Detailed information    

insolico Bioinformatically predicted

Overview

Name   ssbA   Type   Machinery gene
Locus tag   SpyM6JRS4_RS06270 Genome accession   NZ_CP011414
Coordinates   1252134..1252553 (-) Length   139 a.a.
NCBI ID   WP_011018140.1    Uniprot ID   -
Organism   Streptococcus pyogenes JRS4     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1220560..1262054 1252134..1252553 within 0


Gene organization within MGE regions


Location: 1220560..1262054
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SpyM6JRS4_RS06045 (SpyM6JRS4_06040) prx 1220560..1220742 (-) 183 WP_011018104.1 hypothetical protein Regulator
  SpyM6JRS4_RS06050 (SpyM6JRS4_06045) sda 1220982..1221980 (+) 999 WP_032463908.1 streptodornase A -
  SpyM6JRS4_RS06055 (SpyM6JRS4_06050) - 1222121..1222714 (-) 594 WP_003051628.1 GNAT family N-acetyltransferase -
  SpyM6JRS4_RS06060 (SpyM6JRS4_06055) - 1222714..1222878 (-) 165 WP_021340366.1 hypothetical protein -
  SpyM6JRS4_RS06065 (SpyM6JRS4_06060) - 1223027..1224232 (-) 1206 WP_023078214.1 glucosaminidase domain-containing protein -
  SpyM6JRS4_RS06075 (SpyM6JRS4_06070) - 1224345..1224530 (-) 186 WP_011184796.1 holin -
  SpyM6JRS4_RS06080 (SpyM6JRS4_06075) - 1224527..1224826 (-) 300 WP_011184797.1 hypothetical protein -
  SpyM6JRS4_RS06085 (SpyM6JRS4_06080) - 1224837..1225454 (-) 618 WP_011018111.1 DUF1366 domain-containing protein -
  SpyM6JRS4_RS06090 (SpyM6JRS4_06085) - 1225457..1225885 (-) 429 WP_011184798.1 DUF1617 family protein -
  SpyM6JRS4_RS06095 (SpyM6JRS4_06090) - 1225897..1227912 (-) 2016 WP_011184799.1 gp58-like family protein -
  SpyM6JRS4_RS06100 (SpyM6JRS4_06095) - 1227927..1229039 (-) 1113 WP_011184800.1 hyaluronoglucosaminidase -
  SpyM6JRS4_RS06105 (SpyM6JRS4_06100) - 1229039..1231186 (-) 2148 WP_023078210.1 phage tail spike protein -
  SpyM6JRS4_RS06110 (SpyM6JRS4_06105) - 1231183..1231899 (-) 717 WP_011018116.1 distal tail protein Dit -
  SpyM6JRS4_RS06115 (SpyM6JRS4_06110) - 1231896..1235156 (-) 3261 WP_047149499.1 tape measure protein -
  SpyM6JRS4_RS06120 (SpyM6JRS4_06115) - 1235146..1235727 (-) 582 WP_011018118.1 Gp15 family bacteriophage protein -
  SpyM6JRS4_RS06125 (SpyM6JRS4_06120) - 1235731..1236165 (-) 435 WP_011018119.1 hypothetical protein -
  SpyM6JRS4_RS06130 (SpyM6JRS4_06125) - 1236209..1236670 (-) 462 WP_011018120.1 phage tail tube protein -
  SpyM6JRS4_RS06135 (SpyM6JRS4_06130) - 1236670..1237068 (-) 399 WP_011018121.1 minor capsid protein -
  SpyM6JRS4_RS06140 (SpyM6JRS4_06135) - 1237065..1237421 (-) 357 WP_010922083.1 minor capsid protein -
  SpyM6JRS4_RS06145 (SpyM6JRS4_06140) - 1237421..1237753 (-) 333 WP_010922082.1 minor capsid protein -
  SpyM6JRS4_RS06150 (SpyM6JRS4_06145) - 1237743..1238159 (-) 417 WP_011018123.1 hypothetical protein -
  SpyM6JRS4_RS06155 (SpyM6JRS4_06150) - 1238213..1239031 (-) 819 WP_010922080.1 N4-gp56 family major capsid protein -
  SpyM6JRS4_RS06160 (SpyM6JRS4_06155) - 1239035..1239649 (-) 615 WP_010922079.1 hypothetical protein -
  SpyM6JRS4_RS06165 (SpyM6JRS4_06160) - 1239775..1240041 (-) 267 WP_010922078.1 hypothetical protein -
  SpyM6JRS4_RS06170 (SpyM6JRS4_06165) - 1240128..1240355 (-) 228 WP_010922077.1 hypothetical protein -
  SpyM6JRS4_RS06175 (SpyM6JRS4_06170) - 1240355..1241848 (-) 1494 WP_011018124.1 phage minor capsid protein -
  SpyM6JRS4_RS06180 (SpyM6JRS4_06175) - 1241853..1243354 (-) 1502 Protein_1192 phage portal protein -
  SpyM6JRS4_RS06185 (SpyM6JRS4_06180) - 1243368..1244659 (-) 1292 Protein_1193 PBSX family phage terminase large subunit -
  SpyM6JRS4_RS06190 (SpyM6JRS4_06185) - 1244662..1245135 (-) 474 WP_011018127.1 hypothetical protein -
  SpyM6JRS4_RS06195 (SpyM6JRS4_06190) - 1245186..1245563 (-) 378 WP_002986841.1 ASCH domain-containing protein -
  SpyM6JRS4_RS09260 (SpyM6JRS4_06195) - 1245624..1246100 (-) 477 WP_174148345.1 GNAT family N-acetyltransferase -
  SpyM6JRS4_RS06205 (SpyM6JRS4_06200) - 1246016..1246693 (-) 678 WP_011018129.1 ABC transporter ATP-binding protein -
  SpyM6JRS4_RS06210 (SpyM6JRS4_06205) - 1246672..1247190 (-) 519 WP_011018130.1 ParB N-terminal domain-containing protein -
  SpyM6JRS4_RS06215 (SpyM6JRS4_06210) - 1247654..1248094 (-) 441 WP_002990052.1 ArpU family phage packaging/lysis transcriptional regulator -
  SpyM6JRS4_RS06220 (SpyM6JRS4_06215) - 1248368..1248634 (-) 267 WP_011018131.1 hypothetical protein -
  SpyM6JRS4_RS06225 (SpyM6JRS4_06220) - 1248631..1249002 (-) 372 WP_011018132.1 DUF1642 domain-containing protein -
  SpyM6JRS4_RS06230 (SpyM6JRS4_06225) - 1249123..1249755 (-) 633 WP_011018133.1 N-6 DNA methylase -
  SpyM6JRS4_RS06235 (SpyM6JRS4_06230) - 1249757..1250041 (-) 285 WP_011018134.1 hypothetical protein -
  SpyM6JRS4_RS09655 - 1250038..1250208 (-) 171 WP_011018135.1 hypothetical protein -
  SpyM6JRS4_RS06240 (SpyM6JRS4_06235) - 1250205..1250609 (-) 405 WP_011018136.1 YopX family protein -
  SpyM6JRS4_RS06245 (SpyM6JRS4_06240) - 1250606..1250890 (-) 285 Protein_1206 DUF3310 domain-containing protein -
  SpyM6JRS4_RS09895 (SpyM6JRS4_06245) - 1250884..1251135 (-) 252 WP_011106665.1 hypothetical protein -
  SpyM6JRS4_RS06255 (SpyM6JRS4_06250) - 1251132..1251488 (-) 357 WP_011018138.1 hypothetical protein -
  SpyM6JRS4_RS06260 (SpyM6JRS4_06255) - 1251485..1251925 (-) 441 WP_011018139.1 RusA family crossover junction endodeoxyribonuclease -
  SpyM6JRS4_RS06265 (SpyM6JRS4_06260) - 1251925..1252128 (-) 204 WP_011106686.1 hypothetical protein -
  SpyM6JRS4_RS06270 (SpyM6JRS4_06265) ssbA 1252134..1252553 (-) 420 WP_011018140.1 single-stranded DNA-binding protein Machinery gene
  SpyM6JRS4_RS06275 (SpyM6JRS4_06270) - 1252546..1253220 (-) 675 WP_011018141.1 ERF family protein -
  SpyM6JRS4_RS06280 (SpyM6JRS4_06275) - 1253221..1253703 (-) 483 WP_011018142.1 siphovirus Gp157 family protein -
  SpyM6JRS4_RS06285 (SpyM6JRS4_06280) - 1253725..1253979 (-) 255 WP_011018143.1 hypothetical protein -
  SpyM6JRS4_RS06290 (SpyM6JRS4_06285) - 1253960..1254316 (-) 357 WP_011018144.1 HTH domain-containing protein -
  SpyM6JRS4_RS09660 - 1254327..1254464 (-) 138 WP_011018145.1 hypothetical protein -
  SpyM6JRS4_RS06295 (SpyM6JRS4_06290) - 1254464..1255306 (-) 843 WP_011018146.1 ATP-binding protein -
  SpyM6JRS4_RS06300 (SpyM6JRS4_06295) - 1255316..1256236 (-) 921 WP_021340238.1 phage replisome organizer N-terminal domain-containing protein -
  SpyM6JRS4_RS06305 (SpyM6JRS4_06300) - 1256250..1256564 (-) 315 WP_021340228.1 helix-turn-helix domain-containing protein -
  SpyM6JRS4_RS09840 - 1256580..1256714 (-) 135 WP_021340229.1 hypothetical protein -
  SpyM6JRS4_RS06310 (SpyM6JRS4_06305) - 1256745..1256996 (-) 252 WP_021340237.1 AlpA family transcriptional regulator -
  SpyM6JRS4_RS09665 - 1257235..1257402 (-) 168 WP_021340232.1 hypothetical protein -
  SpyM6JRS4_RS06320 (SpyM6JRS4_06315) - 1257406..1258125 (-) 720 WP_011018149.1 phage antirepressor KilAC domain-containing protein -
  SpyM6JRS4_RS06325 (SpyM6JRS4_06320) - 1258153..1258365 (-) 213 WP_023078130.1 hypothetical protein -
  SpyM6JRS4_RS06330 (SpyM6JRS4_06325) - 1258563..1258904 (+) 342 WP_011888679.1 helix-turn-helix transcriptional regulator -
  SpyM6JRS4_RS06335 (SpyM6JRS4_06330) - 1258888..1259274 (+) 387 WP_032463929.1 ImmA/IrrE family metallo-endopeptidase -
  SpyM6JRS4_RS06340 (SpyM6JRS4_06335) - 1259289..1260710 (+) 1422 WP_011018151.1 DUF4041 domain-containing protein -
  SpyM6JRS4_RS06345 (SpyM6JRS4_06340) - 1260888..1262054 (+) 1167 WP_011018152.1 site-specific integrase -

