Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   SE071780_RS00720 Genome accession   NZ_CP021972
Coordinates   122164..122598 (+) Length   144 a.a.
NCBI ID   WP_012678814.1    Uniprot ID   -
Organism   Streptococcus equi subsp. equi strain ATCC 39506     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 123004..128261 122164..122598 flank 406


Gene organization within MGE regions


Location: 122164..128261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SE071780_RS00720 (SE071780_00143) comYF 122164..122598 (+) 435 WP_012678814.1 competence type IV pilus minor pilin ComGF Machinery gene
  SE071780_RS00725 (SE071780_00144) comGG 122576..122938 (+) 363 WP_012678815.1 competence type IV pilus minor pilin ComGG -
  SE071780_RS00730 - 123004..124346 (+) 1343 Protein_108 IS3 family transposase -
  SE071780_RS00735 (SE071780_00148) comYH 124431..125384 (+) 954 WP_012678816.1 class I SAM-dependent methyltransferase Machinery gene
  SE071780_RS00740 (SE071780_00149) - 125444..126643 (+) 1200 WP_012678817.1 acetate kinase -
  SE071780_RS00745 - 126910..128261 (+) 1352 WP_173476793.1 IS3 family transposase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16152.66 Da        Isoelectric Point: 10.3349

>NTDB_id=235408 SE071780_RS00720 WP_012678814.1 122164..122598(+) (comYF) [Streptococcus equi subsp. equi strain ATCC 39506]
MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAANDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDK
KALSFGQVKGHDFRKAASNGQGYQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG

Nucleotide


Download         Length: 435 bp        

>NTDB_id=235408 SE071780_RS00720 WP_012678814.1 122164..122598(+) (comYF) [Streptococcus equi subsp. equi strain ATCC 39506]
TTGAAAGACAGTAGGCTAAAGGCTTTCACCTTGATAGAGTGCCTTATTGCCTTGCTTGTCATCTCAGGCTCTTTATTAGT
TTATCAGGCCTTAACCAAGAGCCTTATGGCAAATGAGAGGTATCTAGCAGCAAATGATCAGAACAACTGGCTTTTGTTTT
CCCAGCAATTGCGAGCAGAGCTTTCAGGTACTACCCTACAGGGTGTCCGCAATAATAGGCTATATGTTGAAAAGGACAAG
AAGGCTTTGTCCTTTGGACAGGTCAAGGGCCATGATTTTAGAAAAGCAGCTAGCAATGGTCAAGGCTATCAGCCCATGCT
GTTTGGCTTGTCAAGTAGCCAAATAACAGCAGTAGGTCAGCAGGTGACCATCAAGCTGAAATGGCAAAGCGGCTTAGAAA
GGACCTTTATTTATGCATTTCAAGAGAAGGGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(38-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

52.448

99.306

0.521
  comYF Streptococcus mutans UA159

51.748

99.306

0.514
  comGF/cglF Streptococcus mitis SK321

48.905

95.139

0.465
  comGF Lactococcus lactis subsp. cremoris KW2

47.482

96.528

0.458
  comGF/cglF Streptococcus mitis NCTC 12261

48.175

95.139

0.458
  comGF/cglF Streptococcus pneumoniae Rx1

46.715

95.139

0.444
  comGF/cglF Streptococcus pneumoniae D39

46.715

95.139

0.444
  comGF/cglF Streptococcus pneumoniae R6

46.715

95.139

0.444
  comGF/cglF Streptococcus pneumoniae TIGR4

46.715

95.139

0.444

Multiple sequence alignment