Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   DQN54_RS10150 Genome accession   NZ_LS483417
Coordinates   1879000..1879326 (-) Length   108 a.a.
NCBI ID   WP_000738625.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NCTC11902     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1874000..1884326
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN54_RS10110 (NCTC11902_01939) rnpA 1874018..1874389 (-) 372 WP_000739246.1 ribonuclease P protein component -
  DQN54_RS12050 - 1874406..1874537 (-) 132 WP_000768904.1 hypothetical protein -
  DQN54_RS10115 (NCTC11902_01940) - 1874538..1875728 (-) 1191 WP_000167769.1 acetate kinase -
  DQN54_RS10120 (NCTC11902_01941) comYH 1875779..1876732 (-) 954 WP_000345127.1 class I SAM-dependent methyltransferase Machinery gene
  DQN54_RS10125 - 1876793..1877387 (-) 595 Protein_1884 class I SAM-dependent methyltransferase -
  DQN54_RS10130 (NCTC11902_01944) comGG/cglG 1877490..1877936 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQN54_RS10135 (NCTC11902_01945) comGF/cglF 1877914..1878375 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQN54_RS10140 (NCTC11902_01946) comGE/cglE 1878338..1878640 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQN54_RS10145 (NCTC11902_01947) comGD/cglD 1878603..1879007 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQN54_RS10150 (NCTC11902_01948) comGC/cglC 1879000..1879326 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  DQN54_RS10155 (NCTC11902_01949) comGB/cglB 1879328..1880344 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQN54_RS10160 (NCTC11902_01950) comGA/cglA/cilD 1880292..1881233 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  DQN54_RS10165 (NCTC11902_01951) - 1881308..1881673 (-) 366 WP_000286415.1 DUF1033 family protein -
  DQN54_RS10170 (NCTC11902_01952) - 1881824..1882882 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -
  DQN54_RS10175 (NCTC11902_01953) nagA 1883045..1884196 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12143.28 Da        Isoelectric Point: 10.0055

>NTDB_id=1140908 DQN54_RS10150 WP_000738625.1 1879000..1879326(-) (comGC/cglC) [Streptococcus pneumoniae strain NCTC11902]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1140908 DQN54_RS10150 WP_000738625.1 1879000..1879326(-) (comGC/cglC) [Streptococcus pneumoniae strain NCTC11902]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTAGTAGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGATAAAAATGAAGATGCTACTCTGAGCAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae Rx1

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae D39

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae R6

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae TIGR4

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

92.857

90.741

0.843
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comYC Streptococcus suis isolate S10

64.773

81.481

0.528
  comGC Staphylococcus aureus MW2

47.674

79.63

0.38
  comGC Staphylococcus aureus N315

47.674

79.63

0.38

Multiple sequence alignment