Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   A6M16_RS00775 Genome accession   NZ_CP015557
Coordinates   121516..122466 (+) Length   316 a.a.
NCBI ID   WP_024417411.1    Uniprot ID   -
Organism   Streptococcus suis strain DN13     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 116516..127466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M16_RS00765 (A6M16_00765) - 120080..120445 (+) 366 WP_024417409.1 DUF1033 family protein -
  A6M16_RS00770 (A6M16_00770) - 120480..121430 (-) 951 WP_024417410.1 S66 family peptidase -
  A6M16_RS00775 (A6M16_00775) comYA 121516..122466 (+) 951 WP_024417411.1 competence type IV pilus ATPase ComGA Machinery gene
  A6M16_RS00780 (A6M16_00780) comYB 122378..123415 (+) 1038 WP_255195823.1 competence type IV pilus assembly protein ComGB Machinery gene
  A6M16_RS00785 (A6M16_00785) comYC 123417..123698 (+) 282 WP_009909092.1 competence type IV pilus major pilin ComGC Machinery gene
  A6M16_RS00790 (A6M16_00790) comGD 123679..124086 (+) 408 WP_024387070.1 competence type IV pilus minor pilin ComGD -
  A6M16_RS00795 (A6M16_00795) comYE 124058..124351 (+) 294 WP_024390433.1 competence type IV pilus minor pilin ComGE Machinery gene
  A6M16_RS00800 (A6M16_00800) comGF/cglF 124338..124772 (+) 435 WP_063725150.1 competence type IV pilus minor pilin ComGF Machinery gene
  A6M16_RS00805 (A6M16_00805) comGG 124750..125160 (+) 411 WP_009909099.1 competence type IV pilus minor pilin ComGG -
  A6M16_RS00810 (A6M16_00810) comYH 125217..126170 (+) 954 WP_024409299.1 class I SAM-dependent methyltransferase Machinery gene
  A6M16_RS00815 (A6M16_00815) - 126220..127407 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35407.25 Da        Isoelectric Point: 5.9423

>NTDB_id=180662 A6M16_RS00775 WP_024417411.1 121516..122466(+) (comYA) [Streptococcus suis strain DN13]
MIQEKSRKLIEKAVADRVSDIYLVPRGESYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=180662 A6M16_RS00775 WP_024417411.1 121516..122466(+) (comYA) [Streptococcus suis strain DN13]
ATGATTCAAGAAAAATCAAGAAAGTTGATTGAAAAGGCAGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGCGG
GGAAAGCTATCAAGTTTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTCTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ATCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACAGGAGCTACCGTTTTCTCAACGGTTCATGCAAGGTCTATTTCGGGTGTCTAT
GCTCGTATGTTGGAATTGGGTGTCAGTCCTGAGGAGTTAAACAATGCCCTTCAAGGTATTGCCTATCAACGTTTAATCGG
GGGAGGAGGTGTGGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.387

98.101

0.671
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.161

98.101

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.628

100

0.538
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364

Multiple sequence alignment