Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   Sp14A_RS00740 Genome accession   NZ_CP022601
Coordinates   122316..123269 (+) Length   317 a.a.
NCBI ID   WP_115129537.1    Uniprot ID   A0A345VHA4
Organism   Streptococcus pluranimalium strain 14A0014     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 117316..128269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS00730 (Sp14A_01480) rpoC 117863..121495 (+) 3633 WP_104967104.1 DNA-directed RNA polymerase subunit beta' -
  Sp14A_RS00735 (Sp14A_01490) - 121873..122253 (+) 381 WP_205407082.1 DUF1033 family protein -
  Sp14A_RS00740 (Sp14A_01500) comYA 122316..123269 (+) 954 WP_115129537.1 competence type IV pilus ATPase ComGA Machinery gene
  Sp14A_RS00745 (Sp14A_01510) comYB 123193..124221 (+) 1029 WP_115129538.1 competence type IV pilus assembly protein ComGB Machinery gene
  Sp14A_RS00750 (Sp14A_01520) comYC 124222..124515 (+) 294 WP_115129539.1 competence type IV pilus major pilin ComGC Machinery gene
  Sp14A_RS00755 (Sp14A_01530) comGD 124496..124912 (+) 417 WP_104967107.1 competence type IV pilus minor pilin ComGD -
  Sp14A_RS00760 comGE 124884..125183 (+) 300 WP_115129540.1 competence type IV pilus minor pilin ComGE -
  Sp14A_RS00765 (Sp14A_01540) comYF 125161..125598 (+) 438 WP_115129541.1 competence type IV pilus minor pilin ComGF Machinery gene
  Sp14A_RS00770 (Sp14A_01550) comGG 125582..125977 (+) 396 WP_205407083.1 competence type IV pilus minor pilin ComGG -
  Sp14A_RS00775 (Sp14A_01560) comYH 126020..126973 (+) 954 WP_115129542.1 class I SAM-dependent methyltransferase Machinery gene
  Sp14A_RS00780 (Sp14A_01570) - 127034..128224 (+) 1191 WP_115129543.1 acetate kinase -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35811.83 Da        Isoelectric Point: 5.6770

>NTDB_id=241027 Sp14A_RS00740 WP_115129537.1 122316..123269(+) (comYA) [Streptococcus pluranimalium strain 14A0014]
MVQDLAKELIVQAVEYEAQDIYIIPRKDDYDVFMRINDERRFIETHGFDRMASLISHFKFVAGMTVGEKRRSQLGSCDYD
IGSAKLVSLRLSTVGDYRGHESLVIRLLHDGRQDLRYWFNGIRNIMAEFSSRGLYLFSGPTGSGKTTLMYQLLKEKCKDK
QIISIEDPVEIKDDSILQLQLNEDIGMTYDSLIKLSLRHRPDVLVIGEIRDTQTAQAAIRASLTGATVFATIHAKSIPGV
YYRMIELGVSKDDLKNSLAGVCYQRLIGGGGLIDVAKDKFQDHSPSQWNQYLVELFEAGYITEEQVKAESISYSEAG

Nucleotide


Download         Length: 954 bp        

>NTDB_id=241027 Sp14A_RS00740 WP_115129537.1 122316..123269(+) (comYA) [Streptococcus pluranimalium strain 14A0014]
ATGGTTCAAGATTTAGCAAAGGAACTGATTGTTCAGGCAGTCGAATATGAAGCTCAAGATATTTATATCATTCCTAGAAA
GGATGATTACGATGTTTTTATGCGTATTAATGATGAGAGGAGATTTATTGAAACTCATGGCTTTGATCGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGAATGACTGTCGGGGAAAAGCGCCGAAGTCAACTAGGATCTTGTGATTATGAT
ATTGGTAGTGCTAAGCTAGTTTCTTTACGCCTCTCAACTGTTGGAGATTACCGAGGGCATGAGAGTTTGGTGATTCGCCT
GCTGCATGATGGGCGTCAGGACTTACGCTATTGGTTCAATGGTATACGTAATATCATGGCAGAATTTAGTTCCAGAGGTC
TATATCTTTTTTCGGGACCGACTGGGAGCGGCAAAACGACTCTCATGTATCAATTGTTAAAGGAGAAATGTAAAGATAAA
CAGATTATTTCTATTGAAGATCCGGTTGAAATCAAGGATGATAGCATTTTACAATTACAGCTTAATGAAGATATTGGTAT
GACTTACGATAGTCTGATTAAGTTGTCGTTGAGACATCGTCCAGATGTATTGGTTATTGGTGAAATTCGGGATACGCAAA
CAGCGCAAGCGGCTATTCGAGCTAGTTTGACTGGTGCTACAGTCTTTGCAACCATTCATGCTAAGAGTATTCCAGGGGTT
TATTACCGCATGATAGAATTGGGTGTTTCTAAAGATGATCTAAAAAATAGTCTAGCGGGAGTTTGTTATCAACGTTTGAT
AGGAGGAGGTGGATTGATAGATGTGGCAAAAGATAAGTTCCAGGATCACTCACCAAGCCAGTGGAACCAATACTTGGTTG
AGCTTTTTGAAGCAGGATATATCACTGAGGAGCAGGTTAAAGCCGAGAGTATTAGCTATTCAGAAGCAGGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A345VHA4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

66.238

98.107

0.65
  comYA Streptococcus mutans UA159

66.238

98.107

0.65
  comYA Streptococcus gordonii str. Challis substr. CH1

63.924

99.685

0.637
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.102

99.054

0.615
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

97.792

0.615
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.783

99.054

0.612
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.783

99.054

0.612
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.783

99.054

0.612
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.783

99.054

0.612
  comGA Lactococcus lactis subsp. cremoris KW2

51.42

100

0.514

Multiple sequence alignment