Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   ACI6O7_RS11380 Genome accession   NZ_OY725152
Coordinates   2273885..2274958 (-) Length   357 a.a.
NCBI ID   WP_010906319.1    Uniprot ID   A0A552YT77
Organism   Lactococcus lactis strain IMDO WA12L8     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2268885..2279958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI6O7_RS11335 (LLWA12L8_FAMOGCFE_02272) - 2269023..2269832 (-) 810 WP_014570791.1 metal ABC transporter permease -
  ACI6O7_RS11340 (LLWA12L8_FAMOGCFE_02273) - 2269825..2270562 (-) 738 WP_012898617.1 metal ABC transporter ATP-binding protein -
  ACI6O7_RS11345 (LLWA12L8_FAMOGCFE_02274) - 2270739..2271581 (-) 843 WP_278218023.1 metal ABC transporter substrate-binding protein -
  ACI6O7_RS11350 (LLWA12L8_FAMOGCFE_02275) - 2271578..2272015 (-) 438 WP_201248645.1 zinc-dependent MarR family transcriptional regulator -
  ACI6O7_RS11355 (LLWA12L8_FAMOGCFE_02276) comGG 2272097..2272381 (-) 285 WP_404378643.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACI6O7_RS11360 (LLWA12L8_FAMOGCFE_02277) comGF 2272420..2272866 (-) 447 WP_029344525.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACI6O7_RS11365 (LLWA12L8_FAMOGCFE_02278) comGE 2272829..2273125 (-) 297 WP_010906316.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACI6O7_RS11370 (LLWA12L8_FAMOGCFE_02279) comGD 2273097..2273528 (-) 432 WP_341275869.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACI6O7_RS11375 (LLWA12L8_FAMOGCFE_02280) comGC 2273488..2273757 (-) 270 WP_023349160.1 competence type IV pilus major pilin ComGC Machinery gene
  ACI6O7_RS11380 (LLWA12L8_FAMOGCFE_02281) comGB 2273885..2274958 (-) 1074 WP_010906319.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACI6O7_RS11385 (LLWA12L8_FAMOGCFE_02282) comGA 2274852..2275790 (-) 939 WP_143459428.1 competence type IV pilus ATPase ComGA Machinery gene

Sequence

Protein


Download         Length: 357 a.a.        Molecular weight: 40330.51 Da        Isoelectric Point: 10.3000

>NTDB_id=1160559 ACI6O7_RS11380 WP_010906319.1 2273885..2274958(-) (comGB) [Lactococcus lactis strain IMDO WA12L8]
MSLGHQKIGIKKLISYLQMDISHLLKPKGKKLRLIKQAKLIQLMGNLLNSGFNLGEVINFLSLSKLVEKEFTLKMKEGLA
SGQALSELLESLSFSKNVVTQLALVEVHGNLSGTMQLVELHLKKQLKVKNKLVEVATYPILLLIFLVGIMWGLKNYLLPQ
LNSGSNFATLLINHLPLVFFSFGAFIFLLTALSVTLFKRKSAIMNFTFLVKLPLVHSFIRLYLTAYFAREWGNLIAQGVE
LRQIINLMKKQKSRIFSEVGKNLDLELNAGRSFEQAVSKLALFLPELSLMIEYGAIKDKLGLELSLYADECWEQFFTKID
RLMQLIQPLVFIFVALMIILLYAAMLLPIYSNMGSGI

Nucleotide


Download         Length: 1074 bp        

>NTDB_id=1160559 ACI6O7_RS11380 WP_010906319.1 2273885..2274958(-) (comGB) [Lactococcus lactis strain IMDO WA12L8]
TTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTACTTACAAATGGATATCTCACACCTACTGAAGCC
AAAAGGGAAAAAATTAAGACTGATTAAACAAGCCAAACTTATCCAACTGATGGGAAATCTTTTGAATAGTGGATTTAATT
TAGGAGAAGTGATAAATTTCTTATCTTTATCAAAACTTGTGGAAAAAGAATTTACATTAAAAATGAAAGAAGGTCTCGCT
TCTGGTCAAGCTTTATCAGAGCTTTTAGAAAGTCTTTCATTTTCTAAAAATGTGGTGACACAACTTGCTTTGGTAGAAGT
GCATGGTAACTTGTCAGGGACGATGCAATTAGTTGAACTTCATCTAAAAAAACAGCTTAAAGTTAAAAATAAATTAGTGG
AAGTTGCTACTTATCCAATATTGTTATTAATTTTTCTGGTTGGAATTATGTGGGGCTTAAAAAATTATTTACTACCACAA
CTCAATAGTGGCAGTAACTTTGCTACTCTATTGATTAATCATTTACCCTTAGTATTTTTTTCGTTTGGAGCTTTTATATT
TTTACTGACAGCTTTGTCAGTAACTCTTTTTAAACGAAAATCAGCAATAATGAATTTTACATTTCTTGTTAAATTACCTC
TGGTTCATTCTTTTATCCGTTTATATTTAACAGCTTACTTTGCAAGAGAATGGGGAAATCTAATTGCTCAAGGTGTTGAA
TTACGTCAAATTATTAACTTGATGAAAAAACAAAAAAGTCGAATTTTTTCAGAAGTTGGCAAGAATCTTGATTTAGAATT
GAATGCTGGTCGGTCTTTTGAACAAGCTGTCAGTAAACTTGCGCTTTTTTTACCCGAGCTCTCGTTAATGATTGAATATG
GAGCTATTAAAGATAAATTAGGCTTAGAGCTTTCGCTTTATGCGGATGAATGTTGGGAACAATTTTTTACAAAGATAGAT
CGTTTAATGCAATTAATCCAACCTCTTGTTTTTATTTTCGTAGCATTGATGATTATTTTGCTATATGCAGCCATGTTACT
CCCCATCTATTCAAATATGGGTTCTGGAATATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-348)

Type II secretion system (T2SS), protein F (T2SSF)

(41-159)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A552YT77

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Lactococcus lactis subsp. cremoris KW2

83.578

95.518

0.798
  comYB Streptococcus gordonii str. Challis substr. CH1

53.959

95.518

0.515
  comYB Streptococcus mutans UA140

53.372

95.518

0.51
  comYB Streptococcus mutans UA159

53.079

95.518

0.507
  comGB/cglB Streptococcus mitis SK321

51.343

93.838

0.482
  comGB/cglB Streptococcus pneumoniae TIGR4

51.045

93.838

0.479
  comGB/cglB Streptococcus pneumoniae Rx1

51.045

93.838

0.479
  comGB/cglB Streptococcus pneumoniae D39

51.045

93.838

0.479
  comGB/cglB Streptococcus pneumoniae R6

51.045

93.838

0.479
  comGB/cglB Streptococcus mitis NCTC 12261

50.448

93.838

0.473

Multiple sequence alignment