Detailed information NTG0235407

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: SE071780_RS00705
• Genome accession: NZ_CP021972
• Coordinates: 121204..121527 (+)
• Length: 107 a.a.
• NCBI ID: WP_012514782.1
• Uniprot ID: B4U056
• Organism: Streptococcus equi subsp. equi strain ATCC 39506
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 116204..126527

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SE071780_RS00685 (SE071780_00137)	-	116464..118467 (+)	2004	WP_012678808.1	DUF1430 domain-containing protein	-
SE071780_RS00690 (SE071780_00138)	-	118469..119116 (+)	648	WP_012678809.1	ATP-binding cassette domain-containing protein	-
SE071780_RS00695 (SE071780_00139)	comGA/cglA	119298..120236 (+)	939	WP_012678810.1	competence type IV pilus ATPase ComGA	Machinery gene
SE071780_RS00700 (SE071780_00140)	comYB	120169..121203 (+)	1035	WP_012678811.1	competence type IV pilus assembly protein ComGB	Machinery gene
SE071780_RS00705 (SE071780_00141)	comGC/cglC	121204..121527 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
SE071780_RS00710 (SE071780_00142)	comGD	121505..121930 (+)	426	WP_012678812.1	competence type IV pilus minor pilin ComGD	-
SE071780_RS00715	comGE	121887..122177 (+)	291	WP_012678813.1	competence type IV pilus minor pilin ComGE	-
SE071780_RS00720 (SE071780_00143)	comYF	122164..122598 (+)	435	WP_012678814.1	competence type IV pilus minor pilin ComGF	Machinery gene
SE071780_RS00725 (SE071780_00144)	comGG	122576..122938 (+)	363	WP_012678815.1	competence type IV pilus minor pilin ComGG	-
SE071780_RS00730	-	123004..124346 (+)	1343	Protein_108	IS3 family transposase	-
SE071780_RS00735 (SE071780_00148)	comYH	124431..125384 (+)	954	WP_012678816.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 12149.19 Da
• Isoelectric Point: 8.4057

>NTDB_id=235407 SE071780_RS00705 WP_012514782.1 121204..121527(+) (comGC/cglC) [Streptococcus equi subsp. equi strain ATCC 39506]
MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE
DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide

• Length: 324 bp

>NTDB_id=235407 SE071780_RS00705 WP_012514782.1 121204..121527(+) (comGC/cglC) [Streptococcus equi subsp. equi strain ATCC 39506]
ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTGTTAAT
CATTAGTGTTTTGATGCTGTTATTTGTTCCAAATTTAAGTAAACAAAAGGATAAGGTGACAGACACAGGCAATGCTGCGG
TGGTAAAGCTGGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG
GATGGAAGTATCAGTGACAAGCAGCAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: B4U056

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis SK321	59.813	100	0.598
comGC/cglC	Streptococcus pneumoniae Rx1	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae D39	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae R6	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae TIGR4	57.944	100	0.579
comYC	Streptococcus gordonii str. Challis substr. CH1	62.245	91.589	0.57
comGC/cglC	Streptococcus mitis NCTC 12261	61.616	92.523	0.57
comYC	Streptococcus mutans UA140	58.763	90.654	0.533
comYC	Streptococcus mutans UA159	58.763	90.654	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	56.842	88.785	0.505
comYC	Streptococcus suis isolate S10	60	74.766	0.449
comGC	Staphylococcus aureus MW2	50	72.897	0.364
comGC	Staphylococcus aureus N315	50	72.897	0.364