Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   APQ13_RS08945 Genome accession   NZ_CP013237
Coordinates   1846890..1848215 (+) Length   441 a.a.
NCBI ID   WP_002289696.1    Uniprot ID   -
Organism   Streptococcus mutans strain NG8 isolate Dental Plaque     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1841890..1853215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APQ13_RS08920 (APQ13_08900) dnaI 1842060..1842959 (+) 900 WP_002267936.1 primosomal protein DnaI -
  APQ13_RS08925 (APQ13_08905) der 1842972..1844282 (+) 1311 WP_002266899.1 ribosome biogenesis GTPase Der -
  APQ13_RS08930 (APQ13_08910) - 1844357..1844983 (+) 627 WP_002266898.1 hypothetical protein -
  APQ13_RS08935 (APQ13_08915) - 1845031..1845669 (+) 639 WP_002262115.1 VTT domain-containing protein -
  APQ13_RS08940 (APQ13_08920) comE/blpR 1846141..1846893 (+) 753 WP_002262114.1 response regulator transcription factor Regulator
  APQ13_RS08945 (APQ13_08925) comD/blpH 1846890..1848215 (+) 1326 WP_002289696.1 sensor histidine kinase Regulator
  APQ13_RS08950 (APQ13_08930) comC/blpC 1848357..1848497 (-) 141 WP_002267610.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  APQ13_RS08955 (APQ13_08935) cipB 1848764..1848994 (+) 231 WP_002265368.1 Blp family class II bacteriocin Regulator
  APQ13_RS08960 (APQ13_08940) - 1849125..1849526 (+) 402 WP_002310604.1 hypothetical protein -
  APQ13_RS08965 (APQ13_08945) - 1850900..1851319 (+) 420 WP_002263913.1 hypothetical protein -
  APQ13_RS08970 (APQ13_08950) - 1851466..1851870 (+) 405 WP_002263912.1 hypothetical protein -
  APQ13_RS10430 - 1851993..1852205 (-) 213 Protein_1746 IS3 family transposase -
  APQ13_RS10095 - 1852645..1852809 (+) 165 WP_002265308.1 hypothetical protein -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50574.71 Da        Isoelectric Point: 9.8211

>NTDB_id=161019 APQ13_RS08945 WP_002289696.1 1846890..1848215(+) (comD/blpH) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIALSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGTQGIVMGSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQVLYVIESYNVIPTLKFRKFVVIVYLILFLILFSFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSSKIQLPEMELLDFITILSILCDNAIEAAFESLNPEIQLAFFKKNGSIVFIIQNSTKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSNHHHLFKQLLIIK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=161019 APQ13_RS08945 WP_002289696.1 1846890..1848215(+) (comD/blpH) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTGAACGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGCTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAACTCAAGGAATTGTAATGGGCAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTCAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATTCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGTATTGTATGTTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGTTCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTGTCAGCAAAAATCTTAGAAGCTCAGAATAAA
AAGATTGCTGTCAATGTAGAAGTCTCAAGTAAAATACAACTGCCTGAGATGGAGTTGCTTGATTTCATTACCATACTTTC
TATCTTGTGTGATAATGCCATTGAGGCTGCTTTCGAATCATTAAATCCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGTATAGTCTTTATCATTCAGAATTCCACCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAATCATCATCATTTATTCAAGCAACTCCTAATAATAAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

99.773

100

0.998

Multiple sequence alignment