Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   A6J85_RS04920 Genome accession   NZ_CP020450
Coordinates   976587..977621 (+) Length   344 a.a.
NCBI ID   WP_105165110.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 971587..982621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS04910 (A6J85_04855) - 975244..975603 (+) 360 WP_008810065.1 DUF1033 family protein -
  A6J85_RS04915 (A6J85_04860) comYA 975716..976654 (+) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  A6J85_RS04920 (A6J85_04865) comYB 976587..977621 (+) 1035 WP_105165110.1 competence type IV pilus assembly protein ComGB Machinery gene
  A6J85_RS04925 (A6J85_04870) comYC 977618..977935 (+) 318 WP_045634162.1 competence type IV pilus major pilin ComGC Machinery gene
  A6J85_RS04930 (A6J85_04875) comYD 977895..978323 (+) 429 WP_045634161.1 competence type IV pilus minor pilin ComGD Machinery gene
  A6J85_RS04935 (A6J85_04880) comGE/cglE 978295..978588 (+) 294 WP_045634160.1 competence type IV pilus minor pilin ComGE Machinery gene
  A6J85_RS04940 (A6J85_04885) comGF/cglF 978572..979009 (+) 438 WP_061596806.1 competence type IV pilus minor pilin ComGF Machinery gene
  A6J85_RS04945 (A6J85_04890) comGG 978990..979421 (+) 432 WP_223351938.1 competence type IV pilus minor pilin ComGG -
  A6J85_RS04950 (A6J85_04895) comYH 979452..980405 (+) 954 WP_048777263.1 class I SAM-dependent methyltransferase Machinery gene
  A6J85_RS04955 (A6J85_04900) - 980455..981645 (+) 1191 WP_048777262.1 acetate kinase -
  A6J85_RS04960 (A6J85_04905) - 981693..982358 (+) 666 WP_048777261.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 38990.12 Da        Isoelectric Point: 8.8858

>NTDB_id=223174 A6J85_RS04920 WP_105165110.1 976587..977621(+) (comYB) [Streptococcus gordonii strain FDAARGOS_257]
MISFLQQDISILSKQKQKKLGTSKQKQVIELFNNLFSSGFHLAETVDFLGRSALLEKNYVQQMRHGLANGQAFSEIMASL
GFSDAVVTQLSLAELHGNLSLALLKIEEYLDNLAKVKKKLIEVATYPMMLLGFLVLIMMGLRNYLLPQLSSQNFATQLIG
HLPTIFLLSVLMLLGLTGAIYLIFKGQKRIPVYSFLARLPFVGSFVKIYLTAYYAREWGNMIGQGLELSQIFQIMQEQLS
VLFQEIGQDLGQALQNGQEFSDKIASYPFLKKELSLIIEYGEVKSKLGSELEIYALKTWEEFFGRVNRTMNLIQPLVFVF
VALMIVLLYAAMLLPLYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=223174 A6J85_RS04920 WP_105165110.1 976587..977621(+) (comYB) [Streptococcus gordonii strain FDAARGOS_257]
TTGATCAGCTTCTTGCAGCAGGACATATCCATCCTGAGCAAGCAGAAGCAGAAAAAATTAGGAACTAGCAAGCAAAAGCA
GGTCATTGAACTGTTTAATAATTTATTCTCTAGCGGTTTTCACTTGGCTGAGACTGTGGACTTTTTAGGTCGAAGCGCTC
TTTTGGAGAAGAACTATGTTCAGCAAATGCGTCATGGCCTAGCTAATGGGCAAGCATTTTCAGAGATTATGGCTAGTCTA
GGTTTTTCTGATGCGGTAGTAACCCAGCTGTCATTGGCTGAGTTACATGGGAATTTATCGCTTGCCTTGCTAAAAATAGA
GGAATATCTGGATAATCTTGCGAAGGTAAAAAAGAAGTTAATTGAAGTAGCGACCTATCCCATGATGCTTCTCGGCTTTT
TGGTATTGATTATGATGGGCTTGAGAAATTATTTATTACCCCAACTCAGCAGTCAAAATTTTGCAACGCAACTCATTGGT
CATTTGCCGACTATTTTTCTACTATCTGTCTTAATGTTACTTGGATTAACAGGAGCGATTTATCTGATTTTCAAAGGCCA
GAAACGGATCCCTGTATACTCTTTCTTAGCTCGCCTGCCTTTTGTTGGATCCTTTGTAAAGATTTACCTAACCGCCTATT
ATGCGCGTGAATGGGGCAATATGATTGGACAAGGTTTGGAGCTCAGTCAGATTTTTCAGATTATGCAAGAGCAACTCTCG
GTTTTATTTCAGGAAATTGGTCAGGATTTGGGTCAAGCCTTACAAAACGGTCAAGAATTTTCAGATAAAATTGCTTCGTA
TCCTTTTTTAAAAAAAGAATTGTCTCTAATCATCGAATACGGGGAAGTCAAATCTAAGCTGGGAAGCGAACTAGAAATCT
ATGCTCTTAAGACTTGGGAAGAATTTTTTGGTAGGGTCAATCGGACCATGAATCTGATTCAGCCCCTAGTCTTTGTCTTT
GTAGCCTTGATGATTGTCTTATTGTATGCGGCAATGCTATTGCCCCTTTATCAAAATATGGAGGTTCATCTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(30-147)

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

97.965

100

0.98
  comGB/cglB Streptococcus mitis NCTC 12261

72.434

99.128

0.718
  comGB/cglB Streptococcus mitis SK321

72.321

97.674

0.706
  comGB/cglB Streptococcus pneumoniae TIGR4

70.833

97.674

0.692
  comGB/cglB Streptococcus pneumoniae R6

70.833

97.674

0.692
  comGB/cglB Streptococcus pneumoniae Rx1

70.833

97.674

0.692
  comGB/cglB Streptococcus pneumoniae D39

70.833

97.674

0.692
  comYB Streptococcus mutans UA140

59.767

99.709

0.596
  comYB Streptococcus mutans UA159

59.475

99.709

0.593
  comGB Lactococcus lactis subsp. cremoris KW2

51.335

97.965

0.503

Multiple sequence alignment