Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   A6J85_RS04935 Genome accession   NZ_CP020450
Coordinates   978295..978588 (+) Length   97 a.a.
NCBI ID   WP_045634160.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 973295..983588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS04910 (A6J85_04855) - 975244..975603 (+) 360 WP_008810065.1 DUF1033 family protein -
  A6J85_RS04915 (A6J85_04860) comYA 975716..976654 (+) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  A6J85_RS04920 (A6J85_04865) comYB 976587..977621 (+) 1035 WP_105165110.1 competence type IV pilus assembly protein ComGB Machinery gene
  A6J85_RS04925 (A6J85_04870) comYC 977618..977935 (+) 318 WP_045634162.1 competence type IV pilus major pilin ComGC Machinery gene
  A6J85_RS04930 (A6J85_04875) comYD 977895..978323 (+) 429 WP_045634161.1 competence type IV pilus minor pilin ComGD Machinery gene
  A6J85_RS04935 (A6J85_04880) comGE/cglE 978295..978588 (+) 294 WP_045634160.1 competence type IV pilus minor pilin ComGE Machinery gene
  A6J85_RS04940 (A6J85_04885) comGF/cglF 978572..979009 (+) 438 WP_061596806.1 competence type IV pilus minor pilin ComGF Machinery gene
  A6J85_RS04945 (A6J85_04890) comGG 978990..979421 (+) 432 WP_223351938.1 competence type IV pilus minor pilin ComGG -
  A6J85_RS04950 (A6J85_04895) comYH 979452..980405 (+) 954 WP_048777263.1 class I SAM-dependent methyltransferase Machinery gene
  A6J85_RS04955 (A6J85_04900) - 980455..981645 (+) 1191 WP_048777262.1 acetate kinase -
  A6J85_RS04960 (A6J85_04905) - 981693..982358 (+) 666 WP_048777261.1 CPBP family intramembrane glutamic endopeptidase -
  A6J85_RS04965 (A6J85_04910) folP 982436..983401 (+) 966 WP_082307344.1 dihydropteroate synthase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10898.80 Da        Isoelectric Point: 10.0864

>NTDB_id=223177 A6J85_RS04935 WP_045634160.1 978295..978588(+) (comGE/cglE) [Streptococcus gordonii strain FDAARGOS_257]
MANLRKRQIKGTILLEALLALGVFAVIASLLLGQITQSRKEAAAILEKEEVLRVAQMALQTGQDHLSLNGIEIRIQRTKD
QIRVFHQGEELIDVEKR

Nucleotide


Download         Length: 294 bp        

>NTDB_id=223177 A6J85_RS04935 WP_045634160.1 978295..978588(+) (comGE/cglE) [Streptococcus gordonii strain FDAARGOS_257]
ATGGCAAATTTAAGAAAACGACAAATTAAAGGGACCATCTTACTGGAAGCCTTACTGGCTTTGGGAGTTTTTGCTGTAAT
TGCAAGCTTGTTACTAGGTCAAATCACGCAATCGCGTAAAGAAGCAGCTGCCATTTTAGAAAAAGAGGAGGTCCTGCGGG
TGGCCCAGATGGCCCTCCAAACAGGGCAGGACCATCTTTCTTTAAATGGTATTGAAATTCGTATCCAGAGAACGAAGGAT
CAGATTCGAGTGTTCCATCAGGGAGAGGAGTTGATTGATGTTGAAAAAAGGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

53.763

95.876

0.515
  comGE/cglE Streptococcus pneumoniae D39

53.763

95.876

0.515
  comGE/cglE Streptococcus pneumoniae R6

53.763

95.876

0.515
  comGE/cglE Streptococcus pneumoniae TIGR4

53.763

95.876

0.515
  comGE/cglE Streptococcus mitis NCTC 12261

51.613

95.876

0.495
  comGE/cglE Streptococcus mitis SK321

51.613

95.876

0.495
  comYE Streptococcus mutans UA140

41.237

100

0.412
  comYE Streptococcus mutans UA159

41.237

100

0.412

Multiple sequence alignment