Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/blpC   Type   Regulator
Locus tag   APQ13_RS08950 Genome accession   NZ_CP013237
Coordinates   1848357..1848497 (-) Length   46 a.a.
NCBI ID   WP_002267610.1    Uniprot ID   Q99QI5
Organism   Streptococcus mutans strain NG8 isolate Dental Plaque     
Function   binding to ComD; induce autophosphorylation of ComD; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context


Location: 1843357..1853497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ13_RS08930 (APQ13_08910) - 1844357..1844983 (+) 627 WP_002266898.1 hypothetical protein -
  APQ13_RS08935 (APQ13_08915) - 1845031..1845669 (+) 639 WP_002262115.1 VTT domain-containing protein -
  APQ13_RS08940 (APQ13_08920) comE/blpR 1846141..1846893 (+) 753 WP_002262114.1 response regulator transcription factor Regulator
  APQ13_RS08945 (APQ13_08925) comD/blpH 1846890..1848215 (+) 1326 WP_002289696.1 sensor histidine kinase Regulator
  APQ13_RS08950 (APQ13_08930) comC/blpC 1848357..1848497 (-) 141 WP_002267610.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  APQ13_RS08955 (APQ13_08935) cipB 1848764..1848994 (+) 231 WP_002265368.1 Blp family class II bacteriocin Regulator
  APQ13_RS08960 (APQ13_08940) - 1849125..1849526 (+) 402 WP_002310604.1 hypothetical protein -
  APQ13_RS08965 (APQ13_08945) - 1850900..1851319 (+) 420 WP_002263913.1 hypothetical protein -
  APQ13_RS08970 (APQ13_08950) - 1851466..1851870 (+) 405 WP_002263912.1 hypothetical protein -
  APQ13_RS10430 - 1851993..1852205 (-) 213 Protein_1746 IS3 family transposase -
  APQ13_RS10095 - 1852645..1852809 (+) 165 WP_002265308.1 hypothetical protein -
  APQ13_RS08980 (APQ13_08960) - 1853214..1853426 (+) 213 WP_002263744.1 Blp family class II bacteriocin -

Sequence


Protein


Download         Length: 46 a.a.        Molecular weight: 5211.06 Da        Isoelectric Point: 10.4929

>NTDB_id=161020 APQ13_RS08950 WP_002267610.1 1848357..1848497(-) (comC/blpC) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MKKTLSLKNDFKEIKTDELEIIIGGSGSLSTFFRLFNRSFTQALGK

Nucleotide


Download         Length: 141 bp        

>NTDB_id=161020 APQ13_RS08950 WP_002267610.1 1848357..1848497(-) (comC/blpC) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGAAAAAAACACTATCATTAAAAAATGACTTTAAAGAAATTAAGACTGATGAATTAGAGATTATCATTGGCGGAAGCGG
AAGCCTATCAACATTTTTCCGGCTGTTTAACAGAAGTTTTACACAAGCTTTGGGAAAATAA

Domains


Predicted by InterproScan.

(1-32)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  PDB 2I2J

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/blpC Streptococcus mutans UA159

100

100

1


Multiple sequence alignment