Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQN23_RS00710 Genome accession   NZ_LS483403
Coordinates   106029..107072 (+) Length   347 a.a.
NCBI ID   WP_020915988.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC13774     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 101029..112072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN23_RS00700 (NCTC13774_00141) - 104724..105092 (+) 369 WP_020915986.1 DUF1033 family protein -
  DQN23_RS00705 (NCTC13774_00142) comYA 105164..106105 (+) 942 WP_020915987.1 competence type IV pilus ATPase ComGA Machinery gene
  DQN23_RS00710 (NCTC13774_00143) comYB 106029..107072 (+) 1044 WP_020915988.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQN23_RS00715 (NCTC13774_00144) comYC 107072..107365 (+) 294 WP_020915989.1 competence type IV pilus major pilin ComGC Machinery gene
  DQN23_RS00720 (NCTC13774_00145) comYD 107349..107780 (+) 432 WP_020915990.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQN23_RS00725 (NCTC13774_00146) comYE 107734..108027 (+) 294 WP_020915991.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQN23_RS00730 (NCTC13774_00147) comYF 108011..108448 (+) 438 WP_043894883.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQN23_RS00735 (NCTC13774_00148) comGG 108420..108770 (+) 351 WP_020915993.1 competence type IV pilus minor pilin ComGG -
  DQN23_RS00740 (NCTC13774_00149) comYH 108824..109780 (+) 957 WP_020915994.1 class I SAM-dependent methyltransferase Machinery gene
  DQN23_RS00745 (NCTC13774_00150) - 109834..111033 (+) 1200 WP_020915995.1 acetate kinase -
  DQN23_RS00750 (NCTC13774_00151) - 111193..111390 (+) 198 WP_020915996.1 helix-turn-helix transcriptional regulator -
  DQN23_RS00755 (NCTC13774_00152) - 111407..111607 (+) 201 WP_058814360.1 hypothetical protein -
  DQN23_RS00760 (NCTC13774_00153) - 111608..112063 (+) 456 WP_231853254.1 ABC transporter permease -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39552.77 Da        Isoelectric Point: 9.2096

>NTDB_id=1140323 DQN23_RS00710 WP_020915988.1 106029..107072(+) (comYB) [Streptococcus lutetiensis strain NCTC13774]
MSKLKALLGTDILALRKQKSKKLPFKKQQKVIQLFNNLFNSGFNLTEIVSFLRRSQLLAEVYVDSMQESLLSGASLADMM
AKLGFSDTIVTQIALADVHGNCQQSLLKIDGYLASMSVVRKKLIEVATYPLILFSFLILIMLGLKNYLLPQLENQNFATQ
IISHFPMIFLGGFALLALGILLGVLYAEHLSPIYLYSQLSRLPIFGRHVRLYLTAYYAREWGNLIGQGIELMEIVELMQR
QKSRLFQEIGKDMQEALLSGQSFHQKVLDYPFFLRELSLMIEYGEVKSKLGRELDIYAEETWQNFFSQLTQATQLIQPLV
FVFVASIIVLIYVAMLLPMYQNMGGNF

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1140323 DQN23_RS00710 WP_020915988.1 106029..107072(+) (comYB) [Streptococcus lutetiensis strain NCTC13774]
ATGAGCAAATTAAAAGCCTTGCTAGGGACGGACATATTGGCCTTGAGGAAGCAAAAATCGAAAAAATTGCCCTTTAAAAA
ACAGCAGAAGGTGATTCAATTATTTAACAATCTCTTTAACAGCGGCTTTAATTTAACAGAAATTGTTTCTTTTTTGAGAC
GAAGTCAGTTGTTGGCGGAAGTTTATGTGGACAGTATGCAAGAGTCATTGTTAAGTGGGGCAAGTTTGGCAGATATGATG
GCTAAGCTGGGCTTTTCAGATACAATTGTCACCCAGATTGCTCTTGCGGATGTTCATGGGAATTGTCAGCAGAGTTTGTT
AAAAATTGATGGTTACTTGGCTAGTATGTCAGTTGTTCGAAAGAAATTGATTGAAGTGGCGACTTATCCTTTGATTTTGT
TTAGCTTTTTAATTCTGATTATGTTGGGCTTGAAAAATTATTTGCTGCCGCAGTTGGAAAATCAAAATTTTGCAACTCAG
ATTATCAGCCATTTTCCTATGATTTTTTTGGGTGGCTTTGCTCTTTTAGCTTTAGGAATTCTGCTTGGGGTTCTGTATGC
CGAGCACTTATCGCCAATTTATCTGTATAGTCAGTTAAGTCGTTTGCCAATATTTGGTCGGCACGTGCGCCTTTATTTGA
CGGCTTATTATGCGCGTGAGTGGGGAAATCTTATCGGACAAGGTATCGAACTGATGGAGATTGTAGAGCTTATGCAGCGG
CAAAAATCACGTCTCTTTCAGGAAATTGGAAAAGATATGCAGGAAGCTTTGTTGTCTGGTCAGTCTTTTCATCAGAAAGT
GCTGGATTACCCTTTCTTTTTGCGTGAACTTAGCTTAATGATTGAATATGGCGAGGTCAAGTCAAAATTAGGTCGTGAGT
TAGATATTTATGCCGAAGAGACTTGGCAGAATTTCTTTAGTCAATTGACGCAGGCAACGCAGCTAATTCAGCCTTTGGTC
TTTGTCTTTGTTGCTTCAATCATCGTTTTAATTTATGTGGCAATGCTTTTGCCGATGTATCAAAATATGGGAGGAAATTT
TTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

64.873

91.066

0.591
  comYB Streptococcus mutans UA159

64.873

91.066

0.591
  comYB Streptococcus gordonii str. Challis substr. CH1

57.941

97.983

0.568
  comGB/cglB Streptococcus mitis NCTC 12261

57.27

97.118

0.556
  comGB/cglB Streptococcus mitis SK321

56.38

97.118

0.548
  comGB/cglB Streptococcus pneumoniae Rx1

55.786

97.118

0.542
  comGB/cglB Streptococcus pneumoniae D39

55.786

97.118

0.542
  comGB/cglB Streptococcus pneumoniae R6

55.786

97.118

0.542
  comGB/cglB Streptococcus pneumoniae TIGR4

55.786

97.118

0.542
  comGB Lactococcus lactis subsp. cremoris KW2

51.19

96.83

0.496

Multiple sequence alignment