Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   WH25_RS10365 Genome accession   NZ_CP017295
Coordinates   2162149..2162442 (-) Length   97 a.a.
NCBI ID   WP_046164733.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2157149..2167442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS10335 (WH25_10335) folP 2157337..2158302 (-) 966 WP_046164729.1 dihydropteroate synthase -
  WH25_RS10340 (WH25_10340) - 2158379..2159044 (-) 666 WP_046164730.1 CPBP family intramembrane glutamic endopeptidase -
  WH25_RS10345 (WH25_10345) - 2159092..2160282 (-) 1191 WP_045634156.1 acetate kinase -
  WH25_RS10350 (WH25_10350) comYH 2160332..2161285 (-) 954 WP_046164731.1 class I SAM-dependent methyltransferase Machinery gene
  WH25_RS10355 (WH25_10355) comGG 2161316..2161747 (-) 432 WP_231108792.1 competence type IV pilus minor pilin ComGG -
  WH25_RS10360 (WH25_10360) comGF/cglF 2161728..2162165 (-) 438 WP_046164732.1 competence type IV pilus minor pilin ComGF Machinery gene
  WH25_RS10365 (WH25_10365) comGE/cglE 2162149..2162442 (-) 294 WP_046164733.1 competence type IV pilus minor pilin ComGE Machinery gene
  WH25_RS10370 (WH25_10370) comYD 2162414..2162842 (-) 429 WP_069097080.1 competence type IV pilus minor pilin ComGD Machinery gene
  WH25_RS10375 (WH25_10375) comYC 2162802..2163119 (-) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  WH25_RS10380 (WH25_10380) comYB 2163116..2164150 (-) 1035 WP_046164735.1 competence type IV pilus assembly protein ComGB Machinery gene
  WH25_RS10385 (WH25_10385) comYA 2164083..2165021 (-) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  WH25_RS10390 (WH25_10390) - 2165123..2165491 (-) 369 WP_046164737.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10943.95 Da        Isoelectric Point: 10.6470

>NTDB_id=197449 WH25_RS10365 WP_046164733.1 2162149..2162442(-) (comGE/cglE) [Streptococcus gordonii strain IE35]
MVNLRKRQIKGTILLEALLALGVFAVIASLLLGQITQSRKEAAAILEKEEVLRVAQMALQTGQDHLSLNGIEIRIQRTKD
QIRVFHQGKELMDVEKR

Nucleotide


Download         Length: 294 bp        

>NTDB_id=197449 WH25_RS10365 WP_046164733.1 2162149..2162442(-) (comGE/cglE) [Streptococcus gordonii strain IE35]
ATGGTAAATTTAAGAAAACGACAAATTAAAGGGACCATCTTACTGGAAGCCTTACTGGCTTTGGGAGTTTTTGCTGTAAT
TGCAAGCTTGTTACTAGGTCAAATCACGCAATCACGCAAAGAAGCAGCTGCCATTTTAGAAAAAGAGGAGGTCCTGCGGG
TGGCCCAGATGGCCCTCCAAACAGGGCAGGACCATCTTTCCTTAAATGGTATTGAAATTCGTATCCAGAGAACGAAGGAT
CAGATTCGAGTGTTCCATCAAGGAAAGGAGTTGATGGATGTTGAAAAAAGGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

52.688

95.876

0.505
  comGE/cglE Streptococcus pneumoniae D39

52.688

95.876

0.505
  comGE/cglE Streptococcus pneumoniae R6

52.688

95.876

0.505
  comGE/cglE Streptococcus pneumoniae TIGR4

52.688

95.876

0.505
  comGE/cglE Streptococcus mitis NCTC 12261

50.538

95.876

0.485
  comGE/cglE Streptococcus mitis SK321

50.538

95.876

0.485
  comYE Streptococcus mutans UA140

40.206

100

0.402
  comYE Streptococcus mutans UA159

40.206

100

0.402

Multiple sequence alignment