Detailed information NTG0197448

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: WH25_RS10360
• Genome accession: NZ_CP017295
• Coordinates: 2161728..2162165 (-)
• Length: 145 a.a.
• NCBI ID: WP_046164732.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain IE35
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2156728..2167165

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WH25_RS10335 (WH25_10335)	folP	2157337..2158302 (-)	966	WP_046164729.1	dihydropteroate synthase	-
WH25_RS10340 (WH25_10340)	-	2158379..2159044 (-)	666	WP_046164730.1	CPBP family intramembrane glutamic endopeptidase	-
WH25_RS10345 (WH25_10345)	-	2159092..2160282 (-)	1191	WP_045634156.1	acetate kinase	-
WH25_RS10350 (WH25_10350)	comYH	2160332..2161285 (-)	954	WP_046164731.1	class I SAM-dependent methyltransferase	Machinery gene
WH25_RS10355 (WH25_10355)	comGG	2161316..2161747 (-)	432	WP_231108792.1	competence type IV pilus minor pilin ComGG	-
WH25_RS10360 (WH25_10360)	comGF/cglF	2161728..2162165 (-)	438	WP_046164732.1	competence type IV pilus minor pilin ComGF	Machinery gene
WH25_RS10365 (WH25_10365)	comGE/cglE	2162149..2162442 (-)	294	WP_046164733.1	competence type IV pilus minor pilin ComGE	Machinery gene
WH25_RS10370 (WH25_10370)	comYD	2162414..2162842 (-)	429	WP_069097080.1	competence type IV pilus minor pilin ComGD	Machinery gene
WH25_RS10375 (WH25_10375)	comYC	2162802..2163119 (-)	318	WP_012130940.1	competence type IV pilus major pilin ComGC	Machinery gene
WH25_RS10380 (WH25_10380)	comYB	2163116..2164150 (-)	1035	WP_046164735.1	competence type IV pilus assembly protein ComGB	Machinery gene
WH25_RS10385 (WH25_10385)	comYA	2164083..2165021 (-)	939	WP_046164736.1	competence type IV pilus ATPase ComGA	Machinery gene
WH25_RS10390 (WH25_10390)	-	2165123..2165491 (-)	369	WP_046164737.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16533.03 Da
• Isoelectric Point: 6.7631

>NTDB_id=197448 WH25_RS10360 WP_046164732.1 2161728..2162165(-) (comGF/cglF) [Streptococcus gordonii strain IE35]
MLKKGKVGAFTLLEALVALLVISGGLLVFQAMTKLLASEIQLQEQTKAKEWLLFADQLDVELSRSHFEKVEQNKLYVKQD
GKSIAFGKSKSDDFRKTDANGHGYQPMIYGLEAAQIHKEGQIVHLHLQFKDGLEREYIYRVEEEH

Nucleotide

• Length: 438 bp

>NTDB_id=197448 WH25_RS10360 WP_046164732.1 2161728..2162165(-) (comGF/cglF) [Streptococcus gordonii strain IE35]
ATGTTGAAAAAAGGTAAAGTAGGAGCTTTTACCTTGCTGGAAGCCTTAGTAGCCCTCTTGGTCATCAGTGGTGGCCTCTT
GGTTTTTCAAGCTATGACTAAGCTTCTAGCCAGCGAAATTCAGCTTCAAGAGCAGACTAAGGCTAAGGAATGGCTCTTGT
TTGCGGACCAGCTAGATGTAGAACTATCTCGTAGCCATTTTGAAAAGGTTGAGCAAAACAAGCTTTATGTTAAACAAGAT
GGTAAGTCGATTGCCTTTGGTAAGTCTAAAAGCGATGATTTTCGAAAGACGGATGCGAATGGCCATGGTTATCAACCCAT
GATTTATGGCTTAGAAGCTGCTCAAATACATAAAGAAGGTCAGATAGTTCATTTGCATCTGCAGTTTAAGGACGGCTTAG
AAAGAGAGTACATCTATCGTGTTGAAGAAGAACATTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	67.606	97.931	0.662
comGF/cglF	Streptococcus pneumoniae D39	67.606	97.931	0.662
comGF/cglF	Streptococcus pneumoniae R6	67.606	97.931	0.662
comGF/cglF	Streptococcus pneumoniae TIGR4	67.606	97.931	0.662
comGF/cglF	Streptococcus mitis NCTC 12261	65.957	97.241	0.641
comGF/cglF	Streptococcus mitis SK321	64.539	97.241	0.628
comYF	Streptococcus mutans UA140	46.479	97.931	0.455
comYF	Streptococcus mutans UA159	45.775	97.931	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	42.857	96.552	0.414