Detailed information NTG1141853

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: DQK99_RS10395
• Genome accession: NZ_LS483448
• Coordinates: 1885868..1886347 (-)
• Length: 159 a.a.
• NCBI ID: WP_000588911.1
• Uniprot ID: A0A2I5MSB2
• Organism: Streptococcus pneumoniae strain 4041STDY6836167
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1880868..1891347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQK99_RS10375	comX/comX2	1883043..1883522 (-)	480	WP_000588911.1	sigma-70 family RNA polymerase sigma factor	Regulator
DQK99_RS10395	comX/comX2	1885868..1886347 (-)	480	WP_000588911.1	sigma-70 family RNA polymerase sigma factor	Regulator
DQK99_RS10400	nusG	1886469..1887005 (-)	537	WP_000376736.1	transcription termination/antitermination protein NusG	-
DQK99_RS10405	secE	1887060..1887236 (-)	177	WP_001210991.1	preprotein translocase subunit SecE	-
DQK99_RS10410	rpmG	1887246..1887398 (-)	153	WP_001809950.1	50S ribosomal protein L33	-
DQK99_RS10415	pbp2a	1887451..1889646 (-)	2196	WP_000762628.1	penicillin-binding protein PBP2A	-
DQK99_RS10420	-	1889733..1890608 (+)	876	WP_001160819.1	RluA family pseudouridine synthase	-

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 19873.52 Da
• Isoelectric Point: 7.3797

>NTDB_id=1141853 DQK99_RS10395 WP_000588911.1 1885868..1886347(-) (comX/comX2) [Streptococcus pneumoniae strain 4041STDY6836167]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGELSHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide

• Length: 480 bp

>NTDB_id=1141853 DQK99_RS10395 WP_000588911.1 1885868..1886347(-) (comX/comX2) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGTTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGCTCAGTCATCGTATAAGTGAGGGAGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A2I5MSB2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX2	Streptococcus pneumoniae Rx1	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae Rx1	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae D39	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae D39	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae R6	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae R6	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae TIGR4	98.742	100	0.987
comX/comX1	Streptococcus pneumoniae TIGR4	98.742	100	0.987
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	91.824	100	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	91.824	100	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	89.937	100	0.899
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	88.608	99.371	0.881
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	48.077	98.113	0.472
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	48.077	98.113	0.472
comX/sigX	Streptococcus suis D9	46.358	94.969	0.44
comX/sigX	Streptococcus suis isolate S10	46.358	94.969	0.44
comX/sigX	Streptococcus suis P1/7	46.358	94.969	0.44
comX/sigX	Streptococcus mutans UA159	45.333	94.34	0.428
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	39.216	96.226	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40	94.34	0.377
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40	94.34	0.377
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40	94.34	0.377