Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   T303_RS00255 Genome accession   NZ_CP006819
Coordinates   38394..38720 (-) Length   108 a.a.
NCBI ID   WP_002946126.1    Uniprot ID   A0A0E2Q1B3
Organism   Streptococcus thermophilus ASCC 1275     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 33394..43720
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  T303_RS11280 (T303_00210) - 33659..33997 (-) 339 WP_224103197.1 CPBP family intramembrane glutamic endopeptidase -
  T303_RS11285 - 34041..34316 (-) 276 WP_011681681.1 hypothetical protein -
  T303_RS00220 (T303_00215) - 34328..34526 (-) 199 Protein_41 helix-turn-helix transcriptional regulator -
  T303_RS00225 (T303_00220) - 34775..35968 (-) 1194 WP_014608740.1 acetate kinase -
  T303_RS00230 (T303_00225) comYH 36024..36980 (-) 957 WP_011681684.1 class I SAM-dependent methyltransferase Machinery gene
  T303_RS00235 (T303_00230) comGG 37025..37342 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG -
  T303_RS00240 (T303_00235) comYF 37320..37757 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  T303_RS00245 (T303_00240) comGE 37741..38034 (-) 294 WP_024704238.1 competence type IV pilus minor pilin ComGE -
  T303_RS00250 (T303_00245) comYD 38006..38434 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  T303_RS00255 (T303_00250) comYC 38394..38720 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  T303_RS00260 (T303_00255) comYB 38717..39817 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  T303_RS00265 (T303_00260) comGA/cglA/cilD 39699..40640 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  T303_RS00270 (T303_00265) - 40721..41083 (-) 363 WP_014622006.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 11914.00 Da        Isoelectric Point: 9.9219

>NTDB_id=114064 T303_RS00255 WP_002946126.1 38394..38720(-) (comYC) [Streptococcus thermophilus ASCC 1275]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=114064 T303_RS00255 WP_002946126.1 38394..38720(-) (comYC) [Streptococcus thermophilus ASCC 1275]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q1B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus mutans UA140

69.231

96.296

0.667
  comYC Streptococcus mutans UA159

69.231

96.296

0.667
  comYC Streptococcus gordonii str. Challis substr. CH1

63.81

97.222

0.62
  comGC/cglC Streptococcus mitis SK321

62.264

98.148

0.611
  comGC/cglC Streptococcus mitis NCTC 12261

58.333

100

0.583
  comGC/cglC Streptococcus pneumoniae D39

58.491

98.148

0.574
  comGC/cglC Streptococcus pneumoniae R6

58.491

98.148

0.574
  comGC/cglC Streptococcus pneumoniae Rx1

58.491

98.148

0.574
  comGC/cglC Streptococcus pneumoniae TIGR4

58.491

98.148

0.574
  comGC Lactococcus lactis subsp. cremoris KW2

56.604

98.148

0.556
  comYC Streptococcus suis isolate S10

60.227

81.481

0.491
  comGC Staphylococcus aureus MW2

50

72.222

0.361
  comGC Staphylococcus aureus N315

50

72.222

0.361

Multiple sequence alignment