Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DQK98_RS10135 Genome accession   NZ_LS483449
Coordinates   1895727..1896029 (-) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836170     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1890727..1901029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK98_RS10105 rnpA 1891413..1891784 (-) 372 WP_000739246.1 ribonuclease P protein component -
  DQK98_RS12175 - 1891801..1891932 (-) 132 WP_000768904.1 hypothetical protein -
  DQK98_RS10110 - 1891933..1893123 (-) 1191 WP_000167766.1 acetate kinase -
  DQK98_RS10115 comYH 1893174..1894127 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  DQK98_RS10120 - 1894188..1894775 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  DQK98_RS10125 comGG/cglG 1894912..1895325 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQK98_RS10130 comGF/cglF 1895303..1895764 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQK98_RS10135 comGE/cglE 1895727..1896029 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQK98_RS10140 comGD/cglD 1895992..1896396 (-) 405 WP_000588006.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQK98_RS10145 comGC/cglC 1896389..1896715 (-) 327 WP_000738638.1 comG operon protein ComGC Machinery gene
  DQK98_RS10150 comGB/cglB 1896717..1897733 (-) 1017 WP_075270915.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQK98_RS10155 comGA/cglA/cilD 1897681..1898622 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  DQK98_RS10160 - 1898698..1899063 (-) 366 WP_000286415.1 DUF1033 family protein -
  DQK98_RS10165 - 1899214..1900272 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=1141934 DQK98_RS10135 WP_000413380.1 1895727..1896029(-) (comGE/cglE) [Streptococcus pneumoniae strain 4041STDY6836170]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=1141934 DQK98_RS10135 WP_000413380.1 1895727..1896029(-) (comGE/cglE) [Streptococcus pneumoniae strain 4041STDY6836170]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment