Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   BSR19_RS09740 Genome accession   NZ_CP018187
Coordinates   2108811..2109752 (-) Length   313 a.a.
NCBI ID   WP_002885658.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2103811..2114752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS09700 (BSR19_09830) - 2103886..2105079 (-) 1194 WP_138261572.1 acetate kinase -
  BSR19_RS09705 (BSR19_09835) comYH 2105136..2106092 (-) 957 WP_138261573.1 class I SAM-dependent methyltransferase Machinery gene
  BSR19_RS09710 (BSR19_09840) comGG 2106137..2106454 (-) 318 WP_156247046.1 competence type IV pilus minor pilin ComGG -
  BSR19_RS09715 (BSR19_09845) comYF 2106432..2106869 (-) 438 WP_045769383.1 competence type IV pilus minor pilin ComGF Machinery gene
  BSR19_RS09720 (BSR19_09850) comGE 2106856..2107086 (-) 231 WP_002887015.1 competence type IV pilus minor pilin ComGE -
  BSR19_RS09725 (BSR19_09855) comYD 2107118..2107546 (-) 429 WP_014632541.1 competence type IV pilus minor pilin ComGD Machinery gene
  BSR19_RS09730 (BSR19_09860) comYC 2107506..2107832 (-) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  BSR19_RS09735 (BSR19_09865) comYB 2107829..2108929 (-) 1101 WP_156247047.1 competence type IV pilus assembly protein ComGB Machinery gene
  BSR19_RS09740 (BSR19_09870) comYA 2108811..2109752 (-) 942 WP_002885658.1 competence type IV pilus ATPase ComGA Machinery gene
  BSR19_RS09745 (BSR19_09875) - 2109834..2110196 (-) 363 WP_002887019.1 DUF1033 family protein -
  BSR19_RS09750 (BSR19_09880) rpoC 2110359..2113997 (-) 3639 WP_037603707.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35283.27 Da        Isoelectric Point: 5.4492

>NTDB_id=206880 BSR19_RS09740 WP_002885658.1 2108811..2109752(-) (comYA) [Streptococcus salivarius strain ICDC2]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVQQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=206880 BSR19_RS09740 WP_002885658.1 2108811..2109752(-) (comYA) [Streptococcus salivarius strain ICDC2]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCAGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTATCAACCGTTGGGGATTATCGTGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTGGTGTATTGGAATCAAGGAATCCAGCCGATTATGGATGCTTTGGATTATCGTGGCT
TGTATCTCTTTGCAGGTCCCGTAGGTTCTGGAAAGACTACGCTTATGCATGAATTGGTTCAGGAGCGTTTTAAGGGACAG
CAGGTGATTTCGATTGAAGATCCTGTGGAAATTAAACAGGATAATGTCTTGCAACTCCAGGTAAATCAGGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTACGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACAGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTCGGTGTAGATAAGTCTGAGTTGGATAATGCTCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTCAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.176

100

0.652
  comYA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.309

99.361

0.639
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361

Multiple sequence alignment