Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   CKV85_RS10465 Genome accession   NZ_LT906454
Coordinates   2125172..2126125 (-) Length   317 a.a.
NCBI ID   WP_017770215.1    Uniprot ID   -
Organism   Streptococcus acidominimus strain NCTC11291     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2120172..2131125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV85_RS10425 (SAMEA4504048_02227) - 2120200..2121390 (-) 1191 WP_017770223.1 acetate kinase -
  CKV85_RS10430 (SAMEA4504048_02228) comYH 2121451..2122404 (-) 954 WP_095123575.1 class I SAM-dependent methyltransferase Machinery gene
  CKV85_RS10435 (SAMEA4504048_02229) comGG 2122476..2122865 (-) 390 WP_197697097.1 competence type IV pilus minor pilin ComGG -
  CKV85_RS10440 (SAMEA4504048_02230) comYF 2122843..2123280 (-) 438 WP_017770220.1 competence type IV pilus minor pilin ComGF Machinery gene
  CKV85_RS10445 comGE 2123258..2123503 (-) 246 WP_231909805.1 competence system putative prepilin ComGE -
  CKV85_RS10450 (SAMEA4504048_02231) comGD 2123529..2123945 (-) 417 WP_095123577.1 competence type IV pilus minor pilin ComGD -
  CKV85_RS10455 (SAMEA4504048_02232) comYC 2123929..2124219 (-) 291 WP_095123578.1 competence type IV pilus major pilin ComGC Machinery gene
  CKV85_RS10460 (SAMEA4504048_02233) comYB 2124220..2125170 (-) 951 WP_269457190.1 competence type IV pilus assembly protein ComGB Machinery gene
  CKV85_RS10465 (SAMEA4504048_02234) comYA 2125172..2126125 (-) 954 WP_017770215.1 competence type IV pilus ATPase ComGA Machinery gene
  CKV85_RS10470 (SAMEA4504048_02235) - 2126245..2126625 (-) 381 WP_017770214.1 DUF1033 family protein -
  CKV85_RS10475 (SAMEA4504048_02236) rpoC 2126942..2130574 (-) 3633 WP_095123579.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35934.90 Da        Isoelectric Point: 6.2409

>NTDB_id=1147514 CKV85_RS10465 WP_017770215.1 2125172..2126125(-) (comYA) [Streptococcus acidominimus strain NCTC11291]
MVQDLARLLIHEAKKENAQDIYIIPRTEDYDVFMRIGDDRRFIETYGFDRMVNLISHFKFVAGMTVGEKRRSQLGSCDYE
LDDGQIVSLRLSTVGDYRGRESLVIRLLHDGRQDLHYWFDGMRDIMDAVRSRGLYLFSGPTGSGKTTLMYQLLKEKFSGQ
QIISIEDPVEIKDEAILQLQLNESIDMTYDSLIKLSLRHRPDVLVIGEIRDRETARAAIRASLTGATVFSTIHAKSISGV
YSRLLELGVSQDELAHSLSGICYQRLIGGGGLIDVATKDFQDHKPGKWNQALEDLFKAGHLSREQVQTERIVYSQAG

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1147514 CKV85_RS10465 WP_017770215.1 2125172..2126125(-) (comYA) [Streptococcus acidominimus strain NCTC11291]
ATGGTACAAGATTTAGCACGCTTATTAATACATGAAGCAAAAAAGGAAAATGCTCAGGATATTTATATCATTCCTCGTAC
GGAGGATTATGATGTTTTTATGCGTATCGGCGATGATAGGAGATTTATTGAGACATATGGCTTTGATCGGATGGTTAATC
TTATTAGTCACTTTAAATTTGTGGCAGGAATGACAGTTGGTGAGAAACGGCGTAGTCAGTTAGGATCCTGTGATTATGAA
CTAGATGATGGTCAGATTGTCTCTTTACGCTTATCAACGGTTGGTGATTATCGTGGGCGCGAAAGTCTTGTTATCCGTCT
CTTGCATGATGGGCGCCAAGATCTCCATTATTGGTTTGATGGCATGCGGGACATTATGGATGCGGTCCGTTCAAGGGGGC
TATATCTTTTTTCGGGGCCAACTGGGAGTGGTAAGACGACTCTCATGTACCAATTGTTAAAAGAAAAGTTTTCTGGCCAG
CAGATCATTTCCATTGAAGATCCTGTTGAGATTAAGGATGAAGCGATTTTACAGCTGCAGTTAAATGAAAGCATTGACAT
GACTTATGACAGCTTAATCAAGCTTTCCTTGAGACATCGTCCGGATGTTTTGGTTATTGGGGAAATTCGGGATCGCGAAA
CTGCTAGGGCGGCCATTCGTGCCAGTCTGACAGGCGCTACTGTTTTCTCGACTATTCATGCCAAAAGCATATCAGGTGTT
TATAGCCGTCTTTTAGAACTAGGAGTATCCCAAGATGAGTTAGCGCATAGCTTATCGGGAATTTGTTACCAGCGTTTAAT
CGGAGGAGGTGGATTGATCGATGTGGCAACCAAAGATTTCCAAGACCACAAGCCCGGAAAATGGAATCAAGCCTTGGAAG
ACCTTTTTAAAGCGGGACATCTTAGCAGGGAGCAGGTCCAGACAGAGAGGATTGTCTATTCACAAGCAGGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

67.203

98.107

0.659
  comYA Streptococcus mutans UA159

67.203

98.107

0.659
  comYA Streptococcus gordonii str. Challis substr. CH1

65.506

99.685

0.653
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.65

99.054

0.64
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.331

99.054

0.637
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.331

99.054

0.637
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.331

99.054

0.637
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.331

99.054

0.637
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

97.792

0.612
  comGA Lactococcus lactis subsp. cremoris KW2

52.215

99.685

0.521

Multiple sequence alignment