Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   SPG_1967 Genome accession   CP001015
Coordinates   1862614..1863630 (-) Length   338 a.a.
NCBI ID   ACF55582.1    Uniprot ID   -
Organism   Streptococcus pneumoniae G54     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1857614..1868630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPG_1957 - 1857691..1857822 (-) 132 ACF54788.1 conserved hypothetical protein -
  SPG_1958 ackA 1857823..1859013 (-) 1191 ACF56573.1 acetate kinase -
  SPG_1959 comYH 1859064..1860017 (-) 954 ACF56004.1 conserved hypothetical protein Machinery gene
  SPG_1960 - 1860078..1860458 (-) 381 ACF56765.1 hypothetical protein -
  SPG_1961 - 1860490..1860672 (-) 183 ACF55149.1 conserved hypothetical protein -
  SPG_1962 comGG/cglG 1860809..1861222 (-) 414 ACF54761.1 conserved hypothetical protein Machinery gene
  SPG_1963 comGF/cglF 1861200..1861661 (-) 462 ACF55334.1 conserved hypothetical protein Machinery gene
  SPG_1964 comGE/cglE 1861624..1861926 (-) 303 ACF56096.1 hypothetical protein Machinery gene
  SPG_1965 comGD/cglD 1861889..1862293 (-) 405 ACF56539.1 competence protein CglD Machinery gene
  SPG_1966 comGC/cglC 1862286..1862612 (-) 327 ACF55098.1 competence protein CglC Machinery gene
  SPG_1967 comGB/cglB 1862614..1863630 (-) 1017 ACF55582.1 competence protein CglB Machinery gene
  SPG_1968 comGA/cglA/cilD 1863578..1864519 (-) 942 ACF55208.1 competence protein CglA Machinery gene
  SPG_1969 - 1864595..1864960 (-) 366 ACF55572.1 conserved hypothetical protein -
  SPG_1970 - 1865111..1866169 (-) 1059 ACF56524.1 alcohol dehydrogenase, zinc-containing -
  SPG_1971 nagA 1866332..1867483 (-) 1152 ACF55866.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38524.56 Da        Isoelectric Point: 9.6162

>NTDB_id=20237 SPG_1967 ACF55582.1 1862614..1863630(-) (comGB/cglB) [Streptococcus pneumoniae G54]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LVMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=20237 SPG_1967 ACF55582.1 1862614..1863630(-) (comGB/cglB) [Streptococcus pneumoniae G54]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTTCCTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGTCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae D39

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae R6

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae TIGR4

98.225

100

0.982
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comGB/cglB Streptococcus mitis NCTC 12261

93.787

100

0.938
  comYB Streptococcus gordonii str. Challis substr. CH1

70.536

99.408

0.701
  comYB Streptococcus mutans UA140

57.595

93.491

0.538
  comYB Streptococcus mutans UA159

57.595

93.491

0.538
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503

Multiple sequence alignment