Detailed information
Bioinformatically predicted
Overview
| Name | comE/blpR | Type | Regulator |
| Locus tag | APQ13_RS08940 | Genome accession | NZ_CP013237 |
| Coordinates | 1846141..1846893 (+) | Length | 250 a.a. |
| NCBI ID | WP_002262114.1 | Uniprot ID | Q8DS93 |
| Organism | Streptococcus mutans strain NG8 isolate Dental Plaque | ||
| Function | activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation |
||
Genomic Context
Location: 1841141..1851893
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| APQ13_RS08920 (APQ13_08900) | dnaI | 1842060..1842959 (+) | 900 | WP_002267936.1 | primosomal protein DnaI | - |
| APQ13_RS08925 (APQ13_08905) | der | 1842972..1844282 (+) | 1311 | WP_002266899.1 | ribosome biogenesis GTPase Der | - |
| APQ13_RS08930 (APQ13_08910) | - | 1844357..1844983 (+) | 627 | WP_002266898.1 | hypothetical protein | - |
| APQ13_RS08935 (APQ13_08915) | - | 1845031..1845669 (+) | 639 | WP_002262115.1 | VTT domain-containing protein | - |
| APQ13_RS08940 (APQ13_08920) | comE/blpR | 1846141..1846893 (+) | 753 | WP_002262114.1 | response regulator transcription factor | Regulator |
| APQ13_RS08945 (APQ13_08925) | comD/blpH | 1846890..1848215 (+) | 1326 | WP_002289696.1 | sensor histidine kinase | Regulator |
| APQ13_RS08950 (APQ13_08930) | comC/blpC | 1848357..1848497 (-) | 141 | WP_002267610.1 | ComC/BlpC family leader-containing pheromone/bacteriocin | Regulator |
| APQ13_RS08955 (APQ13_08935) | cipB | 1848764..1848994 (+) | 231 | WP_002265368.1 | Blp family class II bacteriocin | Regulator |
| APQ13_RS08960 (APQ13_08940) | - | 1849125..1849526 (+) | 402 | WP_002310604.1 | hypothetical protein | - |
| APQ13_RS08965 (APQ13_08945) | - | 1850900..1851319 (+) | 420 | WP_002263913.1 | hypothetical protein | - |
| APQ13_RS08970 (APQ13_08950) | - | 1851466..1851870 (+) | 405 | WP_002263912.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 250 a.a. Molecular weight: 29358.71 Da Isoelectric Point: 8.2551
>NTDB_id=161018 APQ13_RS08940 WP_002262114.1 1846141..1846893(+) (comE/blpR) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MISIFVLEDDFLQQGRLETTIAAIMKEKNWSYKELTIFGKPQQLIDAIPEKGNHQIFFLDIEIKKEEKKGLEVANQIRQH
NPSAVIVFVTTHSEFMPLTFQYQVSALDFIDKSLNPEEFSHRIESALYYAMENSQKNGQSEELFIFHSSETQFQVPFAEI
LYFETSSTAHKLCLYTYDERIEFYGSMTDIVKMDKRLFQCHRSFIVNPANITRIDRKKRLAYFRNNKSCLISRTKLTKLR
AVIADQRRAK
MISIFVLEDDFLQQGRLETTIAAIMKEKNWSYKELTIFGKPQQLIDAIPEKGNHQIFFLDIEIKKEEKKGLEVANQIRQH
NPSAVIVFVTTHSEFMPLTFQYQVSALDFIDKSLNPEEFSHRIESALYYAMENSQKNGQSEELFIFHSSETQFQVPFAEI
LYFETSSTAHKLCLYTYDERIEFYGSMTDIVKMDKRLFQCHRSFIVNPANITRIDRKKRLAYFRNNKSCLISRTKLTKLR
