Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   WH25_RS10375 Genome accession   NZ_CP017295
Coordinates   2162802..2163119 (-) Length   105 a.a.
NCBI ID   WP_012130940.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2157802..2168119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS10340 (WH25_10340) - 2158379..2159044 (-) 666 WP_046164730.1 CPBP family intramembrane glutamic endopeptidase -
  WH25_RS10345 (WH25_10345) - 2159092..2160282 (-) 1191 WP_045634156.1 acetate kinase -
  WH25_RS10350 (WH25_10350) comYH 2160332..2161285 (-) 954 WP_046164731.1 class I SAM-dependent methyltransferase Machinery gene
  WH25_RS10355 (WH25_10355) comGG 2161316..2161747 (-) 432 WP_231108792.1 competence type IV pilus minor pilin ComGG -
  WH25_RS10360 (WH25_10360) comGF/cglF 2161728..2162165 (-) 438 WP_046164732.1 competence type IV pilus minor pilin ComGF Machinery gene
  WH25_RS10365 (WH25_10365) comGE/cglE 2162149..2162442 (-) 294 WP_046164733.1 competence type IV pilus minor pilin ComGE Machinery gene
  WH25_RS10370 (WH25_10370) comYD 2162414..2162842 (-) 429 WP_069097080.1 competence type IV pilus minor pilin ComGD Machinery gene
  WH25_RS10375 (WH25_10375) comYC 2162802..2163119 (-) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  WH25_RS10380 (WH25_10380) comYB 2163116..2164150 (-) 1035 WP_046164735.1 competence type IV pilus assembly protein ComGB Machinery gene
  WH25_RS10385 (WH25_10385) comYA 2164083..2165021 (-) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  WH25_RS10390 (WH25_10390) - 2165123..2165491 (-) 369 WP_046164737.1 DUF1033 family protein -

Sequence


Protein


Download         Length: 105 a.a.        Molecular weight: 11461.38 Da        Isoelectric Point: 9.9223

>NTDB_id=197451 WH25_RS10375 WP_012130940.1 2162802..2163119(-) (comYC) [Streptococcus gordonii strain IE35]
MNKLKKLRVKAFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVSDTGNAAVVKVVESQAELYELKNTGDQATLSKLVAAGN
ISQKQADSYKAYYGKNNSETQAVAN

Nucleotide


Download         Length: 318 bp        

>NTDB_id=197451 WH25_RS10375 WP_012130940.1 2162802..2163119(-) (comYC) [Streptococcus gordonii strain IE35]
ATGAACAAATTAAAAAAATTACGTGTGAAAGCTTTTACTTTGGTGGAAATGTTAGTCGTCCTTCTGATCATCAGTGTCCT
TATGCTCTTATTCGTCCCTAATCTAACCAAGCAAAAAGAGGCTGTTTCGGATACTGGAAATGCTGCGGTGGTTAAGGTAG
TTGAGAGCCAGGCTGAGCTCTATGAACTCAAAAATACAGGAGATCAAGCAACCCTCAGCAAACTAGTCGCAGCTGGGAAC
ATTAGTCAAAAGCAAGCAGACTCTTACAAGGCTTATTATGGTAAGAACAATAGTGAGACTCAGGCAGTTGCCAATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

100

100

1

  comYC Streptococcus mutans UA140

71.429

100

0.714

  comYC Streptococcus mutans UA159

71.429

100

0.714

  comGC/cglC Streptococcus mitis NCTC 12261

69.524

100

0.695

  comGC/cglC Streptococcus mitis SK321

68.932

98.095

0.676

  comGC/cglC Streptococcus pneumoniae Rx1

67.961

98.095

0.667

  comGC/cglC Streptococcus pneumoniae D39

67.961

98.095

0.667

  comGC/cglC Streptococcus pneumoniae TIGR4

67.961

98.095

0.667

  comGC/cglC Streptococcus pneumoniae R6

67.961

98.095

0.667

  comGC Lactococcus lactis subsp. cremoris KW2

59.794

92.381

0.552

  comYC Streptococcus suis isolate S10

61.798

84.762

0.524


Multiple sequence alignment