Detailed information NTG1140906

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: DQN54_RS10140
• Genome accession: NZ_LS483417
• Coordinates: 1878338..1878640 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NCTC11902
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1873338..1883640

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN54_RS10110 (NCTC11902_01939)	rnpA	1874018..1874389 (-)	372	WP_000739246.1	ribonuclease P protein component	-
DQN54_RS12050	-	1874406..1874537 (-)	132	WP_000768904.1	hypothetical protein	-
DQN54_RS10115 (NCTC11902_01940)	-	1874538..1875728 (-)	1191	WP_000167769.1	acetate kinase	-
DQN54_RS10120 (NCTC11902_01941)	comYH	1875779..1876732 (-)	954	WP_000345127.1	class I SAM-dependent methyltransferase	Machinery gene
DQN54_RS10125	-	1876793..1877387 (-)	595	Protein_1884	class I SAM-dependent methyltransferase	-
DQN54_RS10130 (NCTC11902_01944)	comGG/cglG	1877490..1877936 (-)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
DQN54_RS10135 (NCTC11902_01945)	comGF/cglF	1877914..1878375 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQN54_RS10140 (NCTC11902_01946)	comGE/cglE	1878338..1878640 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQN54_RS10145 (NCTC11902_01947)	comGD/cglD	1878603..1879007 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQN54_RS10150 (NCTC11902_01948)	comGC/cglC	1879000..1879326 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
DQN54_RS10155 (NCTC11902_01949)	comGB/cglB	1879328..1880344 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQN54_RS10160 (NCTC11902_01950)	comGA/cglA/cilD	1880292..1881233 (-)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
DQN54_RS10165 (NCTC11902_01951)	-	1881308..1881673 (-)	366	WP_000286415.1	DUF1033 family protein	-
DQN54_RS10170 (NCTC11902_01952)	-	1881824..1882882 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=1140906 DQN54_RS10140 WP_000413382.1 1878338..1878640(-) (comGE/cglE) [Streptococcus pneumoniae strain NCTC11902]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=1140906 DQN54_RS10140 WP_000413382.1 1878338..1878640(-) (comGE/cglE) [Streptococcus pneumoniae strain NCTC11902]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4