AVIADQRRAK
Nucleotide
Download Length: 753 bp
>NTDB_id=161018 APQ13_RS08940 WP_002262114.1 1846141..1846893(+) (comE/blpR) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGATTTCTATTTTTGTATTGGAAGATGATTTTTTACAACAAGGACGTCTTGAAACCACCATTGCAGCTATCATGAAAGA
AAAAAATTGGTCTTATAAAGAATTGACTATTTTTGGAAAACCACAACAACTTATTGACGCTATCCCTGAAAAGGGCAATC
ACCAGATTTTCTTTTTGGATATTGAAATCAAAAAAGAGGAAAAGAAAGGACTGGAAGTAGCCAATCAGATTAGACAGCAT
AATCCTAGTGCAGTTATTGTCTTTGTCACGACACATTCTGAGTTTATGCCCCTCACTTTTCAGTATCAGGTATCTGCTTT
GGATTTTATTGATAAATCTTTGAATCCTGAGGAGTTCTCCCACCGCATTGAATCAGCGCTGTATTATGCTATGGAAAACA
GCCAGAAGAATGGTCAATCAGAGGAACTTTTTATTTTCCATTCATCTGAAACTCAGTTTCAGGTCCCTTTTGCTGAGATT
CTGTATTTTGAAACATCTTCAACAGCCCATAAGCTCTGCCTTTATACTTATGATGAACGGATTGAATTCTACGGCAGTAT
GACTGACATTGTTAAAATGGATAAGAGACTTTTTCAGTGCCATCGCTCTTTTATTGTCAATCCTGCCAATATTACCCGTA
TTGATCGGAAAAAACGCTTGGCCTATTTTCGAAATAATAAGTCTTGTCTTATTTCACGAACTAAGTTAACAAAACTGAGA
GCTGTGATTGCTGATCAAAGGAGAGCAAAATGA
ATGATTTCTATTTTTGTATTGGAAGATGATTTTTTACAACAAGGACGTCTTGAAACCACCATTGCAGCTATCATGAAAGA
AAAAAATTGGTCTTATAAAGAATTGACTATTTTTGGAAAACCACAACAACTTATTGACGCTATCCCTGAAAAGGGCAATC
ACCAGATTTTCTTTTTGGATATTGAAATCAAAAAAGAGGAAAAGAAAGGACTGGAAGTAGCCAATCAGATTAGACAGCAT
AATCCTAGTGCAGTTATTGTCTTTGTCACGACACATTCTGAGTTTATGCCCCTCACTTTTCAGTATCAGGTATCTGCTTT
GGATTTTATTGATAAATCTTTGAATCCTGAGGAGTTCTCCCACCGCATTGAATCAGCGCTGTATTATGCTATGGAAAACA
GCCAGAAGAATGGTCAATCAGAGGAACTTTTTATTTTCCATTCATCTGAAACTCAGTTTCAGGTCCCTTTTGCTGAGATT
CTGTATTTTGAAACATCTTCAACAGCCCATAAGCTCTGCCTTTATACTTATGATGAACGGATTGAATTCTACGGCAGTAT
GACTGACATTGTTAAAATGGATAAGAGACTTTTTCAGTGCCATCGCTCTTTTATTGTCAATCCTGCCAATATTACCCGTA
TTGATCGGAAAAAACGCTTGGCCTATTTTCGAAATAATAAGTCTTGTCTTATTTCACGAACTAAGTTAACAAAACTGAGA
GCTGTGATTGCTGATCAAAGGAGAGCAAAATGA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comE/blpR | Streptococcus mutans UA159 |
100 |
100 |
1 |
| comE/comE1 | Streptococcus equinus JB1 |
46.888 |
96.4 |
0.452 |
| comE | Streptococcus mitis NCTC 12261 |
41.7 |
98.8 |
0.412 |
| comE | Streptococcus infantis strain Atu-4 |
41.7 |
98.8 |
0.412 |
| comE | Streptococcus pneumoniae D39 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus pneumoniae Rx1 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus pneumoniae R6 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus pneumoniae TIGR4 |
41.296 |
98.8 |
0.408 |
| comE | Streptococcus mitis SK321 |
41.296 |
98.8 |
0.408 |
| comE/comE2 | Streptococcus equinus JB1 |
40.664 |
96.4 |
0.392 |
| comE/comE1 | Streptococcus gordonii str. Challis substr. CH1 |
37.551 |
98 |
0.368 |
| comE/comE2 | Streptococcus gordonii strain NCTC7865 |
37.551 |
98 |
0.368 |