Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   BRL61_RS08040 Genome accession   NZ_CP019117
Coordinates   1606646..1606957 (-) Length   103 a.a.
NCBI ID   WP_000472257.1    Uniprot ID   A0A115HMG3
Organism   Staphylococcus aureus strain SJTUF_J27     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1601646..1611957
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BRL61_RS08005 (BRL61_08000) gcvPA 1602148..1603494 (-) 1347 WP_000019697.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  BRL61_RS08010 (BRL61_08005) gcvT 1603514..1604605 (-) 1092 WP_000093347.1 glycine cleavage system aminomethyltransferase GcvT -
  BRL61_RS08015 (BRL61_08010) - 1604764..1605288 (-) 525 WP_001015125.1 shikimate kinase -
  BRL61_RS08020 (BRL61_08015) - 1605278..1605424 (-) 147 WP_001789879.1 hypothetical protein -
  BRL61_RS08025 (BRL61_08020) comGF 1605521..1606018 (-) 498 WP_001794328.1 competence type IV pilus minor pilin ComGF Machinery gene
  BRL61_RS08030 (BRL61_08025) comGE 1605936..1606235 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  BRL61_RS08035 (BRL61_08030) comGD 1606222..1606668 (-) 447 WP_001791207.1 competence type IV pilus minor pilin ComGD Machinery gene
  BRL61_RS08040 (BRL61_08035) comGC 1606646..1606957 (-) 312 WP_000472257.1 competence type IV pilus major pilin ComGC Machinery gene
  BRL61_RS08045 (BRL61_08040) comGB 1606971..1608041 (-) 1071 WP_053865724.1 competence type IV pilus assembly protein ComGB Machinery gene
  BRL61_RS08050 (BRL61_08045) comGA 1608013..1608987 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  BRL61_RS08055 (BRL61_08050) - 1609039..1609662 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  BRL61_RS08060 (BRL61_08055) - 1609659..1609988 (-) 330 WP_053865723.1 MTH1187 family thiamine-binding protein -
  BRL61_RS08065 (BRL61_08060) - 1609988..1610974 (-) 987 WP_000161314.1 ROK family glucokinase -
  BRL61_RS08070 (BRL61_08065) - 1610971..1611174 (-) 204 WP_000087561.1 YqgQ family protein -

Sequence


Protein


Download         Length: 103 a.a.        Molecular weight: 11373.39 Da        Isoelectric Point: 7.8600

>NTDB_id=213230 BRL61_RS08040 WP_000472257.1 1606646..1606957(-) (comGC) [Staphylococcus aureus strain SJTUF_J27]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEEQKTCKSGETITISNGEAVAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=213230 BRL61_RS08040 WP_000472257.1 1606646..1606957(-) (comGC) [Staphylococcus aureus strain SJTUF_J27]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGAGCAAAAGACATGTAAATCAGGAGAGACAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A115HMG3

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus N315

99.029

100

0.99

  comGC Staphylococcus aureus MW2

99.029

100

0.99

  comGC/cglC Streptococcus mitis SK321

48.039

99.029

0.476

  comGC/cglC Streptococcus pneumoniae R6

47.059

99.029

0.466

  comGC/cglC Streptococcus pneumoniae D39

47.059

99.029

0.466

  comGC/cglC Streptococcus pneumoniae TIGR4

47.059

99.029

0.466

  comGC/cglC Streptococcus pneumoniae Rx1

47.059

99.029

0.466

  comGC/cglC Streptococcus mitis NCTC 12261

52.326

83.495

0.437

  comYC Streptococcus gordonii str. Challis substr. CH1

42.857

95.146

0.408

  comYC Streptococcus suis isolate S10

50

75.728

0.379

  comYC Streptococcus mutans UA140

50

73.786

0.369

  comYC Streptococcus mutans UA159

50

73.786

0.369

  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369

  comGC Lactococcus lactis subsp. cremoris KW2

46.341

79.612

0.369


Multiple sequence alignment