Detailed information NTG0180664

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: A6M16_RS00785
• Genome accession: NZ_CP015557
• Coordinates: 123417..123698 (+)
• Length: 93 a.a.
• NCBI ID: WP_009909092.1
• Uniprot ID: A0A116MYU4
• Organism: Streptococcus suis strain DN13
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 118417..128698

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6M16_RS00765 (A6M16_00765)	-	120080..120445 (+)	366	WP_024417409.1	DUF1033 family protein	-
A6M16_RS00770 (A6M16_00770)	-	120480..121430 (-)	951	WP_024417410.1	S66 family peptidase	-
A6M16_RS00775 (A6M16_00775)	comYA	121516..122466 (+)	951	WP_024417411.1	competence type IV pilus ATPase ComGA	Machinery gene
A6M16_RS00780 (A6M16_00780)	comYB	122378..123415 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
A6M16_RS00785 (A6M16_00785)	comYC	123417..123698 (+)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
A6M16_RS00790 (A6M16_00790)	comGD	123679..124086 (+)	408	WP_024387070.1	competence type IV pilus minor pilin ComGD	-
A6M16_RS00795 (A6M16_00795)	comYE	124058..124351 (+)	294	WP_024390433.1	competence type IV pilus minor pilin ComGE	Machinery gene
A6M16_RS00800 (A6M16_00800)	comGF/cglF	124338..124772 (+)	435	WP_063725150.1	competence type IV pilus minor pilin ComGF	Machinery gene
A6M16_RS00805 (A6M16_00805)	comGG	124750..125160 (+)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
A6M16_RS00810 (A6M16_00810)	comYH	125217..126170 (+)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
A6M16_RS00815 (A6M16_00815)	-	126220..127407 (+)	1188	WP_014637319.1	acetate kinase	-
A6M16_RS00820 (A6M16_00820)	-	127722..128273 (+)	552	WP_024417413.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10320.28 Da
• Isoelectric Point: 8.4284

>NTDB_id=180664 A6M16_RS00785 WP_009909092.1 123417..123698(+) (comYC) [Streptococcus suis strain DN13]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEHDKEATVADLQAAGYI
TEKQAKQYAAAKK

Nucleotide

• Length: 282 bp

>NTDB_id=180664 A6M16_RS00785 WP_009909092.1 123417..123698(+) (comYC) [Streptococcus suis strain DN13]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCCTTTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGCCAGATGGAGCTCTATGAATTGGAACATGACAAGGAAGCAACGGTGGCAGACTTGCAGGCAGCTGGCTACATC
ACTGAAAAACAAGCAAAACAGTATGCTGCGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A116MYU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	96.774	100	0.968
comGC/cglC	Streptococcus mitis SK321	67.059	91.398	0.613
comGC/cglC	Streptococcus mitis NCTC 12261	67.059	91.398	0.613
comYC	Streptococcus gordonii str. Challis substr. CH1	62.637	97.849	0.613
comGC/cglC	Streptococcus pneumoniae R6	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae D39	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae TIGR4	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae Rx1	69.136	87.097	0.602
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	57.955	94.624	0.548
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Bacillus subtilis subsp. subtilis str. 168	49.333	80.645	0.398