Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   SPG_1968 Genome accession   CP001015
Coordinates   1863578..1864519 (-) Length   313 a.a.
NCBI ID   ACF55208.1    Uniprot ID   -
Organism   Streptococcus pneumoniae G54     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1858578..1869519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG_1959 comYH 1859064..1860017 (-) 954 ACF56004.1 conserved hypothetical protein Machinery gene
  SPG_1960 - 1860078..1860458 (-) 381 ACF56765.1 hypothetical protein -
  SPG_1961 - 1860490..1860672 (-) 183 ACF55149.1 conserved hypothetical protein -
  SPG_1962 comGG/cglG 1860809..1861222 (-) 414 ACF54761.1 conserved hypothetical protein Machinery gene
  SPG_1963 comGF/cglF 1861200..1861661 (-) 462 ACF55334.1 conserved hypothetical protein Machinery gene
  SPG_1964 comGE/cglE 1861624..1861926 (-) 303 ACF56096.1 hypothetical protein Machinery gene
  SPG_1965 comGD/cglD 1861889..1862293 (-) 405 ACF56539.1 competence protein CglD Machinery gene
  SPG_1966 comGC/cglC 1862286..1862612 (-) 327 ACF55098.1 competence protein CglC Machinery gene
  SPG_1967 comGB/cglB 1862614..1863630 (-) 1017 ACF55582.1 competence protein CglB Machinery gene
  SPG_1968 comGA/cglA/cilD 1863578..1864519 (-) 942 ACF55208.1 competence protein CglA Machinery gene
  SPG_1969 - 1864595..1864960 (-) 366 ACF55572.1 conserved hypothetical protein -
  SPG_1970 - 1865111..1866169 (-) 1059 ACF56524.1 alcohol dehydrogenase, zinc-containing -
  SPG_1971 nagA 1866332..1867483 (-) 1152 ACF55866.1 N-acetylglucosamine-6-phosphate deacetylase -
  SPG_1972 - 1867636..1869453 (-) 1818 ACF54777.1 putative acyltransferase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35587.57 Da        Isoelectric Point: 6.0083

>NTDB_id=20238 SPG_1968 ACF55208.1 1863578..1864519(-) (comGA/cglA/cilD) [Streptococcus pneumoniae G54]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=20238 SPG_1968 ACF55208.1 1863578..1864519(-) (comGA/cglA/cilD) [Streptococcus pneumoniae G54]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGCTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCCAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGTCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACATCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

98.403

100

0.984
  comGA/cglA/cilD Streptococcus pneumoniae D39

98.403

100

0.984
  comGA/cglA/cilD Streptococcus pneumoniae R6

98.403

100

0.984
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

98.403

100

0.984
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.805

100

0.968
  comYA Streptococcus gordonii str. Challis substr. CH1

77.742

99.042

0.77
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.912

86.901

0.364

Multiple sequence alignment