Detailed information NTG1141938

Bioinformatically predicted

Overview

• Name: comGA/cglA/cilD
• Type: Machinery gene
• Locus tag: DQK98_RS10155
• Genome accession: NZ_LS483449
• Coordinates: 1897681..1898622 (-)
• Length: 313 a.a.
• NCBI ID: WP_000249550.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 4041STDY6836170
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1892681..1903622

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQK98_RS10115	comYH	1893174..1894127 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
DQK98_RS10120	-	1894188..1894775 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
DQK98_RS10125	comGG/cglG	1894912..1895325 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
DQK98_RS10130	comGF/cglF	1895303..1895764 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQK98_RS10135	comGE/cglE	1895727..1896029 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQK98_RS10140	comGD/cglD	1895992..1896396 (-)	405	WP_000588006.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQK98_RS10145	comGC/cglC	1896389..1896715 (-)	327	WP_000738638.1	comG operon protein ComGC	Machinery gene
DQK98_RS10150	comGB/cglB	1896717..1897733 (-)	1017	WP_075270915.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQK98_RS10155	comGA/cglA/cilD	1897681..1898622 (-)	942	WP_000249550.1	competence type IV pilus ATPase ComGA	Machinery gene
DQK98_RS10160	-	1898698..1899063 (-)	366	WP_000286415.1	DUF1033 family protein	-
DQK98_RS10165	-	1899214..1900272 (-)	1059	WP_000649466.1	zinc-dependent alcohol dehydrogenase family protein	-
DQK98_RS10170	nagA	1900435..1901586 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-
DQK98_RS10175	-	1901739..1903556 (-)	1818	WP_001220847.1	acyltransferase family protein	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 35516.43 Da
• Isoelectric Point: 6.0083

>NTDB_id=1141938 DQK98_RS10155 WP_000249550.1 1897681..1898622(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 4041STDY6836170]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide

• Length: 942 bp

>NTDB_id=1141938 DQK98_RS10155 WP_000249550.1 1897681..1898622(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 4041STDY6836170]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCTAAGTT
AGATGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (9-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	99.361	100	0.994
comGA/cglA/cilD	Streptococcus pneumoniae D39	99.361	100	0.994
comGA/cglA/cilD	Streptococcus pneumoniae R6	99.361	100	0.994
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	99.361	100	0.994
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	96.486	100	0.965
comYA	Streptococcus gordonii str. Challis substr. CH1	78.387	99.042	0.776
comYA	Streptococcus mutans UA159	66.238	99.361	0.658
comYA	Streptococcus mutans UA140	66.238	99.361	0.658
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	62.903	99.042	0.623
comGA	Lactococcus lactis subsp. cremoris KW2	55.128	99.681	0.55
comGA	Latilactobacillus sakei subsp. sakei 23K	41.912	86.901	0.364