Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   ACI6O7_RS11385 Genome accession   NZ_OY725152
Coordinates   2274852..2275790 (-) Length   312 a.a.
NCBI ID   WP_143459428.1    Uniprot ID   A0A552Z125
Organism   Lactococcus lactis strain IMDO WA12L8     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2269852..2280790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI6O7_RS11345 (LLWA12L8_FAMOGCFE_02274) - 2270739..2271581 (-) 843 WP_278218023.1 metal ABC transporter substrate-binding protein -
  ACI6O7_RS11350 (LLWA12L8_FAMOGCFE_02275) - 2271578..2272015 (-) 438 WP_201248645.1 zinc-dependent MarR family transcriptional regulator -
  ACI6O7_RS11355 (LLWA12L8_FAMOGCFE_02276) comGG 2272097..2272381 (-) 285 WP_404378643.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACI6O7_RS11360 (LLWA12L8_FAMOGCFE_02277) comGF 2272420..2272866 (-) 447 WP_029344525.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACI6O7_RS11365 (LLWA12L8_FAMOGCFE_02278) comGE 2272829..2273125 (-) 297 WP_010906316.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACI6O7_RS11370 (LLWA12L8_FAMOGCFE_02279) comGD 2273097..2273528 (-) 432 WP_341275869.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACI6O7_RS11375 (LLWA12L8_FAMOGCFE_02280) comGC 2273488..2273757 (-) 270 WP_023349160.1 competence type IV pilus major pilin ComGC Machinery gene
  ACI6O7_RS11380 (LLWA12L8_FAMOGCFE_02281) comGB 2273885..2274958 (-) 1074 WP_010906319.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACI6O7_RS11385 (LLWA12L8_FAMOGCFE_02282) comGA 2274852..2275790 (-) 939 WP_143459428.1 competence type IV pilus ATPase ComGA Machinery gene

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35705.01 Da        Isoelectric Point: 6.6176

>NTDB_id=1160560 ACI6O7_RS11385 WP_143459428.1 2274852..2275790(-) (comGA) [Lactococcus lactis strain IMDO WA12L8]
MIPKMAKELIQRAIDRDASDIYLIASKEKYKLYFRQMTARVLVEEIGLEVGLALLTHFKFLAGMNTGERRRVQLGACWYE
LEESNAKRLRLSTVGDFEGNESLVIRLLHDQNKKLDFWFDEELENYDCKRGLHLFAGPVGSGKTSLMFDLARRHFTDLQV
ITIEEPVELIDSDFIQLQVNEVIGNSYDELIKLSLRHRPDLLIVGEIRDKLTAQAVLRASLTGYTVFSTVHASSIRGVIQ
RLSELGLSHWEIKNALSSVVYQRLIAGKGVLDIAKNEFESWSSENWNKKIDQLLTNGYLTPTEAKREKIKTD

Nucleotide


Download         Length: 939 bp        

>NTDB_id=1160560 ACI6O7_RS11385 WP_143459428.1 2274852..2275790(-) (comGA) [Lactococcus lactis strain IMDO WA12L8]
ATGATACCAAAAATGGCAAAAGAATTAATTCAAAGAGCAATTGATAGAGATGCATCAGATATTTATCTGATTGCTTCAAA
AGAAAAGTATAAACTTTATTTTCGACAAATGACAGCGCGTGTTCTGGTAGAAGAAATTGGGTTAGAAGTTGGCTTAGCAC
TACTTACTCACTTTAAGTTTCTAGCTGGGATGAATACAGGAGAACGCAGACGAGTTCAATTGGGAGCTTGTTGGTATGAA
TTAGAGGAAAGTAATGCAAAACGTTTGCGTCTTTCGACAGTGGGGGATTTCGAGGGTAATGAATCTTTAGTAATACGTCT
CTTGCATGATCAAAACAAAAAACTTGATTTTTGGTTTGATGAAGAGCTAGAGAATTATGATTGTAAAAGAGGATTGCATC
TCTTTGCCGGTCCAGTAGGCTCGGGCAAAACATCTTTAATGTTTGATTTAGCTCGTCGTCATTTTACAGATTTACAAGTT
ATCACTATTGAAGAACCCGTTGAGTTGATTGATTCCGATTTTATTCAGTTACAAGTCAACGAAGTCATTGGTAATAGTTA
TGATGAATTAATTAAATTATCACTGAGGCATCGCCCAGATTTGTTAATCGTTGGTGAAATTCGTGATAAATTGACCGCTC
AAGCAGTTTTACGGGCTAGTTTGACAGGTTATACAGTGTTTTCAACCGTTCATGCCTCTTCTATTAGAGGTGTCATTCAG
AGATTATCAGAGCTGGGTTTAAGTCATTGGGAAATAAAAAATGCTTTATCAAGTGTTGTTTATCAGCGTTTAATAGCTGG
GAAAGGAGTATTAGACATTGCCAAAAACGAATTTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTAC
TTACAAATGGATATCTCACACCTACTGAAGCCAAAAGGGAAAAAATTAAGACTGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A552Z125

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Lactococcus lactis subsp. cremoris KW2

76.603

100

0.766
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

54.984

99.679

0.548
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

53.698

99.679

0.535
  comYA Streptococcus mutans UA140

52.564

100

0.526
  comYA Streptococcus mutans UA159

52.564

100

0.526
  comGA/cglA/cilD Streptococcus pneumoniae R6

52.733

99.679

0.526
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

52.733

99.679

0.526
  comGA/cglA/cilD Streptococcus pneumoniae D39

52.733

99.679

0.526
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

52.733

99.679

0.526
  comYA Streptococcus gordonii str. Challis substr. CH1

51.757

100

0.519

Multiple sequence alignment