Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   WH25_RS10380 Genome accession   NZ_CP017295
Coordinates   2163116..2164150 (-) Length   344 a.a.
NCBI ID   WP_046164735.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2158116..2169150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS10340 (WH25_10340) - 2158379..2159044 (-) 666 WP_046164730.1 CPBP family intramembrane glutamic endopeptidase -
  WH25_RS10345 (WH25_10345) - 2159092..2160282 (-) 1191 WP_045634156.1 acetate kinase -
  WH25_RS10350 (WH25_10350) comYH 2160332..2161285 (-) 954 WP_046164731.1 class I SAM-dependent methyltransferase Machinery gene
  WH25_RS10355 (WH25_10355) comGG 2161316..2161747 (-) 432 WP_231108792.1 competence type IV pilus minor pilin ComGG -
  WH25_RS10360 (WH25_10360) comGF/cglF 2161728..2162165 (-) 438 WP_046164732.1 competence type IV pilus minor pilin ComGF Machinery gene
  WH25_RS10365 (WH25_10365) comGE/cglE 2162149..2162442 (-) 294 WP_046164733.1 competence type IV pilus minor pilin ComGE Machinery gene
  WH25_RS10370 (WH25_10370) comYD 2162414..2162842 (-) 429 WP_069097080.1 competence type IV pilus minor pilin ComGD Machinery gene
  WH25_RS10375 (WH25_10375) comYC 2162802..2163119 (-) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  WH25_RS10380 (WH25_10380) comYB 2163116..2164150 (-) 1035 WP_046164735.1 competence type IV pilus assembly protein ComGB Machinery gene
  WH25_RS10385 (WH25_10385) comYA 2164083..2165021 (-) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  WH25_RS10390 (WH25_10390) - 2165123..2165491 (-) 369 WP_046164737.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39158.24 Da        Isoelectric Point: 9.1979

>NTDB_id=197452 WH25_RS10380 WP_046164735.1 2163116..2164150(-) (comYB) [Streptococcus gordonii strain IE35]
MISFLQQDISILSKQRQKKLGTSKQKQVIELFNNLFSSGFHLAETVDFLGRSALLEQNYVQQMRRGLANGQAFSEIMTSL
GFSDAVVTQLSLAELHGNLSLALLKIEEYLDNLAKVKKKLIEVATYPMMLLGFLVLIMMGLRNYLLPQLSSQNFATQLIG
HLPTIFLLTVLMLLGLTGAIYLIFKGQKRIPVYSFLARLPFVGSFVKIYLTAYYAREWGNMIGQGLELSQIFQIMQEQRS
VLFQEIGQDLGQALQNGQEFSDKIASYPFFKKELSLIIEYGEVKSKLGSELEIYALKTWEEFFGRVNRTMNLIQPLVFVF
VALMIVLLYAAMLLPLYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=197452 WH25_RS10380 WP_046164735.1 2163116..2164150(-) (comYB) [Streptococcus gordonii strain IE35]
TTGATCAGCTTCTTGCAGCAGGACATATCCATCCTGAGCAAGCAGAGGCAGAAAAAATTAGGAACTAGCAAGCAAAAGCA
GGTCATTGAACTGTTTAATAATTTATTCTCTAGCGGTTTTCATTTGGCTGAGACTGTGGATTTTTTAGGACGAAGTGCTC
TTTTGGAGCAGAACTATGTTCAGCAAATGCGTCGTGGCTTAGCTAATGGACAAGCATTTTCAGAGATTATGACTAGTCTA
GGTTTTTCTGATGCGGTAGTAACCCAGCTGTCATTGGCTGAGTTACATGGGAATTTATCGCTTGCCTTGCTAAAAATAGA
GGAATATCTGGATAATCTTGCTAAGGTAAAAAAGAAGCTAATTGAAGTAGCGACCTATCCCATGATGCTTCTCGGCTTTT
TGGTATTGATTATGATGGGATTGAGAAATTACCTATTACCCCAACTCAGCAGTCAAAATTTTGCAACTCAACTCATTGGT
CATTTGCCTACTATTTTTCTACTAACCGTCTTAATGTTACTTGGATTAACAGGAGCGATTTATCTGATTTTCAAAGGCCA
GAAACGGATCCCTGTATACTCTTTCTTAGCTCGCCTGCCTTTTGTTGGATCCTTTGTAAAGATCTACCTAACCGCCTATT
ATGCGCGTGAATGGGGCAATATGATTGGGCAAGGCTTGGAGCTCAGTCAGATTTTTCAGATTATGCAAGAGCAACGCTCG
GTTTTATTTCAGGAAATTGGTCAAGATTTAGGTCAAGCTTTACAAAACGGTCAAGAATTTTCAGATAAAATTGCTTCGTA
TCCTTTTTTCAAAAAGGAATTGTCTCTAATCATCGAATACGGGGAAGTCAAATCTAAGCTGGGAAGCGAACTAGAAATCT
ATGCTCTTAAGACTTGGGAAGAATTTTTTGGTAGGGTCAATCGGACCATGAATCTGATTCAGCCCCTAGTCTTTGTCTTT
GTAGCCTTGATGATTGTCTTACTGTATGCGGCAATGCTATTGCCCCTTTATCAAAATATGGAGGTTCATCTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(30-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

97.965

100

0.98
  comGB/cglB Streptococcus mitis NCTC 12261

71.848

99.128

0.712
  comGB/cglB Streptococcus mitis SK321

72.024

97.674

0.703
  comGB/cglB Streptococcus pneumoniae TIGR4

71.131

97.674

0.695
  comGB/cglB Streptococcus pneumoniae R6

71.131

97.674

0.695
  comGB/cglB Streptococcus pneumoniae Rx1

71.131

97.674

0.695
  comGB/cglB Streptococcus pneumoniae D39

71.131

97.674

0.695
  comYB Streptococcus mutans UA140

59.767

99.709

0.596
  comYB Streptococcus mutans UA159

59.475

99.709

0.593
  comGB Lactococcus lactis subsp. cremoris KW2

51.039

97.965

0.5

Multiple sequence alignment