Detailed information NTG1155554

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: QNH68_RS00185
• Genome accession: NZ_OX352944
• Coordinates: 29927..30208 (+)
• Length: 93 a.a.
• NCBI ID: WP_011921720.1
• Uniprot ID: A0A0M9FL05
• Organism: Streptococcus suis isolate 861160_LM_H
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 24927..35208

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QNH68_RS00165	-	26597..26962 (+)	366	WP_002936568.1	DUF1033 family protein	-
QNH68_RS00170	-	26997..27940 (-)	944	Protein_17	S66 peptidase family protein	-
QNH68_RS00175	comYA	28026..28976 (+)	951	WP_011921718.1	competence type IV pilus ATPase ComGA	Machinery gene
QNH68_RS00180	comYB	28888..29925 (+)	1038	WP_255304289.1	competence type IV pilus assembly protein ComGB	Machinery gene
QNH68_RS00185	comYC	29927..30208 (+)	282	WP_011921720.1	competence type IV pilus major pilin ComGC	Machinery gene
QNH68_RS00190	comGD	30189..30596 (+)	408	WP_011921721.1	competence type IV pilus minor pilin ComGD	-
QNH68_RS00195	comYE	30568..30861 (+)	294	WP_011921722.1	competence type IV pilus minor pilin ComGE	Machinery gene
QNH68_RS00200	comGF/cglF	30848..31282 (+)	435	WP_011922561.1	competence type IV pilus minor pilin ComGF	Machinery gene
QNH68_RS00205	comGG	31260..31670 (+)	411	WP_011921724.1	competence type IV pilus minor pilin ComGG	-
QNH68_RS00210	comYH	31727..32680 (+)	954	WP_024406069.1	class I SAM-dependent methyltransferase	Machinery gene
QNH68_RS00215	-	32730..33917 (+)	1188	WP_012775473.1	acetate kinase	-
QNH68_RS00220	-	34231..34782 (+)	552	WP_012775474.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10408.34 Da
• Isoelectric Point: 7.0117

>NTDB_id=1155554 QNH68_RS00185 WP_011921720.1 29927..30208(+) (comYC) [Streptococcus suis isolate 861160_LM_H]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEHDEEATVADLQAKGYI
TEKQAKQYATAKK

Nucleotide

• Length: 282 bp

>NTDB_id=1155554 QNH68_RS00185 WP_011921720.1 29927..30208(+) (comYC) [Streptococcus suis isolate 861160_LM_H]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTGGTCGTTTTAGGGATCATTAGCCTGCT
CTTGCTCCTCTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGTCAGATGGAGCTCTATGAATTGGAACATGACGAGGAAGCAACGGTGGCAGATTTGCAGGCGAAAGGTTATATT
ACTGAAAAACAAGCAAAACAGTATGCTACGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0M9FL05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	100	100	1
comGC/cglC	Streptococcus mitis SK321	68.235	91.398	0.624
comGC/cglC	Streptococcus mitis NCTC 12261	68.235	91.398	0.624
comGC/cglC	Streptococcus pneumoniae D39	70.37	87.097	0.613
comGC/cglC	Streptococcus pneumoniae R6	70.37	87.097	0.613
comGC/cglC	Streptococcus pneumoniae TIGR4	70.37	87.097	0.613
comGC/cglC	Streptococcus pneumoniae Rx1	70.37	87.097	0.613
comYC	Streptococcus gordonii str. Challis substr. CH1	61.798	95.699	0.591
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	56.818	94.624	0.538
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Bacillus subtilis subsp. subtilis str. 168	49.333	80.645	0.398
comGC	Latilactobacillus sakei subsp. sakei 23K	43.75	86.022	0.376