Detailed information NTG0180666

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: A6M16_RS00800
• Genome accession: NZ_CP015557
• Coordinates: 124338..124772 (+)
• Length: 144 a.a.
• NCBI ID: WP_063725150.1
• Uniprot ID: -
• Organism: Streptococcus suis strain DN13
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 119338..129772

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6M16_RS00765 (A6M16_00765)	-	120080..120445 (+)	366	WP_024417409.1	DUF1033 family protein	-
A6M16_RS00770 (A6M16_00770)	-	120480..121430 (-)	951	WP_024417410.1	S66 family peptidase	-
A6M16_RS00775 (A6M16_00775)	comYA	121516..122466 (+)	951	WP_024417411.1	competence type IV pilus ATPase ComGA	Machinery gene
A6M16_RS00780 (A6M16_00780)	comYB	122378..123415 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
A6M16_RS00785 (A6M16_00785)	comYC	123417..123698 (+)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
A6M16_RS00790 (A6M16_00790)	comGD	123679..124086 (+)	408	WP_024387070.1	competence type IV pilus minor pilin ComGD	-
A6M16_RS00795 (A6M16_00795)	comYE	124058..124351 (+)	294	WP_024390433.1	competence type IV pilus minor pilin ComGE	Machinery gene
A6M16_RS00800 (A6M16_00800)	comGF/cglF	124338..124772 (+)	435	WP_063725150.1	competence type IV pilus minor pilin ComGF	Machinery gene
A6M16_RS00805 (A6M16_00805)	comGG	124750..125160 (+)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
A6M16_RS00810 (A6M16_00810)	comYH	125217..126170 (+)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
A6M16_RS00815 (A6M16_00815)	-	126220..127407 (+)	1188	WP_014637319.1	acetate kinase	-
A6M16_RS00820 (A6M16_00820)	-	127722..128273 (+)	552	WP_024417413.1	folate family ECF transporter S component	-
A6M16_RS00825 (A6M16_00825)	-	128329..129585 (+)	1257	WP_024417414.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16420.77 Da
• Isoelectric Point: 6.9834

>NTDB_id=180666 A6M16_RS00800 WP_063725150.1 124338..124772(+) (comGF/cglF) [Streptococcus suis strain DN13]
MLKSKIPAFTLLECLVALVILSGSLLVFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVDKDG
QALAFGKSRSDDFRKTNDRGQGYQPMLYQVDSAAISQEKQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=180666 A6M16_RS00800 WP_063725150.1 124338..124772(+) (comGF/cglF) [Streptococcus suis strain DN13]
TTGTTAAAAAGTAAAATTCCTGCTTTTACTCTCTTGGAATGCTTGGTAGCCTTAGTCATCCTTTCAGGTAGTCTTCTGGT
CTTTGAAGGCTTGTCAAAACTGCTGGTCCAAGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGCCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCGATAAGGATGGA
CAAGCATTAGCCTTTGGCAAGTCACGGTCGGATGATTTTCGGAAAACAAATGACAGGGGACAGGGTTACCAGCCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTCCCAAGAAAAGCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GGACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae TIGR4	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae Rx1	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae D39	53.901	97.917	0.528
comGF/cglF	Streptococcus pneumoniae R6	53.901	97.917	0.528
comGF/cglF	Streptococcus mitis NCTC 12261	54.478	93.056	0.507
comYF	Streptococcus mutans UA140	50	100	0.5
comYF	Streptococcus mutans UA159	49.306	100	0.493
comGF/cglF	Streptococcus mitis SK321	51.493	93.056	0.479
comGF	Lactococcus lactis subsp. cremoris KW2	47.518	97.917	0.465