Detailed information NTG0223178

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: A6J85_RS04940
• Genome accession: NZ_CP020450
• Coordinates: 978572..979009 (+)
• Length: 145 a.a.
• NCBI ID: WP_061596806.1
• Uniprot ID: A0AB35FWE1
• Organism: Streptococcus gordonii strain FDAARGOS_257
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 973572..984009

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J85_RS04910 (A6J85_04855)	-	975244..975603 (+)	360	WP_008810065.1	DUF1033 family protein	-
A6J85_RS04915 (A6J85_04860)	comYA	975716..976654 (+)	939	WP_046164736.1	competence type IV pilus ATPase ComGA	Machinery gene
A6J85_RS04920 (A6J85_04865)	comYB	976587..977621 (+)	1035	WP_105165110.1	competence type IV pilus assembly protein ComGB	Machinery gene
A6J85_RS04925 (A6J85_04870)	comYC	977618..977935 (+)	318	WP_045634162.1	competence type IV pilus major pilin ComGC	Machinery gene
A6J85_RS04930 (A6J85_04875)	comYD	977895..978323 (+)	429	WP_045634161.1	competence type IV pilus minor pilin ComGD	Machinery gene
A6J85_RS04935 (A6J85_04880)	comGE/cglE	978295..978588 (+)	294	WP_045634160.1	competence type IV pilus minor pilin ComGE	Machinery gene
A6J85_RS04940 (A6J85_04885)	comGF/cglF	978572..979009 (+)	438	WP_061596806.1	competence type IV pilus minor pilin ComGF	Machinery gene
A6J85_RS04945 (A6J85_04890)	comGG	978990..979421 (+)	432	WP_223351938.1	competence type IV pilus minor pilin ComGG	-
A6J85_RS04950 (A6J85_04895)	comYH	979452..980405 (+)	954	WP_048777263.1	class I SAM-dependent methyltransferase	Machinery gene
A6J85_RS04955 (A6J85_04900)	-	980455..981645 (+)	1191	WP_048777262.1	acetate kinase	-
A6J85_RS04960 (A6J85_04905)	-	981693..982358 (+)	666	WP_048777261.1	CPBP family intramembrane glutamic endopeptidase	-
A6J85_RS04965 (A6J85_04910)	folP	982436..983401 (+)	966	WP_082307344.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16574.04 Da
• Isoelectric Point: 6.9913

>NTDB_id=223178 A6J85_RS04940 WP_061596806.1 978572..979009(+) (comGF/cglF) [Streptococcus gordonii strain FDAARGOS_257]
MLKKGKVGAFTLLEALVALLVISGGLLVFQAMTKLLASEIQYQEQTKAKEWLLFADQLDAELSRSHFEKVEQNKLYVKQD
GKSIAFGKSKSDDFRKTDANGRGYQPMIYGLEAAQIHKEGQIVHLHLQFKDGLEREYIYRVEEEH

Nucleotide

• Length: 438 bp

>NTDB_id=223178 A6J85_RS04940 WP_061596806.1 978572..979009(+) (comGF/cglF) [Streptococcus gordonii strain FDAARGOS_257]
ATGTTGAAAAAAGGTAAAGTAGGAGCTTTTACCCTGCTGGAAGCATTAGTGGCCCTCTTGGTTATCAGTGGTGGCCTCTT
GGTTTTTCAAGCTATGACTAAGCTCCTAGCCAGTGAGATTCAGTATCAAGAGCAAACTAAGGCCAAGGAATGGCTCTTGT
TTGCGGACCAGTTAGATGCAGAATTATCCCGGAGCCATTTTGAAAAAGTCGAGCAAAATAAGCTTTATGTCAAACAAGAT
GGCAAGTCGATTGCATTTGGTAAGTCTAAAAGCGATGATTTTCGAAAGACGGATGCGAATGGCCGTGGTTATCAACCCAT
GATTTATGGCTTAGAAGCTGCTCAAATACATAAAGAAGGTCAGATAGTTCATTTGCATCTGCAGTTTAAGGACGGCTTAG
AAAGAGAGTACATCTATCGTGTTGAAGAAGAACATTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	68.31	97.931	0.669
comGF/cglF	Streptococcus pneumoniae D39	68.31	97.931	0.669
comGF/cglF	Streptococcus pneumoniae R6	68.31	97.931	0.669
comGF/cglF	Streptococcus pneumoniae TIGR4	68.31	97.931	0.669
comGF/cglF	Streptococcus mitis NCTC 12261	68.085	97.241	0.662
comGF/cglF	Streptococcus mitis SK321	66.667	97.241	0.648
comYF	Streptococcus mutans UA140	47.887	97.931	0.469
comYF	Streptococcus mutans UA159	47.183	97.931	0.462
comGF	Lactococcus lactis subsp. cremoris KW2	42.857	96.552	0.414