Detailed information NTG1140324

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: DQN23_RS00715
• Genome accession: NZ_LS483403
• Coordinates: 107072..107365 (+)
• Length: 97 a.a.
• NCBI ID: WP_020915989.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain NCTC13774
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 102072..112365

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN23_RS00700 (NCTC13774_00141)	-	104724..105092 (+)	369	WP_020915986.1	DUF1033 family protein	-
DQN23_RS00705 (NCTC13774_00142)	comYA	105164..106105 (+)	942	WP_020915987.1	competence type IV pilus ATPase ComGA	Machinery gene
DQN23_RS00710 (NCTC13774_00143)	comYB	106029..107072 (+)	1044	WP_020915988.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQN23_RS00715 (NCTC13774_00144)	comYC	107072..107365 (+)	294	WP_020915989.1	competence type IV pilus major pilin ComGC	Machinery gene
DQN23_RS00720 (NCTC13774_00145)	comYD	107349..107780 (+)	432	WP_020915990.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQN23_RS00725 (NCTC13774_00146)	comYE	107734..108027 (+)	294	WP_020915991.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQN23_RS00730 (NCTC13774_00147)	comYF	108011..108448 (+)	438	WP_043894883.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQN23_RS00735 (NCTC13774_00148)	comGG	108420..108770 (+)	351	WP_020915993.1	competence type IV pilus minor pilin ComGG	-
DQN23_RS00740 (NCTC13774_00149)	comYH	108824..109780 (+)	957	WP_020915994.1	class I SAM-dependent methyltransferase	Machinery gene
DQN23_RS00745 (NCTC13774_00150)	-	109834..111033 (+)	1200	WP_020915995.1	acetate kinase	-
DQN23_RS00750 (NCTC13774_00151)	-	111193..111390 (+)	198	WP_020915996.1	helix-turn-helix transcriptional regulator	-
DQN23_RS00755 (NCTC13774_00152)	-	111407..111607 (+)	201	WP_058814360.1	hypothetical protein	-
DQN23_RS00760 (NCTC13774_00153)	-	111608..112063 (+)	456	WP_231853254.1	ABC transporter permease	-

Sequence

Protein

• Length: 97 a.a.
• Molecular weight: 11018.16 Da
• Isoelectric Point: 10.1006

>NTDB_id=1140324 DQN23_RS00715 WP_020915989.1 107072..107365(+) (comYC) [Streptococcus lutetiensis strain NCTC13774]
MKNIWKKLRKKSVEAFTLVEMLIVLLIIGVLMLLFVPNLSKQKEVVHEKGDAAVVKVVESQMELYEVKTGKQPTVNDLVK
AEYISKDQAQTYNAAKK

Nucleotide

• Length: 294 bp

>NTDB_id=1140324 DQN23_RS00715 WP_020915989.1 107072..107365(+) (comYC) [Streptococcus lutetiensis strain NCTC13774]
ATGAAAAACATTTGGAAAAAACTACGTAAAAAGTCTGTAGAAGCTTTTACACTTGTGGAGATGTTGATTGTTTTGCTAAT
CATTGGTGTCTTGATGCTGTTATTTGTGCCAAACTTGAGCAAGCAAAAAGAGGTTGTGCATGAAAAAGGAGATGCTGCTG
TTGTCAAAGTTGTCGAAAGTCAGATGGAGCTTTATGAAGTGAAGACAGGTAAACAACCAACTGTAAATGATTTGGTGAAA
GCTGAATATATTTCAAAAGACCAAGCTCAAACATATAATGCGGCTAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (13-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	68.539	91.753	0.629
comYC	Streptococcus suis isolate S10	60.87	94.845	0.577
comGC/cglC	Streptococcus mitis SK321	56.989	95.876	0.546
comGC/cglC	Streptococcus pneumoniae Rx1	56.522	94.845	0.536
comGC/cglC	Streptococcus pneumoniae D39	56.522	94.845	0.536
comGC/cglC	Streptococcus pneumoniae R6	56.522	94.845	0.536
comGC/cglC	Streptococcus pneumoniae TIGR4	56.522	94.845	0.536
comGC/cglC	Streptococcus mitis NCTC 12261	56.522	94.845	0.536
comYC	Streptococcus mutans UA140	56.322	89.691	0.505
comYC	Streptococcus mutans UA159	56.322	89.691	0.505
comGC	Lactococcus lactis subsp. cremoris KW2	51.685	91.753	0.474
comGC	Latilactobacillus sakei subsp. sakei 23K	45.57	81.443	0.371