Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   A6J85_RS04915 Genome accession   NZ_CP020450
Coordinates   975716..976654 (+) Length   312 a.a.
NCBI ID   WP_046164736.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 970716..981654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS04905 (A6J85_04850) rpoC 971346..974993 (+) 3648 WP_082307343.1 DNA-directed RNA polymerase subunit beta' -
  A6J85_RS04910 (A6J85_04855) - 975244..975603 (+) 360 WP_008810065.1 DUF1033 family protein -
  A6J85_RS04915 (A6J85_04860) comYA 975716..976654 (+) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  A6J85_RS04920 (A6J85_04865) comYB 976587..977621 (+) 1035 WP_105165110.1 competence type IV pilus assembly protein ComGB Machinery gene
  A6J85_RS04925 (A6J85_04870) comYC 977618..977935 (+) 318 WP_045634162.1 competence type IV pilus major pilin ComGC Machinery gene
  A6J85_RS04930 (A6J85_04875) comYD 977895..978323 (+) 429 WP_045634161.1 competence type IV pilus minor pilin ComGD Machinery gene
  A6J85_RS04935 (A6J85_04880) comGE/cglE 978295..978588 (+) 294 WP_045634160.1 competence type IV pilus minor pilin ComGE Machinery gene
  A6J85_RS04940 (A6J85_04885) comGF/cglF 978572..979009 (+) 438 WP_061596806.1 competence type IV pilus minor pilin ComGF Machinery gene
  A6J85_RS04945 (A6J85_04890) comGG 978990..979421 (+) 432 WP_223351938.1 competence type IV pilus minor pilin ComGG -
  A6J85_RS04950 (A6J85_04895) comYH 979452..980405 (+) 954 WP_048777263.1 class I SAM-dependent methyltransferase Machinery gene
  A6J85_RS04955 (A6J85_04900) - 980455..981645 (+) 1191 WP_048777262.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35828.81 Da        Isoelectric Point: 5.4496

>NTDB_id=223173 A6J85_RS04915 WP_046164736.1 975716..976654(+) (comYA) [Streptococcus gordonii strain FDAARGOS_257]
MVQKIAQAIVRQAKEECAQDIYFVPKDDCYELYMRIGDERRFIQTYDFDQLAAVISHFKFLAGMNVGEKRRSQLGSCDYR
YDDKETSIRLSTVGDYRGYESLVIRLLHDEETELKFWFTHFPEFREKFKDRGLYLFSGPVGSGKTTLMHQLAQLKFKGQQ
VMSIEDPVEIKQEDMLQLQLNETIGLTYESLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIPGVY
ERLLELGVSEEELKIVLQGICYQRLIGGGGVIDFASNNYQEHEPTVWNQQIDQLLAAGHIHPEQAEAEKIRN

Nucleotide


Download         Length: 939 bp        

>NTDB_id=223173 A6J85_RS04915 WP_046164736.1 975716..976654(+) (comYA) [Streptococcus gordonii strain FDAARGOS_257]
ATGGTTCAAAAAATTGCCCAGGCGATTGTCCGGCAGGCTAAGGAAGAGTGTGCTCAGGATATTTATTTTGTACCCAAGGA
TGATTGCTATGAACTTTATATGCGGATTGGTGATGAACGACGCTTCATACAGACTTATGATTTTGACCAATTAGCCGCTG
TGATTAGTCATTTTAAATTTTTAGCTGGGATGAATGTAGGAGAAAAACGTCGCAGTCAGCTGGGATCCTGTGATTATCGT
TATGATGATAAGGAAACATCAATTCGTCTGTCAACTGTAGGTGATTATCGTGGATATGAAAGTTTGGTTATTCGACTTTT
GCACGATGAAGAGACAGAATTGAAGTTTTGGTTTACTCATTTTCCTGAGTTTAGAGAGAAGTTTAAGGATCGAGGACTGT
ATCTTTTTTCGGGACCAGTAGGGAGTGGCAAGACCACTCTCATGCATCAATTAGCTCAGCTAAAATTTAAGGGTCAGCAG
GTTATGTCCATTGAGGATCCTGTTGAAATCAAGCAAGAGGATATGCTTCAGCTACAGCTGAATGAAACGATTGGTCTGAC
CTATGAAAGTCTAATTAAGCTTTCCCTGCGTCACCGTCCGGACTTGCTGATTATTGGAGAAATTCGAGATAGTGAAACTG
CTAGAGCTGTGGTTCGAGCTAGCTTGACGGGAGCTACAGTTTTTTCAACGATTCATGCTAAAAGCATTCCTGGTGTTTAC
GAACGCTTATTGGAATTAGGTGTTAGCGAGGAGGAGTTGAAAATTGTTTTACAGGGTATTTGCTATCAACGCTTGATTGG
GGGAGGAGGTGTGATAGACTTTGCCAGCAACAACTACCAAGAACACGAGCCGACCGTCTGGAATCAGCAGATTGATCAGC
TTCTTGCAGCAGGACATATCCATCCTGAGCAAGCAGAAGCAGAAAAAATTAGGAACTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

99.359

100

0.994
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

78.065

99.359

0.776
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

77.742

99.359

0.772
  comGA/cglA/cilD Streptococcus pneumoniae D39

77.742

99.359

0.772
  comGA/cglA/cilD Streptococcus pneumoniae R6

77.742

99.359

0.772
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

77.742

99.359

0.772
  comYA Streptococcus mutans UA159

67.093

100

0.673
  comYA Streptococcus mutans UA140

67.093

100

0.673
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.064

100

0.651
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

100

0.548

Multiple sequence alignment