Sequence

Protein


Download         Length: 139 a.a.        Molecular weight: 15663.32 Da        Isoelectric Point: 4.8660

>NTDB_id=145760 SpyM6JRS4_RS06270 WP_011018140.1 1252134..1252553(-) (ssbA) [Streptococcus pyogenes JRS4]
MINNVVLVGRMTKDAELRYTASQVAVATFTLAVNRRFKEQNGEREADFINCVIWRQSAENLANWAKKGALIGITGRIQTR
NYENQQGQRVYVTEVVADNFQMLESRNQQSGQGNSSQNDNSQPFGNSNPMDISDDDLPF

Nucleotide


Download         Length: 420 bp        

>NTDB_id=145760 SpyM6JRS4_RS06270 WP_011018140.1 1252134..1252553(-) (ssbA) [Streptococcus pyogenes JRS4]
ATGATTAATAACGTAGTACTAGTTGGTCGCATGACCAAGGACGCAGAGCTTCGCTATACAGCGAGTCAAGTAGCTGTAGC
TACGTTCACACTTGCGGTAAACCGCAGATTTAAAGAGCAAAACGGGGAGAGAGAAGCAGATTTCATTAACTGTGTTATCT
GGCGACAGTCTGCTGAAAATTTAGCCAACTGGGCTAAAAAAGGTGCCTTGATCGGAATTACAGGTCGTATTCAGACACGT
AACTACGAAAACCAACAAGGACAACGTGTCTATGTAACAGAAGTTGTTGCAGATAATTTCCAAATGTTGGAAAGTCGTAA
TCAACAATCTGGTCAAGGTAACTCTTCGCAAAACGATAACAGTCAACCGTTTGGCAATTCAAACCCAATGGATATTTCAG
ACGATGATCTGCCGTTTTAA

Domains

Predicted by InterproScan.

Single-strand binding protein family (SSB)

(2-103)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

54.286

100

0.683
  ssb Latilactobacillus sakei subsp. sakei 23K

55.294

100

0.676
  ssbB/cilA Streptococcus pneumoniae TIGR4

45.324

100

0.453
  ssbB/cilA Streptococcus pneumoniae Rx1

44.604

100

0.446
  ssbB Streptococcus sobrinus strain NIDR 6715-7

44.604

100

0.446
  ssbB/cilA Streptococcus mitis NCTC 12261

44.604

100

0.446
  ssbB/cilA Streptococcus pneumoniae D39

44.604

100

0.446
  ssbB/cilA Streptococcus pneumoniae R6

44.604

100

0.446
  ssbB/cilA Streptococcus mitis SK321

44.604

100

0.446
  ssbB Bacillus subtilis subsp. subtilis str. 168

54.054

79.856

0.432
  ssbA Streptococcus mutans UA159

41.727

100

0.417
  ssb Vibrio cholerae strain A1552

31.792

100

0.396

Multiple sequence alignment