Detailed information NTG1138876

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: DQM56_RS00715
• Genome accession: NZ_LS483368
• Coordinates: 124819..125142 (+)
• Length: 107 a.a.
• NCBI ID: WP_012514782.1
• Uniprot ID: B4U056
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC6176
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 119819..130142

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM56_RS00695 (NCTC6176_00139)	-	120085..122088 (+)	2004	WP_111710105.1	DUF1430 domain-containing protein	-
DQM56_RS00700 (NCTC6176_00140)	-	122090..122758 (+)	669	WP_043024949.1	ATP-binding cassette domain-containing protein	-
DQM56_RS00705 (NCTC6176_00141)	comGA/cglA	122914..123852 (+)	939	WP_111710107.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM56_RS00710 (NCTC6176_00142)	comGB	123785..124818 (+)	1034	Protein_105	competence type IV pilus assembly protein ComGB	-
DQM56_RS00715 (NCTC6176_00143)	comGC/cglC	124819..125142 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM56_RS00720 (NCTC6176_00144)	comGD	125120..125545 (+)	426	WP_012514783.1	competence type IV pilus minor pilin ComGD	-
DQM56_RS00725 (NCTC6176_00145)	comGE	125550..125792 (+)	243	WP_207622334.1	competence type IV pilus minor pilin ComGE	-
DQM56_RS00730 (NCTC6176_00146)	comYF	125779..126213 (+)	435	WP_014622144.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM56_RS00735 (NCTC6176_00147)	comGG	126191..126553 (+)	363	WP_012677238.1	competence type IV pilus minor pilin ComGG	-
DQM56_RS00740 (NCTC6176_00148)	comYH	126615..127568 (+)	954	WP_012514788.1	class I SAM-dependent methyltransferase	Machinery gene
DQM56_RS00745 (NCTC6176_00149)	-	127628..128827 (+)	1200	WP_111677653.1	acetate kinase	-
DQM56_RS00750 (NCTC6176_00150)	-	129199..129813 (-)	615	WP_021320266.1	hypothetical protein	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 12149.19 Da
• Isoelectric Point: 8.4057

>NTDB_id=1138876 DQM56_RS00715 WP_012514782.1 124819..125142(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE
DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide

• Length: 324 bp

>NTDB_id=1138876 DQM56_RS00715 WP_012514782.1 124819..125142(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTGTTAAT
CATTAGTGTTTTGATGCTGTTATTTGTTCCAAATTTAAGTAAACAAAAGGATAAGGTGACAGACACAGGCAATGCTGCGG
TGGTAAAGCTGGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG
GATGGAAGTATCAGTGACAAGCAGCAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: B4U056

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis SK321	59.813	100	0.598
comGC/cglC	Streptococcus pneumoniae Rx1	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae D39	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae R6	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae TIGR4	57.944	100	0.579
comYC	Streptococcus gordonii str. Challis substr. CH1	62.245	91.589	0.57
comGC/cglC	Streptococcus mitis NCTC 12261	61.616	92.523	0.57
comYC	Streptococcus mutans UA140	58.763	90.654	0.533
comYC	Streptococcus mutans UA159	58.763	90.654	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	56.842	88.785	0.505
comYC	Streptococcus suis isolate S10	60	74.766	0.449
comGC	Staphylococcus aureus MW2	50	72.897	0.364
comGC	Staphylococcus aureus N315	50	72.897	0.364