Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SE071780_RS00700 Genome accession   NZ_CP021972
Coordinates   120169..121203 (+) Length   344 a.a.
NCBI ID   WP_012678811.1    Uniprot ID   -
Organism   Streptococcus equi subsp. equi strain ATCC 39506     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115169..126203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SE071780_RS00680 (SE071780_00136) - 115562..115927 (+) 366 WP_012514777.1 DUF1033 family protein -
  SE071780_RS00685 (SE071780_00137) - 116464..118467 (+) 2004 WP_012678808.1 DUF1430 domain-containing protein -
  SE071780_RS00690 (SE071780_00138) - 118469..119116 (+) 648 WP_012678809.1 ATP-binding cassette domain-containing protein -
  SE071780_RS00695 (SE071780_00139) comGA/cglA 119298..120236 (+) 939 WP_012678810.1 competence type IV pilus ATPase ComGA Machinery gene
  SE071780_RS00700 (SE071780_00140) comYB 120169..121203 (+) 1035 WP_012678811.1 competence type IV pilus assembly protein ComGB Machinery gene
  SE071780_RS00705 (SE071780_00141) comGC/cglC 121204..121527 (+) 324 WP_012514782.1 competence type IV pilus major pilin ComGC Machinery gene
  SE071780_RS00710 (SE071780_00142) comGD 121505..121930 (+) 426 WP_012678812.1 competence type IV pilus minor pilin ComGD -
  SE071780_RS00715 comGE 121887..122177 (+) 291 WP_012678813.1 competence type IV pilus minor pilin ComGE -
  SE071780_RS00720 (SE071780_00143) comYF 122164..122598 (+) 435 WP_012678814.1 competence type IV pilus minor pilin ComGF Machinery gene
  SE071780_RS00725 (SE071780_00144) comGG 122576..122938 (+) 363 WP_012678815.1 competence type IV pilus minor pilin ComGG -
  SE071780_RS00730 - 123004..124346 (+) 1343 Protein_108 IS3 family transposase -
  SE071780_RS00735 (SE071780_00148) comYH 124431..125384 (+) 954 WP_012678816.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39431.69 Da        Isoelectric Point: 9.4359

>NTDB_id=235406 SE071780_RS00700 WP_012678811.1 120169..121203(+) (comYB) [Streptococcus equi subsp. equi strain ATCC 39506]
MISFLRRDISIPGRQGLKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYVTSMEASLLKGNGLADMLAAL
GYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKRKTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLL
HLPHYFLGFCLLVLLLIGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEMMSNEKS
QLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELDIYSQESWETFFSQLNRATQWIQPIIFLV
VAVVIVMIYAAILLPIYQQMGDVF

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=235406 SE071780_RS00700 WP_012678811.1 120169..121203(+) (comYB) [Streptococcus equi subsp. equi strain ATCC 39506]
TTGATCAGCTTCTTGCGGAGGGACATCTCAATACCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAAGCAGCAGGAAAA
GCTTATCCAATTGCTCTATAACCTATTGTCTAACGGCTTTAATTTGACAGAGGTCATTGCTTTTTTGAGAAAAAGCCAGC
TGCTACTGCCAGTCTATGTTACAAGTATGGAAGCAAGCCTATTAAAGGGCAACGGCCTTGCTGACATGCTAGCAGCCTTA
GGTTACTCTGATGCTGTTATGACACAAATTAATCTGGCAGATAAGCATGGCAATATCAAGCTAACCTTGGAAAAAATTCA
GGACTATCTGAGTCAATTTCGCCAAATCAAGCGAAAGACCATCGAGGCAGTCACTTATCCGATTATACTTTTGGGTTTTC
TAGTGGTTATCATGCTAGGCTTGCGTCATTACCTAATCCCTCAGCTAGAGAGTCAAAATACCTTGACTGACTTGTTGCTT
CATTTGCCTCATTATTTCTTAGGTTTTTGTTTGCTTGTGCTGTTGCTAATTGGCTCTTTTTACCTATATGCCAAGTCCTG
TAGTCGGCTAAAACTATTTAGTCAGCTGAGCTATTATCCTATCATTGGGTCCTTATTGCGGCAATATTTGACAGCCTACT
ATGCTAGAGAATGGGGCAACCTCATCGGACAAGGCTTAGAATTAATCACCATTTTAGAGATGATGTCAAACGAAAAGTCA
CAGCTCATGCGAGAGCTTGCCAAGGATATCAAGCAGAGTCTACTAGCTGGCCAATCCTTTCATCAAAGGGTTGCAGCTTA
TCCCTTTTTTAAAAAGGAGCTAAGCCTAATGATTGAATATGGTGACATCAAATCAAAGCTTGGTCAGGAATTAGATATCT
ATTCCCAAGAAAGCTGGGAGACCTTTTTTAGTCAGCTTAATCGGGCAACACAATGGATCCAGCCGATTATTTTTTTAGTG
GTTGCTGTGGTTATTGTGATGATTTATGCTGCTATTTTATTACCAATTTATCAACAGATGGGAGATGTTTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(29-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.982

98.547

0.532
  comYB Streptococcus mutans UA159

53.982

98.547

0.532
  comYB Streptococcus gordonii str. Challis substr. CH1

52.059

98.837

0.515
  comGB/cglB Streptococcus mitis NCTC 12261

48.81

97.674

0.477
  comGB/cglB Streptococcus mitis SK321

49.249

96.802

0.477
  comGB/cglB Streptococcus pneumoniae Rx1

48.649

96.802

0.471
  comGB/cglB Streptococcus pneumoniae D39

48.649

96.802

0.471
  comGB/cglB Streptococcus pneumoniae R6

48.649

96.802

0.471
  comGB/cglB Streptococcus pneumoniae TIGR4

48.649

96.802

0.471
  comGB Lactococcus lactis subsp. cremoris KW2

46.933

94.767

0.445

Multiple sequence alignment