-	127034..128224 (+)	1191	WP_115129543.1	acetate kinase	-
Sp14A_RS00785 (Sp14A_01580)	-	128609..128806 (+)	198	WP_115129544.1	helix-turn-helix transcriptional regulator	-
Sp14A_RS00790 (Sp14A_01590)	-	128819..129271 (+)	453	WP_115129545.1	hypothetical protein	-

Sequence

Protein

• Length: 97 a.a.
• Molecular weight: 11062.14 Da
• Isoelectric Point: 9.8115

>NTDB_id=241029 Sp14A_RS00750 WP_115129539.1 124222..124515(+) (comYC) [Streptococcus pluranimalium strain 14A0014]
MTYYWKQVKRKSVKGFTLLEMLFVLLIISVLMLLFVPNLSKQKAAVDEKGKAAVVKVVESQMELYEMKEDAKPSIQQLVD
GGYITQKQADTYAEAKK

Nucleotide

• Length: 294 bp

>NTDB_id=241029 Sp14A_RS00750 WP_115129539.1 124222..124515(+) (comYC) [Streptococcus pluranimalium strain 14A0014]
GTGACATATTATTGGAAACAAGTTAAACGAAAAAGTGTAAAAGGGTTCACTCTTCTAGAAATGCTCTTCGTGCTTCTTAT
CATCAGTGTGCTTATGCTTTTGTTTGTGCCTAATTTGAGCAAGCAAAAGGCAGCTGTTGATGAAAAAGGAAAGGCAGCAG
TGGTGAAGGTTGTCGAGAGTCAGATGGAGTTGTATGAAATGAAAGAAGATGCCAAACCATCTATTCAACAATTAGTGGAT
GGTGGTTATATTACGCAAAAGCAAGCTGATACTTATGCAGAAGCTAAGAAGTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (10-34)

3D structure

• AlphaFold DB: A0A345VHA6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	67.059	87.629	0.588
comYC	Streptococcus gordonii str. Challis substr. CH1	63.636	90.722	0.577
comGC/cglC	Streptococcus pneumoniae D39	62.069	89.691	0.557
comGC/cglC	Streptococcus pneumoniae R6	62.069	89.691	0.557
comGC/cglC	Streptococcus pneumoniae TIGR4	62.069	89.691	0.557
comGC/cglC	Streptococcus mitis SK321	62.069	89.691	0.557
comGC/cglC	Streptococcus mitis NCTC 12261	62.069	89.691	0.557
comGC/cglC	Streptococcus pneumoniae Rx1	62.069	89.691	0.557
comYC	Streptococcus mutans UA140	58.427	91.753	0.536
comYC	Streptococcus mutans UA159	58.427	91.753	0.536
comGC	Lactococcus lactis subsp. cremoris KW2	54.348	94.845	0.515
comGC	Staphylococcus aureus MW2	46.835	81.443	0.381
comGC	Staphylococcus aureus N315	46.835	81.443	0.381